84600-89-5|Factumycin|Factumycin|-范德生物科技公司

Factumycin

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names：
Factumycin
CAS号：
84600-89-5
MDL Number：
MF(分子式)： C44H62N2O10 MW(分子量)： 778.984
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	2H-Pyran-2-acetamide, N-((2E,4E,6S,7S,9S,10E,12E,14E,16E)-18-(1,2-dihydro-4-hydroxy-1-methyl-2-oxo-3-pyridinyl)-8,9-dihydroxy-6-methoxy-5,7,17-trimethyl-18-oxo-2,4,10,12,14,16-octadecahexaenyl)-alpha-ethyltetrahydro-2,4-dihydroxy-5,5-dimethyl-6-((1E,3Z)-1,3-pentadienyl)-, (alphaS,2S,4S,6S)-
英文别名	Factumycin; Antibiotic A 40A
CAS号	84600-89-5
Inchi	InChI=1S/C44H62N2O10/c1-10-12-16-24-36-43(6,7)35(49)28-44(54,56-36)32(11-2)41(52)45-26-20-19-22-30(4)40(55-9)31(5)39(51)34(48)23-18-15-13-14-17-21-29(3)38(50)37-33(47)25-27-46(8)42(37)53/h10,12-25,27,31-32,34-36,39-40,47-49,51,54H,11,26,28H2,1-9H3,(H,45,52)/b12-10-,15-13+,17-14+,20-19+,23-18+,24-16+,29-21+,30-22+/t31-,32+,34-,35-,36-,39?,40+,44-/m0/s1
InchiKey	HMBDLBWGDMNPDW-DQTCXKJJSA-N
分子式 Formula	C44H62N2O10
分子量 Molecular Weight	778.984
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Factumycin(CAS:84600-89-5):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Factumycin is an antibiotic from Streptomyces lavendulae.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Gullo VP, Zimmerman SB, Dewey RS, Hensens O, Cassidy PJ, Oiwa R, Omura S. Factumycin, a new antibiotic (A40A): fermentation, isolation and antibacterial spectrum. J Antibiot (Tokyo). 1982 Dec;35(12):1705-7. PubMed PMID: 7166535.

[2]Gui C, Li Q, Mo X, Qin X, Ma J, Ju J. Discovery of a new family of Dieckmann cyclases essential to tetramic acid and pyridone-based natural products biosynthesis. Org Lett. 2015 Feb 6;17(3):628-31. doi: 10.1021/ol5036497. Epub 2015 Jan 26. PubMed PMID: 25621700.

[3] Kakeya H, Morishita M, Ikeno A, Kobinata K, Yano T, Osada H. Factumycin and its new derivative RK-1009 enhance threonine-phosphorylation of a 60-kDa protein in Streptomyces griseus. J Antibiot (Tokyo). 1998 Oct;51(10):963-6. PubMed PMID: 9917012.

[4] Charousová I, Medo J, Hleba L, Javoreková S. Streptomyces globosus DK15 and Streptomyces ederensis ST13 as new producers of factumycin and tetrangomycin antibiotics. Braz J Microbiol. 2018 Oct - Dec;49(4):816-822. doi: 10.1016/j.bjm.2017.12.007. Epub 2018 Mar 1. PubMed PMID: 29705162; PubMed Central PMCID: PMC6175699.

[5] Maeda H, Bordner J, Cullen W, Huang L, Jefson M, Kaneda K, Niki K, Nishiyama S, Tone J, Whipple E. [UK-69,753, a new antibiotic related to efrotomycin and factumycin (A40A)]. Jpn J Antibiot. 1988 May;41(5):604. Japanese. PubMed PMID: 3216485.

6: Jefson MR, Bordner J, Reese CP, Whipple EB. UK-69,753, a novel member of the efrotomycin family of antibiotics. II. Structure determination and biological activity. J Antibiot (Tokyo). 1989 Nov;42(11):1610-8. PubMed PMID: 2584145.7: Pacey MS, Jefson MR, Huang LH, Cullen WP, Maeda H, Tone J, Nishiyama S, Kaneda K, Ishiguro M. UK-69,753, a novel member of the efrotomycin family of antibiotics. I. Taxonomy of the producing organism, fermentation and isolation. J Antibiot (Tokyo). 1989 Oct;42(10):1453-9. PubMed PMID: 2808132.

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