977-35-5|Epiandrosterone Sulfate|(3S,5S,9S,10S,13S,14S)-10,13-dimethyl-17-oxohexadecahydro-1H-cyclopenta[a]phenanthren-3-yl hydrogen sulfate|-范德生物科技公司

Epiandrosterone Sulfate

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names：
(3S,5S,9S,10S,13S,14S)-10,13-dimethyl-17-oxohexadecahydro-1H-cyclopenta[a]phenanthren-3-yl hydrogen sulfate
CAS号：
977-35-5
MDL Number：
MF(分子式)： C19H30O5S MW(分子量)： 370.504
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	Epiandrosterone Sulfate
英文别名	Epiandrosterone Sulfate, Epiandrosterone, Epiandrosterone 16-bromo, Epiandrosterone 16 bromo,
CAS号	977-35-5
SMILES	C[C@]12CC[C@H](OS(=O)(O)=O)C[C@]1([H])CCC3[C@]2([H])CC[C@@]4(C)[C@@]3([H])CCC4=O
Inchi	InChI=1S/C19H30O5S/c1-18-9-7-13(24-25(21,22)23)11-12(18)3-4-14-15-5-6-17(20)19(15,2)10-8-16(14)18/h12-16H,3-11H2,1-2H3,(H,21,22,23)/t12-,13-,14?,15-,16-,18-,19-/m0/s1
InchiKey	ZMITXKRGXGRMKS-DDCNXBGYSA-N
分子式 Formula	C19H30O5S
分子量 Molecular Weight	370.504
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	White to off-white crystalline powder.
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Epiandrosterone Sulfate(CAS:977-35-5 ):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Epiandrosterone Sulfate is a steroid hormone with weak androgenic activity. Epiandrosterone is naturally produced by the enzyme 5α-reductase from the adrenal hormone DHEA.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Sánchez-Guijo A, Oji V, Hartmann MF, Traupe H, Wudy SA. Simultaneous quantification of cholesterol sulfate, androgen sulfates, and progestagen sulfates in human serum by LC-MS/MS. J Lipid Res. 2015 Sep;56(9):1843-5[1]doi: 10.1194/jlr.D061499. Epub 2015 Aug 2. PubMed PMID: 26239050; PubMed Central PMCID: PMC4548788.

[2]Livshits G, Macgregor AJ, Gieger C, Malkin I, Moayyeri A, Grallert H, Emeny RT, Spector T, Kastenmüller G, Williams FM. An omics investigation into chronic widespread musculoskeletal pain reveals epiandrosterone sulfate as a potential biomarker. Pain. 2015 Oct;156(10):1845-51. doi: 10.1097/j.pain.0000000000000200. PubMed PMID: 25915148; PubMed Central PMCID: PMC4770329.

[3] Lewis JG, Bason LM, Elder PA. Production and characterization of monoclonal antibodies to dehydroepiandrosterone sulfate: application to direct enzyme-linked immunosorbent assays of dehydroepiandrosterone sulfate and androsterone/epiandrosterone sulfates in plasma. Steroids. 1996 Dec;61(12):682-7. PubMed PMID: 8987136.

[4] Dury AY, Ke Y, Gonthier R, Isabelle M, Simard JN, Labrie F. Validated LC-MS/MS simultaneous assay of five sex steroid/neurosteroid-related sulfates in human serum. J Steroid Biochem Mol Biol. 2015 May;149:1-10. doi: 10.1016/j.jsbmb.2015.01.006. Epub 2015 Jan 13. PubMed PMID: 25595042.

[5] Sánchez-Guijo A, Neunzig J, Gerber A, Oji V, Hartmann MF, Schuppe HC, Traupe H, Bernhardt R, Wudy SA. Role of steroid sulfatase in steroid homeostasis and characterization of the sulfated steroid pathway: Evidence from steroid sulfatase deficiency. Mol Cell Endocrinol. 2016 Dec 5;437:142-153. doi: 10.1016/j.mce.2016.08.019. Epub 2016 Aug 13. PubMed PMID: 27531568.

6: Mitamura K, Setaka M, Shimada K, Honma S, Namiki M, Koh E, Mizokami A. Determination of sulfates of androsterone and epiandrosterone in human serum using isotope diluted liquid chromatography-electrospray ionization-mass spectrometry. Biomed Chromatogr. 2005 Dec;19(10):796-801. PubMed PMID: 15954157.7: Higashi T, Shibayama Y, Kawasaki I, Shimada K. Determination of salivary 17-ketosteroid sulfates using liquid chromatography-electrospray ionization-mass spectrometry. J Pharm Biomed Anal. 2007 Apr 11;43(5):1782-8. Epub 2007 Jan 8. PubMed PMID: 17257796.8: PLAGER JE. THE BINDING OF ANDROSTERONE SULFATE, ETHIOCHOLANOLONE SULFATE, AND DEHYDROISOANDROSTERONE SULFATE BY HUMAN PLASMA PROTEIN. J Clin Invest. 1965 Jul;4

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