1462-73-3|Dextroamphetamine HCl|(S)-1-phenylpropan-2-amine hydrochloride|-范德生物科技公司

Dextroamphetamine HCl

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names：
(S)-1-phenylpropan-2-amine hydrochloride
CAS号：
1462-73-3
MDL Number：
MF(分子式)： C9H14ClN MW(分子量)： 171.668
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Dextroamphetamine HCl
英文别名	Dextroamphetamine; NSC 73713; NSC-73713; NSC73713
CAS号	1462-73-3
Inchi	InChI=1S/C9H13N.ClH/c1-8(10)7-9-5-3-2-4-6-9;/h2-6,8H,7,10H2,1H3;1H/t8-;/m0./s1
InchiKey	SEVKYLYIYIKRSW-QRPNPIFTSA-N
分子式 Formula	C9H14ClN
分子量 Molecular Weight	171.668
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Dextroamphetamine HCl(CAS:1462-73-3 ):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Dextroamphetamine HCl was discontinued (DEA controlled substance). Dextroamphetamine is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children.
Application1
Application2
Application3

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危险性	Warning
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安全声明
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备注

[1]Roberts JK, Cook SF, Stockmann C, Rollins DE, Wilkins DG, Sherwin CM. A Population Pharmacokinetic Analysis of Dextroamphetamine in the Plasma and Hair of Healthy Adults. Clin Drug Investig. 2015 Oct;35(10):633-43. doi: 10.1007/s40261-015-0323-5. PubMed PMID: 26329917; PubMed Central PMCID: PMC5572767.

[2]Ramtvedt BE, Aabech HS, Sundet K. Minimizing adverse events while maintaining clinical improvement in a pediatric attention-deficit/hyperactivity disorder crossover trial with dextroamphetamine and methylphenidate. J Child Adolesc Psychopharmacol. 2014 Apr;24(3):130-9. doi: 10.1089/cap.2013.0114. Epub 2014 Mar 25. PubMed PMID: 24666268; PubMed Central PMCID: PMC3993015.

[3] Check JH, Cohen R. Marked improvement of pain from long-term fibromyalgia with dextroamphetamine sulfate in a woman who failed to improve with conventional pharmacologic treatment. Clin Exp Obstet Gynecol. 2014;41(1):90-2. PubMed PMID: 24707694.

[4] Estrada A, Kelley AM, Webb CM, Athy JR, Crowley JS. Modafinil as a replacement for dextroamphetamine for sustaining alertness in military helicopter pilots. Aviat Space Environ Med. 2012 Jun;83(6):556-64. PubMed PMID: 22764609.

[5] Coghill DR, Caballero B, Sorooshian S, Civil R. A systematic review of the safety of lisdexamfetamine dimesylate. CNS Drugs. 2014 Jun;28(6):497-511. doi: 10.1007/s40263-014-0166-2. Review. PubMed PMID: 24788672; PubMed Central PMCID: PMC4057639.

6: McElroy SL, Hudson JI, Mitchell JE, Wilfley D, Ferreira-Cornwell MC, Gao J, Wang J, Whitaker T, Jonas J, Gasior M. Efficacy and safety of lisdexamfetamine for treatment of adults with moderate to severe binge-eating disorder: a randomized clinical trial. JAMA Psychiatry. 2015 Mar;72(3):235-46. doi: 10.1001/jamapsychiatry.2014.2162. PubMed PMID: 25587645.7: Makowski AL, Lindgren K, Locke JP. Visual side effects of scopolamine/ dextroamphetamine among parabolic fliers. Aviat Space Environ Med. 2011 Jul;82(7):683-8. PubMed PMID: 21748905.8: Childress AC, Brams M, Cutler AJ, Kollins SH, Northcutt J, Padilla A, Turnbow JM. The Efficacy and Safety of Evekeo, Racemic Amphetamine Sulfate, for Treatment of Attention-Deficit/Hyperactivity Disorder Symptoms: A Multicenter, Dose-Optimized, Double-Blind, Randomized, Placebo-Controlled Crossover Laboratory Classroom Study. J Child Adolesc Psychopharmacol. 2015 Jun;25(5):402-14. doi: 10.1089/cap.2014.0176. Epub 2015 Feb 18. PubMed PMID: 25692608; PubMed Central PMCID: PMC4491157.9: Sofuoglu M, Mooney M, Kosten T, Waters A, Hashimoto K. Minocycline attenuates subjective rewarding effects of dextroamphetamine in humans. Psychopharmacology (Berl). 2011 Jan;213(1):61-8. doi: 10.1007/s00213-010-2014-5. Epub 2010 Sep 14. PubMed PMID: 20838775; PubMed Central PMCID: PMC3014439.10: Perez-Reyes M, White WR, McDonald SA, Hicks RE. Interaction between ethanol and dextroamphetamine: effects on psychomotor performance. Alcohol Clin Exp Res. 1992 Feb;16(1):75-81. PubMed PMID: 1558306.1

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