1420-08-2|Desacetamidocolchicine|Benzo(a)heptalen-9(5H)-one, 6,7-dihydro-1,2,3,10-tetramethoxy-|-范德生物科技公司

Desacetamidocolchicine

NMR下载 COA and HPLC MSDS下载
names：
Benzo(a)heptalen-9(5H)-one, 6,7-dihydro-1,2,3,10-tetramethoxy-
CAS号：
1420-08-2
MDL Number：
MF(分子式)： C20H22O5 MW(分子量)： 342.39
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

货品编码	规格	纯度	价格 (¥)	现价(¥)	特价(¥)	库存描述	数量	总计 (¥)

大包装询价提供各种包装，敬请垂询
收藏商品商品点评加入购物车立即购买

快速询价

收起

你想询价的产品

*产品名称：

CAS号：

产品编号：

需求描述：

请准确填写您的联系方式，以便为您提供最好的服务。

*公司名称：

*电子邮箱：

联系人：

*电话：

*验证码：

询价

中文别名	Desacetamidocolchicine
英文别名	Desacetamidocolchicine; Deacetylaminocolchicine; DAAC
CAS号	1420-08-2
Inchi	InChI=1S/C20H22O5/c1-22-16-9-8-14-12(10-15(16)21)6-5-7-13-11-17(23-2)19(24-3)20(25-4)18(13)14/h8-11H,5-7H2,1-4H3
InchiKey	IPDJRYUVROTJTO-UHFFFAOYSA-N
分子式 Formula	C20H22O5
分子量 Molecular Weight	342.39
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Desacetamidocolchicine(CAS:1420-08-2):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Desacetamidocolchicine (DAAC) is a colchicine analogue that lacks the acetamido side chain in the ring-B of colchicine. Unlike colchicine, it binds to tubulin very quickly, and yet it has powerful antimitotic properties. It has been demonstrated that the beta-tubulin isoforms differ significantly in their interactions with colchicine.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Roychowdhury M, Sarkar N, Manna T, Bhattacharyya S, Sarkar T, Basusarkar P, Roy S, Bhattacharyya B. Sulfhydryls of tubulin. A probe to detect conformational changes of tubulin. Eur J Biochem. 2000 Jun;267(12):3469-76. PubMed PMID: 10848962.

[2]Banerjee A, D'Hoore A, Engelborghs Y. Interaction of desacetamidocolchicine, a fast binding analogue of colchicine with isotypically pure tubulin dimers alpha beta II, alpha beta III, and alpha beta IV. J Biol Chem. 1994 Apr 8;269(14):10324-9. PubMed PMID: 8144613.

[3] Maity SN, Bhattacharyya B. Properties of B-ring analogues of colchicine. FEBS Lett. 1987 Jun 22;218(1):102-6. PubMed PMID: 3595855.

[4] Ghosh Choudhury G, Maity S, Bhattacharyya B, Biswas BB. B-ring of colchicine and its role in taxol-induced tubulin polymerization. FEBS Lett. 1986 Mar 3;197(1-2):31-4. PubMed PMID: 2868923.

[5] Choudhury GG, Banerjee A, Bhattacharyya B, Biswas BB. Interaction of colchicine analogues with purified tubulin. FEBS Lett. 1983 Sep 5;161(1):55-9. PubMed PMID: 6884527.

6: Ray K, Bhattacharyya B, Biswas BB. Role of B-ring of colchicine in its binding to tubulin. J Biol Chem. 1981 Jun 25;256(12):6241-4. PubMed PMID: 7240202.

对不起，暂无产品评价！

MSDS

SDS 1.0 中文

展开

SDS 1.0 英文

展开