156161-88-5|Snf 9007|(3S,6S,9S,15R,18S,21S)-21-amino-3-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)carbamoyl)-15-benzyl-6-butyl-18-(4-hydroxybenzyl)-9-((1-methyl-1H-indol-3-yl)methyl)-5,8,11,14,17,20-hexaoxo-4,7,10,13,16,19-hexaazatricosanedioic acid|-范德生物科技公司

Snf 9007

NMR下载 COA and HPLC MSDS下载
names：
(3S,6S,9S,15R,18S,21S)-21-amino-3-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)carbamoyl)-15-benzyl-6-butyl-18-(4-hydroxybenzyl)-9-((1-methyl-1H-indol-3-yl)methyl)-5,8,11,14,17,20-hexaoxo-4,7,10,13,16,19-hexaazatricosanedioic acid
CAS号：
156161-88-5
MDL Number：
MF(分子式)： C55H66N10O13 MW(分子量)： 1075.19
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	(3S,6S,9S,15R,18S,21S)-21-amino-3-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)carbamoyl)-15-benzyl-6-butyl-18-(4-hydroxybenzyl)-9-((1-methyl-1H-indol-3-yl)methyl)-5,8,11,14,17,20-hexaoxo-4,7,10,13,16,19-hexaazatricosanedioic acid
英文别名	Snf 9007; Snf-9007; Snf9007; Asp-tyr-D-phe-gly-trp-(N-Me)nle-asp-phe-NH2;
CAS号	156161-88-5
Inchi	InChI=1S/C55H66N10O13/c1-3-4-18-39(52(75)64-44(29-48(70)71)55(78)61-40(49(57)72)24-32-13-7-5-8-14-32)60-54(77)43(27-35-31-65(2)45-19-12-11-17-37(35)45)59-46(67)30-58-51(74)41(25-33-15-9-6-10-16-33)63-53(76)42(26-34-20-22-36(66)23-21-34)62-50(73)38(56)28-47(68)69/h5-17,19-23,31,38-44,66H,3-4,18,24-30,56H2,1-2H3,(H2,57,72)(H,58,74)(H,59,67)(H,60,77)(H,61,78)(H,62,73)(H,63,76)(H,64,75)(H,68,69)(H,70,71)/t38-,39-,40-,41+,42-,43-,44-/m0/s1
InchiKey	MEBJVRFUJPOFQA-GLEMDPEOSA-N
分子式 Formula	C55H66N10O13
分子量 Molecular Weight	1075.19
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Snf 9007(CAS:156161-88-5):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Snf 9007 is a cholecystokinin antagonist.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Roerig SC, Williams CL, Hruby VJ, Burks TF, Rosenfeld GC. Inhibition of adenylyl cyclase activity by the cholecystokinin analog SNF 9007 in neuroblastoma x glioma NG108-15 hybrid cells. Regul Pept. 1996 Jan 16;61(1):51-6. PubMed PMID: 8701027.

[2]Boteju LW, Nikiforovich GV, Haskell-Luevano C, Fang SN, Zalewska T, Stropova D, Yamamura HI, Hruby VJ. The use of topographical constraints in receptor mapping: investigation of the topographical requirements of the tryptophan 30 residue for receptor binding of Asp-Tyr-D-Phe-Gly-Trp-(N-Me)Nle-Asp-Phe-NH2 (SNF 9007), a cholecystokinin (26-33) analogue that binds to both CCK-B and delta-opioid receptors. J Med Chem. 1996 Sep 27;39(20):4120-4. PubMed PMID: 8831778.

[3] Rao RK, Levenson S, Fang SN, Hruby VJ, Yamamura HI, Porreca F. Characterization of SNF 9007, a novel cholecystokinin/opoid ligand in mouse ileum in vitro: evidence for involvement of cholecystokininA and cholecystokininB receptors in regulation of ion transport. J Pharmacol Exp Ther. 1994 Feb;268(2):1003-9. PubMed PMID: 8113956.

[4] Rao RK, Levenson S, Fang SN, Hruby VJ, Yamamura HI, Porreca F. Role of substance P in the regulation of ion transport by CCKA and CCKB receptors in mouse ileum. Ann N Y Acad Sci. 1994 Mar 23;71

[5]420-1. PubMed PMID: 7514373.

5: Williams CL, Rosenfeld GC, Dafny N, Fang SN, Hruby VJ, Bowden G, Cullinan CA, Burks TF. SNF9007: a novel analgesic that acts simultaneously at delta 1, delta 2 and mu opioid receptors. J Pharmacol Exp Ther. 1994 May;269(2):750-5. PubMed PMID: 8182541.

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