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118395-73-6
  • Chloroorienticin A

  • names:

    N/A

  • CAS号:

    118395-73-6

    MDL Number:
  • MF(分子式): C73H88Cl2N10O26 MW(分子量): 1592.45
  • EINECS: Reaxys Number:
  • Pubchem ID: Brand:BIOFOUNT
Chloroorienticin A
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中文别名 Chloroorienticin A
英文别名 Chloroorienticin A; A82846B; A 82846B; A-82846B;
CAS号 118395-73-6
Inchi InChI=1S/C73H88Cl2N10O26/c1-26(2)14-38(79-7)64(96)84-54-56(91)30-9-12-42(36(74)16-30)106-44-18-32-19-45(60(44)111-71-61(58(93)57(92)46(25-86)108-71)110-49-24-73(6,78)63(95)28(4)105-49)107-43-13-10-31(17-37(43)75)59(109-48-23-72(5,77)62(94)27(3)104-48)55-69(101)83-53(70(102)103)35-20-33(87)21-41(89)50(35)34-15-29(8-11-40(34)88)51(66(98)85-55)82-67(99)52(32)81-65(97)39(22-47(76)90)80-68(54)100/h8-13,15-21,26-28,38-39,46,48-49,51-59,61-63,71,79,86-89,91-95H,14,22-25,77-78H2,1-7H3,(H2,76,90)(H,80,100)(H,81,97)(H,82,99)(H,83,101)(H,84,96)(H,85,98)(H,102,103)/t27-,28-,38+,39-,46+,48-,49-,51+,52+,53-,54+,55-,56+,57+,58+,59+,61+,62-,63-,71-,72-,73-/m0/s1
InchiKey XJHXLMVKYIVZTE-ZUDYGFIZSA-N
分子式 Formula C73H88Cl2N10O26
分子量 Molecular Weight 1592.45
溶解度Solubility
性状 Solid powder
储藏条件 Storage conditions Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).
产品说明 Chloroorienticin A(CAS:118395-73-6):仅限应用于工业或者科学研究过程中非医疗目的,不应用于人类或动物的临床诊断以及治过程疗,该产品非药用,非食用。
IntroductionChloroorienticin A is a glycopeptide antibiotic.
Application1
Application2
Application3
警示图
危险性 Warning
危险性警示
安全声明
安全防护
备注
[1]Allen NE, LeTourneau DL, Hobbs JN Jr, Thompson RC. Hexapeptide derivatives of glycopeptide antibiotics: tools for mechanism of action studies. Antimicrob Agents Chemother. 2002 Aug;46(8):2344-8. PubMed PMID: 12121903; PubMed Central PMCID: PMC127376.
[2]Pavlov AIu, Preobrazhenskaia MN. [Chemical modification of glycopeptide antibiotics]. Bioorg Khim. 1998 Sep;24(9):644-62. Review. Russian. PubMed PMID: 9813730.
[3] Rodriguez MJ, Snyder NJ, Zweifel MJ, Wilkie SC, Stack DR, Cooper RD, Nicas TI, Mullen DL, Butler TF, Thompson RC. Novel glycopeptide antibiotics: N-alkylated derivatives active against vancomycin-resistant enterococci. J Antibiot (Tokyo). 1998 Jun;51(6):560-9. PubMed PMID: 9711219.
[4] LeTourneau DL, Allen NE. Use of capillary electrophoresis to measure dimerization of glycopeptide antibiotics. Anal Biochem. 1997 Mar 1;246(1):62-6. PubMed PMID: 9056183.
[5] Allen NE, LeTourneau DL, Hobbs JN Jr. Molecular interactions of a semisynthetic glycopeptide antibiotic with D-alanyl-D-alanine and D-alanyl-D-lactate residues. Antimicrob Agents Chemother. 1997 Jan;41(1):66-71. PubMed PMID: 8980756; PubMed Central PMCID: PMC163661.
6: Nicas TI, Mullen DL, Flokowitsch JE, Preston DA, Snyder NJ, Zweifel MJ, Wilkie SC, Rodriguez MJ, Thompson RC, Cooper RD. Semisynthetic glycopeptide antibiotics derived from LY264826 active against vancomycin-resistant enterococci. Antimicrob Agents Chemother. 1996 Sep;40(9):2194-9. PubMed PMID: 8878606; PubMed Central PMCID: PMC163498.7: Cooper RD, Snyder NJ, Zweifel MJ, Staszak MA, Wilkie SC, Nicas TI, Mullen DL, Butler TF, Rodriguez MJ, Huff BE, Thompson RC. Reductive alkylation of glycopeptide antibiotics: synthesis and antibacterial activity. J Antibiot (Tokyo). 1996 Jun;49(6):575-81. PubMed PMID: 8698642.8: Linsdell H, Toiron C, Bruix M, Rivas G, Menéndez M. Dimerization of A82846B, vancomycin and ristocetin: influence on antibiotic complexation with cell wall model peptides. J Antibiot (Tokyo). 1996 Feb;49(2):181-93. PubMed PMID: 8621360.9: Prowse WG, Kline AD, Skelton MA, Loncharich RJ. Conformation of A82846B, a glycopeptide antibiotic, complexed with its cell wall fragment: an asymmetric homodimer determined using NMR spectroscopy. Biochemistry. 1995 Jul 25;34(29):9632-44. PubMed PMID: 7626632.10: Ena J, Houston A, Wenzel RP, Jones RN. Trends in gram-positive bloodstream organism resistance: a seven-year audit of five glycopeptides and other drugs at a large university hospital. J Chemother. 1993 Feb;5(1):17-21. PubMed PMID: 8459260.1
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