213192-26-8|TBTC|Methyl 2-amino-6-(tert-butyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate|-范德生物科技公司

TBTC

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names：
Methyl 2-amino-6-(tert-butyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate
CAS号：
213192-26-8
MDL Number：
MF(分子式)： C14H21NO2S MW(分子量)： 267.38
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Methyl 2-amino-6-(tert-butyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate
英文别名	TBTC;
CAS号	213192-26-8
Inchi	InChI=1S/C14H21NO2S/c1-14(2,3)8-5-6-9-10(7-8)18-12(15)11(9)13(16)17-4/h8H,5-7,15H2,1-4H3
InchiKey	BYFPSGIBNPFZOY-UHFFFAOYSA-N
分子式 Formula	C14H21NO2S
分子量 Molecular Weight	267.38
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	TBTC(CAS:213192-26-8):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	TBTC is a selective retinoid X receptor α agonist. It acts by improving behavioral deficit in Alzheimer's disease model mice.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Vjecha MJ, Tiberi S, Zumla A. Accelerating the development of therapeutic strategies for drug-resistant tuberculosis. Nat Rev Drug Discov. 2018 Mar 23. doi: 10.1038/nrd.2018.28. [Epub ahead of print] PubMed PMID: 29567994.

[2]Saber HR, Tabatabaee SM, Abasian A, Jamali M, SalekMoghadam E, Hajibeigi B, Alavian SM, Mirrezaie SM. Incidence and Residual Risk of HIV, HBV and HCV Infections Among Blood Donors in Tehran. Indian J Hematol Blood Transfus. 2017 Sep;33(3):412-416. doi: 10.1007/s12288-016-0732-5. Epub 2016 Oct 1. PubMed PMID: 28824247; PubMed Central PMCID: PMC5544631.

[3] Mitra S, Srivastava A, Khandelwal S. Long term impact of the endocrine disruptor tributyltin on male fertility following a single acute exposure. Environ Toxicol. 2017 Oct;32(10):2295-2304. doi: 10.1002/tox.22446. Epub 2017 Jul 14. PubMed PMID: 28707438.

[4] Illathvalappil R, Dhavale VM, Bhange SN, Kurungot S. Nitrogen-doped graphene anchored with mixed growth patterns of CuPt alloy nanoparticles as a highly efficient and durable electrocatalyst for the oxygen reduction reaction in an alkaline medium. Nanoscale. 2017 Jul 6;9(26):9009-9017. doi: 10.1039/c7nr00697g. PubMed PMID: 28639678.

[5] Alsultan A, Savic R, Dooley KE, Weiner M, Whitworth W, Mac Kenzie WR, Peloquin CA; Tuberculosis Trials Consortium. Population Pharmacokinetics of Pyrazinamide in Patients with Tuberculosis. Antimicrob Agents Chemother. 2017 May 24;61(6). pii: e02625-16. doi: 10.1128/AAC.02625-16. Print 2017 Jun. PubMed PMID: 28289033; PubMed Central PMCID: PMC5444154.

6: Sterling TR, Scott NA, Miro JM, Calvet G, La Rosa A, Infante R, Chen MP, Benator DA, Gordin F, Benson CA, Chaisson RE, Villarino ME; Tuberculosis Trials Consortium, the AIDS Clinical Trials Group for the PREVENT TB Trial (TBTC Study 26ACTG 5259) The investigators of the TB Trials Consortium and the AIDS Clinical Trials Group for the PREVENT TB Trial are listed in the Supplement, item 17. Three months of weekly rifapentine and isoniazid for treatment of Mycobacterium tuberculosis infection in HIV-coinfected persons. AIDS. 2016 Jun 19;30(10):1607-15. doi: 10.1097/QAD.0000000000001098. PubMed PMID: 27243774; PubMed Central PMCID: PMC4899978.7: López-Gallardo E, Llobet L, Emperador S, Montoya J, Ruiz-Pesini E. Effects of Tributyltin Chloride on Cybrids with or without an ATP Synthase Pathologic Mutation. Environ Health Perspect. 2016 Sep;124(9):1399-405. doi: 10.1289/EHP182. Epub 2016 Apr 29. PubMed PMID: 27129022; PubMed Central PMCID: PMC5010394.8: Gyaltsen K, Gipson JD, Gyal L, Kyi T, Hicks AL, Pebley AR. Maternal health care seeking by rural Tibetan women: characteristics of women delivering at a newly-constructed birth center in western China. BMC Pregnancy Childbirth. 2015 Sep 22;1

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