28526-44-5|Siphonaxanthin|(3E,5E,7E,9E,11E,13E,15E,17E)-3-(hydroxymethyl)-1-(4-hydroxy-2,6,6-trimethylcyclohexen-1-yl)-18-(4-hydroxy-2,6,6-trimethylcyclohex-2-en-1-yl)-7,12,16-trimethyloctadeca-3,5,7,9,11,13,15,17-octaen-2-one|-范德生物科技公司

Siphonaxanthin

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names：
(3E,5E,7E,9E,11E,13E,15E,17E)-3-(hydroxymethyl)-1-(4-hydroxy-2,6,6-trimethylcyclohexen-1-yl)-18-(4-hydroxy-2,6,6-trimethylcyclohex-2-en-1-yl)-7,12,16-trimethyloctadeca-3,5,7,9,11,13,15,17-octaen-2-one
CAS号：
28526-44-5
MDL Number：
MF(分子式)： C40H56O4 MW(分子量)： 600.884
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	(3E,5E,7E,9E,11E,13E,15E,17E)-3-(hydroxymethyl)-1-(4-hydroxy-2,6,6-trimethylcyclohexen-1-yl)-18-(4-hydroxy-2,6,6-trimethylcyclohex-2-en-1-yl)-7,12,16-trimethyloctadeca-3,5,7,9,11,13,15,17-octaen-2-one
英文别名	Siphonaxanthin
CAS号	28526-44-5
Inchi	InChI=1S/C40H56O4/c1-28(16-12-17-30(3)20-21-36-31(4)22-34(42)25-39(36,6)7)14-10-11-15-29(2)18-13-19-33(27-41)38(44)24-37-32(5)23-35(43)26-40(37,8)9/h10-22,34-36,41-43H,23-27H2,1-9H3/b11-10+,16-12+,18-13+,21-20+,28-14+,29-15+,30-17+,33-19+
InchiKey	SUCKEYMKNGZJHK-LANKSYMZSA-N
分子式 Formula	C40H56O4
分子量 Molecular Weight	600.884
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Siphonaxanthin(CAS:28526-44-5):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Siphonaxanthin is a marine carotenoid from green algae that induces apoptosis in human leukemia (HL-60) cells.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Sugawara T, Ganesan P, Li Z, Manabe Y, Hirata T. Siphonaxanthin, a green algal carotenoid, as a novel functional compound. Mar Drugs. 2014 Jun 19;12(6):3660-8. doi: 10.3390/md12063660. Review. PubMed PMID: 24950294; PubMed Central PMCID: PMC4071595.

[2]Zheng J, Li Z, Manabe Y, Kim M, Goto T, Kawada T, Sugawara T. Siphonaxanthin, a Carotenoid From Green Algae, Inhibits Lipogenesis in Hepatocytes via the Suppression of Liver X Receptor α Activity. Lipids. 2018 Jan;53(1):41-52. doi: 10.1002/lipd.12002. Epub 2018 Feb 15. PubMed PMID: 29446839.

[3] Ganesan P, Noda K, Manabe Y, Ohkubo T, Tanaka Y, Maoka T, Sugawara T, Hirata T. Siphonaxanthin, a marine carotenoid from green algae, effectively induces apoptosis in human leukemia (HL-60) cells. Biochim Biophys Acta. 2011 May;1810(5):497-503. doi: 10.1016/j.bbagen.2011.02.008. Epub 2011 Mar 1. PubMed PMID: 21371530.

[4] Li ZS, Noda K, Fujita E, Manabe Y, Hirata T, Sugawara T. The green algal carotenoid siphonaxanthin inhibits adipogenesis in 3T3-L1 preadipocytes and the accumulation of lipids in white adipose tissue of KK-Ay mice. J Nutr. 2015 Mar;145(3):490-8. doi: 10.3945/jn.114.200931. Epub 2014 Dec 24. PubMed PMID: 25733464.

[5] Manabe Y, Takii Y, Sugawara T. Siphonaxanthin, a carotenoid from green algae, suppresses advanced glycation end product-induced inflammatory responses. J Nat Med. 2019 Aug 20. doi: 10.1007/s11418-019-01354-z. [Epub ahead of print] PubMed PMID: 31432315.

6: Wang W, Qin X, Sang M, Chen D, Wang K, Lin R, Lu C, Shen JR, Kuang T. Spectral and functional studies on siphonaxanthin-type light-harvesting complex of photosystem II from Bryopsis corticulans. Photosynth Res. 2013 Nov;117(1-3):267-79. doi: 10.1007/s11120-013-9808-3. Epub 2013 Mar 12. PubMed PMID: 23479128.7: Li ZS, Zheng JW, Manabe Y, Hirata T, Sugawara T. Anti-Obesity Properties of the Dietary Green Alga, Codium cylindricum, in High-Fat Diet-Induced Obese Mice. J Nutr Sci Vitaminol (Tokyo). 2018;64(5):347-356. doi: 10.3177/jnsv.64.347. PubMed PMID: 30381625.8: Ganesan P, Matsubara K, Ohkubo T, Tanaka Y, Noda K, Sugawara T, Hirata T. Anti-angiogenic effect of siphonaxanthin from green alga, Codium fragile. Phytomedicine. 2010 Dec 1;17(14):1140-4. doi: 10.1016/j.phymed.2010.05.005. Epub 2010 Jul 16. PubMed PMID: 20637577.9: Manabe Y, Ichihara M, Fukuda K, Tomonaga N, Li ZS, Yamanashi Y, Suzuki H, Takada T, Matsuo M, Sugawara T. Niemann-Pick C1-like 1 Promotes Intestinal Absorption of Siphonaxanthin. Lipids. 2019 Oct 1. doi: 10.1002/lipd.12194. [Epub ahead of print] PubMed PMID: 31574565.10: Akimoto S, Yokono M, Higuchi M, Tomo T, Takaichi S, Murakami A, Mimuro M. Solvent effects on excitation relaxation dynamics of a keto-carotenoid, siphonaxanthin. Photochem Photobiol Sci. 2008 Oct;7(10):1206-9. doi: 10.1039/b802658k. Epub 2008 Aug 6. PubMed PMID: 18846284.1

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