123564-61-4|Limonin glucoside|Limonin glucoside|-范德生物科技公司

Limonin glucoside

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names：
Limonin glucoside
CAS号：
123564-61-4
MDL Number：
MF(分子式)： C32H42O14 MW(分子量)： 650.67
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	(3'S,4aR,6aS,8aS,9S,10S,12aS,12bR)-10-((S)-furan-3-yl(((2R,3R,4R,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)-6,6,8a,10-tetramethyl-3,8-dioxodecahydro-1H,3H,6H-spiro[naphtho[1',2'3,4]furo[3,2-c]pyran-9,2'-oxirane]-3'-carboxylic acid
英文别名	CCRIS 6986; CCRIS6986; CCRIS-6986; Limonin glucoside
CAS号	123564-61-4
SMILES	OC[C@@H]1O[C@@H](O[C@H]([C@]2([C@]3([C@]4(C(C[C@@H]5C(C)(O[C@@H]6CC(OC[C@@]56[C@@H]4CC2)=O)C)=O)C)[C@H](O3)C(O)=O)C)c7ccoc7)[C@H](O)[C@H](O)[C@@H]1O
Inchi	InChI=1S/C32H42O14/c1-28(2)17-9-18(34)30(4)16(31(17)13-42-20(35)10-19(31)45-28)5-7-29(3,32(30)25(46-32)26(39)40)24(14-6-8-41-12-14)44-27-23(38)22(37)21(36)15(11-33)43-27/h6,8,12,15-17,19,21-25,27,33,36-38H,5,7,9-11,13H2,1-4H3,(H,39,40)/t15-,16+,17+,19+,21+,22+,23+,24-,25+,27-,29-,30+,31+,32-/m0/s1
InchiKey	FYIKIBQJAJRKQM-BPHZWCSFSA-N
分子式 Formula	C32H42O14
分子量 Molecular Weight	650.67
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Limonin glucoside(CAS:123564-61-4):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Limonin glucoside is found in citrus fruits. It induces apoptosis in colon adenocarcinoma cells, inhibits expression of HIV-1 and HTLV-1 in infected cells, and exhibits larvicidal activity against species of Aedes.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Chidambara Murthy KN, Jayaprakasha GK, Kumar V, Rathore KS, Patil BS. Citrus limonin and its glucoside inhibit colon adenocarcinoma cell proliferation through apoptosis. J Agric Food Chem. 2011 Mar 23;59(6):2314-23. doi: 10.1021/jf104498p. Epub 2011 Feb 2[1]PubMed PMID: 21338095.

[2]Somasundaram S, Price J, Pearce K, Shuck R, Jayaprakasha GK, Patil B. Citrus limonin lacks the antichemotherapeutic effect in human models of breast cancer. J Nutrigenet Nutrigenomics. 2012;5(2):106-14. Epub 2012 Aug 17. PubMed PMID: 22907263.

[3] Breksa AP 3rd, Manners GD. Evaluation of the antioxidant capacity of limonin, nomilin, and limonin glucoside. J Agric Food Chem. 2006 May 31;54(11):3827-31. PubMed PMID: 16719503.

[4] Zunino SJ, Storms DH, Freytag TL, Adkins YC, Bonnel EL, Woodhouse LR, Breksa AP 3rd, Manners GD, Mackey BE, Kelley DS. Dietary supplementation with purified citrus limonin glucoside does not alter ex vivo functions of circulating T lymphocytes or monocytes in overweight/obese human adults. Nutr Res. 2016 Jan;36(1):24-30. doi: 10.1016/j.nutres.2015.10.011. Epub 2015 Oct 31. PubMed PMID: 26773778.

[5] Breksa AP 3rd, Dragull K, Wong RY. Isolation and identification of the first C-17 limonin epimer, epilimonin. J Agric Food Chem. 2008 Jul 23;56(14):5595-8. doi: 10.1021/jf800473z. Epub 2008 Jun 20. PubMed PMID: 18564847.

6: Perez JL, Jayaprakasha GK, Valdivia V, Munoz D, Dandekar DV, Ahmad H, Patil BS. Limonin methoxylation influences the induction of glutathione S-transferase and quinone reductase. J Agric Food Chem. 2009 Jun 24;57(12):5279-86. doi: 10.1021/jf803712a. PubMed PMID: 19480426; PubMed Central PMCID: PMC2730739.7: Breksa AP 3rd, Ibarra P Jr. Colorimetric method for the estimation of total limonoid aglycones and glucoside contents in citrus juices. J Agric Food Chem. 2007 Jun 27;55(13):5013-7. Epub 2007 Jun 2. PubMed PMID: 17542603.8: Tian Q, Kent KD, Bomser JA, Schwartz SJ. Characterization of limonin glucoside metabolites from human prostate cell culture medium using high-performance liquid chromatography/electrospray ionization mass spectrometry and tandem mass spectrometry. Rapid Commun Mass Spectrom. 2004;18(24):3099-104. PubMed PMID: 15565733.9: Braddock RJ, Bryan CR. Extraction parameters and capillary electrophoresis analysis of limonin glucoside and phlorin in citrus byproducts. J Agric Food Chem. 2001 Dec;49(12):5982-8. PubMed PMID: 11743796.10: Miller EG, Gonzales-Sanders AP, Couvillon AM, Wright JM, Hasegawa S, Lam LK. Inhibition of hamster buccal pouch carcinogenesis by limonin 17-beta-D-glucopyranoside. Nutr Cancer. 1992;17(1):1-7. PubMed PMID: 1574440.1

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