128022-93-5|Protein kinase inhibitor peptide|L-Isoleucine, L-threonyl-L-threonyl-L-tyrosyl-L-alanyl-L-alpha-aspartyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-serylglycyl-L-arginyl-L-threonylglycyl-L-arginyl-L-arginyl-L-asparaginyl-L-alanyl-|-范德生物科技公司

Protein kinase inhibitor peptide

NMR下载 COA and HPLC MSDS下载
names：
L-Isoleucine, L-threonyl-L-threonyl-L-tyrosyl-L-alanyl-L-alpha-aspartyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-serylglycyl-L-arginyl-L-threonylglycyl-L-arginyl-L-arginyl-L-asparaginyl-L-alanyl-
CAS号：
128022-93-5
MDL Number：
MF(分子式)： C84H136N28O27 MW(分子量)： 1970.18
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

货品编码	规格	纯度	价格 (¥)	现价(¥)	特价(¥)	库存描述	数量	总计 (¥)

大包装询价提供各种包装，敬请垂询
收藏商品商品点评加入购物车立即购买

快速询价

收起

你想询价的产品

*产品名称：

CAS号：

产品编号：

需求描述：

请准确填写您的联系方式，以便为您提供最好的服务。

*公司名称：

*电子邮箱：

联系人：

*电话：

*验证码：

询价

中文别名	L-Isoleucine, L-threonyl-L-threonyl-L-tyrosyl-L-alanyl-L-alpha-aspartyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-serylglycyl-L-arginyl-L-threonylglycyl-L-arginyl-L-arginyl-L-asparaginyl-L-alanyl-
英文别名	Protein kinase inhibitor peptide; PKIP;
CAS号	128022-93-5
SMILES	CC[C@H](C)[C@@H](C(O)=O)NC([C@H](C)NC([C@H](CC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC(CNC([C@H]([C@H](O)C)NC([C@H](CCCNC(N)=N)NC(CNC([C@H](CO)NC([C@H](C)NC([C@H]([C@@H](C)CC)NC([C@H](CC1=CC=CC=C1)NC([C@H](CC(O)=O)NC([C@H](C)NC([C@H](CC2=CC=C(O)C=C2)NC([C@H]([C@H](O)C)NC([C@H]([C@H](O)C)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Inchi
InchiKey	ZLKNTGQAQQSIFV-HQAKDUOCSA-N
分子式 Formula	C84H136N28O27
分子量 Molecular Weight	1970.18
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Protein kinase inhibitor peptide(CAS:128022-93-5):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Protein kinase inhibitor peptide corresponds to the inhibitory domain of the heat-stable protein kinase inhibitor.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Dalton GD, Dewey WL. Protein kinase inhibitor peptide (PKI): a family of endogenous neuropeptides that modulate neuronal cAMP-dependent protein kinase function. Neuropeptides. 2006 Feb;40(1):23-34. Epub 2006 Jan 26. Review. PubMed PMID: 16442618.

[2]Olah GA, Mitchell RD, Sosnick TR, Walsh DA, Trewhella J. Solution structure of the cAMP-dependent protein kinase catalytic subunit and its contraction upon binding the protein kinase inhibitor peptide. Biochemistry. 1993 Apr 13;32(14):3649-57. PubMed PMID: 8385485.

[3] Taffs RE, Sitkovsky MV. Modulation of the effector functions of cytolytic T-lymphocytes with synthetic peptide inhibitors of protein kinases. J Pharm Sci. 1992 Jan;81(1):37-44. PubMed PMID: 1619567.

[4] Glass DB, Feller MJ, Levin LR, Walsh DA. Structural basis for the low affinities of yeast cAMP-dependent and mammalian cGMP-dependent protein kinases for protein kinase inhibitor peptides. Biochemistry. 1992 Feb 18;31(6):1728-34. PubMed PMID: 1310617.

[5] Godwin AJ, Green LM, Walsh MP, McDonald JR, Walsh DA, Fletcher WH. In situ regulation of cell-cell communication by the cAMP-dependent protein kinase and protein kinase C. Mol Cell Biochem. 1993 Nov;127-128:293-307. PubMed PMID: 7935358.

6: Olsen SR, Uhler MD. Affinity purification of the C alpha and C beta isoforms of the catalytic subunit of cAMP-dependent protein kinase. J Biol Chem. 1989 Nov 5;264(31):18662-6. PubMed PMID: 2553718.7: Kurokawa H, Kato K, Iwanaga T, Sugi T, Sudo A, Kobayashi K, Gong H, Takemae H, Recuenco FC, Horimoto T, Akashi H. Identification of Toxoplasma gondii cAMP dependent protein kinase and its role in the tachyzoite growth. PLoS One. 2011;6(7):e22492. doi: 10.1371/journal.pone.0022492. Epub 2011 Jul 20. PubMed PMID: 21799871; PubMed Central PMCID: PMC3140512.8: Ruth P, Kamm S, Nau U, Pfeifer A, Hofmann F. A cGMP kinase mutant with increased sensitivity to the protein kinase inhibitor peptide PKI(5-24). Biol Chem. 1996 Jul-Aug;377(7-8):513-20. PubMed PMID: 8922286.9: Fernandez A, Mery J, Vandromme M, Basset M, Cavadore JC, Lamb NJ. Effective intracellular inhibition of the cAMP-dependent protein kinase by microinjection of a modified form of the specific inhibitor peptide PKi in living fibroblasts. Exp Cell Res. 1991 Aug;195(2):468-77. PubMed PMID: 2070829.10: Zimmermann LJ, Lee WS, Smith BT, Post M. Cyclic AMP-dependent protein kinase does not regulate CTP:phosphocholine cytidylyltransferase activity in maturing type II cells. Biochim Biophys Acta. 1994 Feb 10;1211(1):44-50. PubMed PMID: 8123681.1

对不起，暂无产品评价！

MSDS

SDS 1.0 中文

展开

SDS 1.0 英文

展开