121024-51-9|Tyrostatin|(2S)-2-((2S)-3-(4-hydroxyphenyl)-N-(1-(4-hydroxyphenyl)-3-oxopropan-2-yl)-2-(3-methylbutanamido)propanamido)-4-methylpentanamide|-范德生物科技公司

Tyrostatin

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names：
(2S)-2-((2S)-3-(4-hydroxyphenyl)-N-(1-(4-hydroxyphenyl)-3-oxopropan-2-yl)-2-(3-methylbutanamido)propanamido)-4-methylpentanamide
CAS号：
121024-51-9
MDL Number：
MF(分子式)： C29H39N3O6 MW(分子量)： 525.64
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	(2S)-2-((2S)-3-(4-hydroxyphenyl)-N-(1-(4-hydroxyphenyl)-3-oxopropan-2-yl)-2-(3-methylbutanamido)propanamido)-4-methylpentanamide
英文别名	Tyrostatin; N-Isovaleryl-tyrosyl-leucyl-tyrosinal;
CAS号	121024-51-9
Inchi	InChI=1S/C29H39N3O6/c1-18(2)13-26(28(30)37)32(22(17-33)15-20-5-9-23(34)10-6-20)29(38)25(31-27(36)14-19(3)4)16-21-7-11-24(35)12-8-21/h5-12,17-19,22,25-26,34-35H,13-16H2,1-4H3,(H2,30,37)(H,31,36)/t22?,25-,26-/m0/s1
InchiKey	LOHCSDORPLNBQQ-DDZRMCBLSA-N
分子式 Formula	C29H39N3O6
分子量 Molecular Weight	525.64
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Tyrostatin(CAS:121024-51-9):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Tyrostatin is a new peptide proteinase inhibitor of pepstatin-insensitive carboxyl proteinases; isolated from Kitasatosporia.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Wlodawer A, Li M, Gustchina A, Dauter Z, Uchida K, Oyama H, Goldfarb NE, Dunn BM, Oda K. Inhibitor complexes of the Pseudomonas serine-carboxyl proteinase. Biochemistry. 2001 Dec 25;40(51):15602-1[1]PubMed PMID: 11747435.

[2]Ito M, Dunn BM, Oda K. Substrate specificities of pepstatin-insensitive carboxyl proteinases from gram-negative bacteria. J Biochem. 1996 Oct;120(4):845-50. PubMed PMID: 8947851.

[3] Ito M, Narutaki S, Uchida K, Oda K. Identification of carboxyl residues in pepstatin-insensitive carboxyl proteinase from Pseudomonas sp. 101 that participate in catalysis and substrate binding. J Biochem. 1999 Jan;125(1):210-6. PubMed PMID: 9880819.

[4] Oda K, Nakatani H, Dunn BM. Substrate specificity and kinetic properties of pepstatin-insensitive carboxyl proteinase from Pseudomonas sp. No. 101. Biochim Biophys Acta. 1992 Apr 8;1120(2):208-14. PubMed PMID: 1562589.

[5] Oda K, Takahashi T, Tokuda Y, Shibano Y, Takahashi S. Cloning, nucleotide sequence, and expression of an isovaleryl pepstatin-insensitive carboxyl proteinase gene from Pseudomonas sp. 101. J Biol Chem. 1994 Oct 21;269(42):26518-24. PubMed PMID: 7929375.

6: Oda K, Ito M, Uchida K, Shibano Y, Fukuhara K, Takahashi S. Cloning and expression of an isovaleryl pepstatin-insensitive carboxyl proteinase gene from Xanthomonas sp. T-22. J Biochem. 1996 Sep;120(3):564-72. PubMed PMID: 8902622.7: Ezaki J, Takeda-Ezaki M, Oda K, Kominami E. Characterization of endopeptidase activity of tripeptidyl peptidase-I/CLN2 protein which is deficient in classical late infantile neuronal ceroid lipofuscinosis. Biochem Biophys Res Commun. 2000 Feb 24;268(3):904-8. PubMed PMID: 10679303.

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