35418-52-1|Schizokinen|2-hydroxy-4-((3-(N-hydroxyacetamido)propyl)amino)-2-(2-((3-(N-hydroxyacetamido)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid|-范德生物科技公司

Schizokinen

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names：
2-hydroxy-4-((3-(N-hydroxyacetamido)propyl)amino)-2-(2-((3-(N-hydroxyacetamido)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid
CAS号：
35418-52-1
MDL Number：
MF(分子式)： C16H28N4O9 MW(分子量)： 420.41
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	2-hydroxy-4-((3-(N-hydroxyacetamido)propyl)amino)-2-(2-((3-(N-hydroxyacetamido)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid
英文别名	Schizokinen;
CAS号	35418-52-1
Inchi	InChI=1S/C16H28N4O9/c1-11(21)19(28)7-3-5-17-13(23)9-16(27,15(25)26)10-14(24)18-6-4-8-20(29)12(2)22/h27-29H,3-10H2,1-2H3,(H,17,23)(H,18,24)(H,25,26)
InchiKey	YILWWVUXGMGOAM-UHFFFAOYSA-N
分子式 Formula	C16H28N4O9
分子量 Molecular Weight	420.41
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Schizokinen(CAS:35418-52-1):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Schizokinen is a citrate-containing dihydroxamate and a siderophore produced by Bacillus megaterium and Anabaena sp.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Rudolf M, Stevanovic M, Kranzler C, Pernil R, Keren N, Schleiff E. Multiplicity and specificity of siderophore uptake in the cyanobacterium Anabaena sp. PCC 7120. Plant Mol Biol. 2016 Sep;92(1-2):57-69. doi: 10.1007/s11103-016-0495-2. Epub 2016 Jun 20. PubMed PMID: 27325117.

[2]Lammers PJ, Sanders-Loehr J. Active transport of ferric schizokinen in Anabaena sp. J Bacteriol. 1982 Jul;151(1):288-94. PubMed PMID: 6806241; PubMed Central PMCID: PMC220240.

[3] Storey EP, Boghozian R, Little JL, Lowman DW, Chakraborty R. Characterization of 'Schizokinen'; a dihydroxamate-type siderophore produced by Rhizobium leguminosarum IARI 917. Biometals. 2006 Dec;19(6):637-49. Epub 2006 Jun 7. PubMed PMID: 16758117.

[4] Nicolaisen K, Moslavac S, Samborski A, Valdebenito M, Hantke K, Maldener I, Muro-Pastor AM, Flores E, Schleiff E. Alr0397 is an outer membrane transporter for the siderophore schizokinen in Anabaena sp. strain PCC 7120. J Bacteriol. 2008 Nov;190(22):7500-7. doi: 10.1128/JB.01062-08. Epub 2008 Sep 19. PubMed PMID: 18805987; PubMed Central PMCID: PMC2576664.

[5] Fadeev EA, Luo M, Groves JT. Synthesis, structure, and molecular dynamics of gallium complexes of schizokinen and the amphiphilic siderophore acinetoferrin. J Am Chem Soc. 2004 Sep 29;126(38):12065-75. PubMed PMID: 15382941.

6: Goldman SJ, Lammers PJ, Berman MS, Sanders-Loehr J. Siderophore-mediated iron uptake in different strains of Anabaena sp. J Bacteriol. 1983 Dec;156(3):1144-50. PubMed PMID: 6227608; PubMed Central PMCID: PMC217960.7: Cuív PO, Keogh D, Clarke P, O'Connell M. FoxB of Pseudomonas aeruginosa functions in the utilization of the xenosiderophores ferrichrome, ferrioxamine B, and schizokinen: evidence for transport redundancy at the inner membrane. J Bacteriol. 2007 Jan;189(1):284-7. Epub 2006 Oct 20. PubMed PMID: 17056746; PubMed Central PMCID: PMC1797220.8: Byers BR, Powell MV, Lankford CE. Iron-chelating hydroxamic acid (schizokinen) active in initiation of cell division in Bacillus megaterium. J Bacteriol. 1967 Jan;93(1):286-94. PubMed PMID: 4960152; PubMed Central PMCID: PMC315000.9: Cuív PO, Clarke P, O'Connell M. Identification and characterization of an iron-regulated gene, chtA, required for the utilization of the xenosiderophores aerobactin, rhizobactin 1021 and schizokinen by Pseudomonas aeruginosa. Microbiology. 2006 Apr;152(Pt 4):945-54. PubMed PMID: 16549659.10: Mullis KB, Pollack JR, Neilands JB. Structure of schizokinen, an iron-transport compound from Bacillus megaterium. Biochemistry. 1971 Dec 21;10(26):4894-8. PubMed PMID: 4332462.1

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