115295-08-4|BC 197|BC 197|-范德生物科技公司

BC 197

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names：
BC 197
CAS号：
115295-08-4
MDL Number：
MF(分子式)： C60H81N11O17S MW(分子量)： 1260.42
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	(2S,5S,8R,11S,14S,17S,20S,24R)-11-((1H-indol-3-yl)methyl)-2-amino-8-(4-aminobutyl)-20-benzyl-5-((E)-buta-1,3-dien-1-yl)-24-((tert-butoxycarbonyl)amino)-14-butyl-1-(4-hydroxyphenyl)-3,9,12,15,18,21,23-heptaoxo-17-(2-oxo-2-(sulfooxy)ethyl)-4,7,10,13,16,19,22-heptaazahexacosan-26-oic acid
英文别名	BC 197; BC-197; BC197; Boc-asp-tyr(SO3H)-ahx-lys-trp-ahx-asp-phe-NH2;
CAS号	115295-08-4
Inchi	1S/C60H81N11O17S/c1-6-8-19-39(65-52(76)42(62)29-37-24-26-40(72)27-25-37)35-64-44(23-15-16-28-61)53(77)68-47(31-38-34-63-43-22-14-13-20-41(38)43)55(79)66-45(21-9-7-2)54(78)69-49(33-51(75)88-89(84,85)86)56(80)67-46(30-36-17-11-10-12-18-36)57(81)71-58(82)48(32-50(73)74)70-59(83)87-60(3,4)5/h6,8,10-14,17-20,22,24-27,34,39,42,44-49,63-64,72H,1,7,9,15-16,21,23,28-33,35,61-62H2,2-5H3,(H,65,76)(H,66,79)(H,67,80)(H,68,77)(H,69,78)(H,70,83)(H,73,74)(H,71,81,82)(H,84,85,86)/b19-8+/t39-,42-,44+,45-,46-,47-,48+,49-/m0/s1
InchiKey	KUPOETRFWZHGEM-LAZFATJSSA-N
分子式 Formula	C60H81N11O17S
分子量 Molecular Weight	1260.42
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	BC 197(CAS:115295-08-4):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	BC 197 is a selective CCK-B agonist.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Derrien M, McCort-Tranchepain I, Ducos B, Roques BP, Durieux C. Heterogeneity of CCK-B receptors involved in animal models of anxiety. Pharmacol Biochem Behav. 1994 Sep;49(1):133-4[1]PubMed PMID: 7816864.

[2]Léna I, Simon H, Roques BP, Daugé V. Opposing effects of two CCK(B) agonists on the retrieval phase of a two-trial memory task after systemic injection in the rat. Neuropharmacology. 1999 Apr;38(4):543-53. PubMed PMID: 10221758.

[3] Léna I, Roques BP, Durieux C. Dual modulation of dopamine release from anterior nucleus accumbens through cholecystokinin-B receptor subsites. J Neurochem. 1997 Jan;68(1):162-8. PubMed PMID: 8978722.

[4] Heidbreder C, Roques BP, De Witte P. Similar potencies of CCK-8 and its analogue BOC(Nle28;Nle31)CCK27-33 on the self-stimulation behaviour both are antagonized by a newly synthesized cyclic CCK analogue. Neuropeptides. 1989 Feb-Mar;13(2):89-94. PubMed PMID: 2739884.

[5] Derrien M, Durieux C, Roques BP. Antidepressant-like effects of CCKB antagonists in mice: antagonism by naltrindole. Br J Pharmacol. 1994 Mar;111(3):956-60. PubMed PMID: 8019773; PubMed Central PMCID: PMC1910081.

6: Léna I, Dh tel H, Garbay C, Daugé V. Involvement of D2 dopamine receptors in the opposing effects of two CCK-B agonists in a spatial recognition memory task: role of the anterior nucleus accumbens. Psychopharmacology (Berl). 2001 Jan 1;153(2):170-9. PubMed PMID: 11205416.7: Durieux C, Derrien M, Maldonado R, Valverde O, Blommaert A, Fournié-Zaluski MC, Roques BP. CCK-B antagonists exhibit antidepressant-like effects and potentiate endogenous enkephalin analgesia. Correlation with in vivo binding affinities and brain penetration. Ann N Y Acad Sci. 1994 Mar 23;71

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