1947-37-1|CCK-4|CCK-4, CCKB receptor agonist|-范德生物科技公司

CCK-4

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names：
CCK-4, CCKB receptor agonist
CAS号：
1947-37-1
MDL Number：
MF(分子式)： C29H36N6O6S MW(分子量)： 596.7
EINECS: Reaxys Number:
Pubchem ID:446569 Brand:BIOFOUNT

CCK-4, CCKB receptor agonist(1947-37-1)是一种选择性胆囊收缩素 B (CCKB) 受体激动剂，可以增加肥大细胞的分泌活性。CCK-4是一种焦虑剂，在体内和体外都有活性。

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询价

中文别名	CCK-4(1947-37-1);CCKB受体激动剂
英文别名	CCK-4, CCKB receptor agonist(1947-37-1);Tetragastrin; Gastrin tetrapeptide; Cholecystokinin tetrapeptide;
CAS号	1947-37-1
Inchi	InChI=1S/C29H36N6O6S/c1-42-12-11-22(33-27(39)20(30)14-18-16-32-21-10-6-5-9-19(18)21)28(40)35-24(15-25(36)37)29(41)34-23(26(31)38)13-17-7-3-2-4-8-17/h2-10,16,20,22-24,32H,11-15,30H2,1H3,(H2,31,38)(H,33,39)(H,34,41)(H,35,40)(H,36,37)/t20-,22-,23-,24-/m0/s1
InchiKey	RGYLYUZOGHTBRF-BIHRQFPBSA-N
分子式 Formula	C29H36N6O6S
分子量 Molecular Weight	596.7
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Store at -20°C. Store under desiccating conditions.

产品说明	CCK-4, CCKB receptor agonist(1947-37-1)是一种选择性胆囊收缩素 B (CCKB) 受体激动剂，可以增加肥大细胞的分泌活性。CCK-4是一种焦虑剂，在体内和体外都有活性。
Introduction	Tetragastrin(1947-37-1) is the C-terminal tetrapeptide of gastrin. It is the smallest peptide fragment of gastrin which has the same physiological and pharmacological activity as gastrin.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示	P264处理后彻底清洗+P280戴防护手套/穿防护服/戴防护眼罩/戴防护面具+P305如果进入眼睛+P351用水小心冲洗几分钟+P338取出隐形眼镜（如果有）并且易于操作,继续冲洗+P337如果眼睛刺激持续+P313获得医疗建议/护理
安全声明	H315 H319 H335
安全防护	P264 P302+P352 P304+P340 P305+P351+P338 P332+P313 P337+P313
备注

[1]Tenma T, Yodoya E, Tashima S, Fujita T, Murakami M, Yamamoto A, Muranishi S. Development of new lipophilic derivatives of tetragastrin: physicochemical characteristics and intestinal absorption of acyl-tetragastrin derivatives in rats. Pharm Res. 1993 Oct;10(10):1488-92. PubMed PMID: 8272412.

[2]Komuro Y, Ishihara K, Ohara S, Saigenji K, Hotta K. Effects of tetragastrin on mucus glycoprotein in rat gastric mucosal protection. Gastroenterol Jpn. 1992 Oct;27(5):597-603. PubMed PMID: 1385248.

[3] Tatsuta M, Iishi H, Yamamura H, Taniguchi H. Inhibition by tetragastrin of experimental carcinogenesis in rat colon: effect of wheat bran consumption. Int J Cancer. 1988 Feb 15;41(2):239-42. PubMed PMID: 2828245.

[4] Tatsuta M, Iishi H, Baba M, Taniguchi H. Effect of 6-hydroxydopamine on gastric carcinogenesis and tetragastrin inhibition of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats. Cancer Res. 1989 Aug 1;49(15):4199-203. PubMed PMID: 2501024.

[5] Tatsuta M, Iishi H, Yamamura H, Taniguchi H. Enhancement by propranolol of the inhibitory effect of tetragastrin on gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats. Cancer Res. 1987 Jan 1;47(1):111-4. PubMed PMID: 3791197.

6: Setoh K, Murakami M, Araki N, Fujita T, Yamamoto A, Muranishi S. Improvement of transdermal delivery of tetragastrin by lipophilic modification with fatty acids. J Pharm Pharmacol. 1995 Oct;47(10):808-11. PubMed PMID: 8583347.7: Komuro Y, Ishihara K, Kojima Y, Saigenji K, Hotta K. Distinct effects of tetragastrin in rat gastroduodenal mucosa on mucin content and mucosal protective action against histamine-induced injury. Dig Dis Sci. 1998 May;43(5):1050-6. PubMed PMID: 9590421.8: Tatsuta M, Yamamura H, Baba M, Yamamoto R, Iishi H, Taniguchi H. Inhibitory effect of prolonged administration of tetragastrin on experimentally induced intestinal metaplasia in Wistar rats. Cancer. 1988 May 15;61(10):2051-6. PubMed PMID: 3359403.9: Tatsuta M, Iishi H, Yamamura H, Yamamoto R, Taniguchi H. Enhancement by tetragastrin of experimental induction of gastric epithelium in the duodenum. Gut. 1989 Mar;30(3):311-5. PubMed PMID: 2707631; PubMed Central PMCID: PMC1378451.10: Tatsuta M, Iishi H, Baba M, Taniguchi H. Effect of ornithine decarboxylase inhibitor on tetragastrin treatment of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats. Int J Cancer. 1990 Feb 15;45(2):308-11. PubMed PMID: 2105911.1

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