344768-30-5|UBP141|(2R,3S)-1-[(phenanthren-3-yl)carbonyl]piperazine-2,3-dicarboxylic acid|-范德生物科技公司

UBP141

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names：
(2R,3S)-1-[(phenanthren-3-yl)carbonyl]piperazine-2,3-dicarboxylic acid
CAS号：
344768-30-5
MDL Number：
MF(分子式)： C21H18N2O5 MW(分子量)： 378.38
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	(2R,3S)-1-[(phenanthren-3-yl)carbonyl]piperazine-2,3-dicarboxylic acid
英文别名	UBP141, UBP 141, UBP-141
CAS号	344768-30-5
Inchi	InChI=1S/C21H18N2O5/c24-19(23-10-9-22-17(20(25)26)18(23)21(27)28)14-8-7-13-6-5-12-3-1-2-4-15(12)16(13)11-14/h1-8,11,17-18,22H,9-10H2,(H,25,26)(H,27,28)/t17-,18+/m0/s1
InchiKey	VVUAQPXBYDYTDF-ZWKOTPCHSA-N
分子式 Formula	C21H18N2O5
分子量 Molecular Weight	378.38
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	UBP141(CAS:344768-30-5):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	UBP141 is a N-methyl-D-aspartate (NMDA) receptor antagonist.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Yamamoto H, Kamegaya E, Sawada W, Hasegawa R, Yamamoto T, Hagino Y, Takamatsu Y, Imai K, Koga H, Mishina M, Ikeda K. Involvement of the N-methyl-D-aspartate receptor GluN2D subunit in phencyclidine-induced motor impairment, gene expression, and increased Fos immunoreactivity. Mol Brain. 2013 Dec 16;

6:56. doi: 10.1186/1756-6606-6-56. PubMed PMID: 24330819; PubMed Central PMCID: PMC3878647.

[3]Wang M, Chazot PL, Ali S, Duckett SF, Obrenovitch TP. Effects of NMDA receptor antagonists with different subtype selectivities on retinal spreading depression. Br J Pharmacol. 2012 Jan;165(1):235-44. doi: 10.1111/j.1476-5381.2011.01553.x. PubMed PMID: 21699507; PubMed Central PMCID: PMC3252980.

[4]Palygin O, Lalo U, Pankratov Y. Distinct pharmacological and functional properties of NMDA receptors in mouse cortical astrocytes. Br J Pharmacol. 2011 Aug;163(8):1755-66. doi: 10.1111/j.1476-5381.2011.01374.x. PubMed PMID: 21449975; PubMed Central PMCID: PMC3166701.

[5] Palygin O, Lalo U, Verkhratsky A, Pankratov Y. Ionotropic NMDA and P2X1/5 receptors mediate synaptically induced Ca2+ signalling in cortical astrocytes. Cell Calcium. 2010 Oct;48(4):225-31. doi: 10.1016/j.ceca.2010.09.004. PubMed PMID: 20926134.

5: Suárez F, Zhao Q, Monaghan DT, Jane DE, Jones S, Gibb AJ. Functional heterogeneity of NMDA receptors in rat substantia nigra pars compacta and reticulata neurones. Eur J Neurosci. 2010 Aug;32(3):359-67. doi: 10.1111/j.1460-9568.2010.07298.x. Epub 2010 Jul 6. PubMed PMID: 20618827; PubMed Central PMCID: PMC4177768.

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