71774-13-5|Rp-cAMPS TEA salt|(2R,6R,7S)-6-(6-amino-9H-purin-9-yl)-7-hydroxy-2-mercaptotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine 2-oxide, triethylammonium salt|-范德生物科技公司

Rp-cAMPS TEA salt

NMR下载 COA and HPLC MSDS下载
names：
(2R,6R,7S)-6-(6-amino-9H-purin-9-yl)-7-hydroxy-2-mercaptotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine 2-oxide, triethylammonium salt
CAS号：
71774-13-5
MDL Number：
MF(分子式)： C16H28N6O5PS MW(分子量)： 447.47
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	(2R,6R,7S)-6-(6-amino-9H-purin-9-yl)-7-hydroxy-2-mercaptotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine 2-oxide, triethylammonium salt
英文别名	Rp-cAMPS TEA salt; Rp cAMPS TEA salt; Rp-cAMPS TEA; Rp cAMPS TEA;
CAS号	71774-13-5
SMILES	S[P@@]1(OCC(O[C@@H](N2C=NC3=C(N)N=CN=C23)[C@H]4O)C4O1)=O.CC[NH+](CC)CC
Inchi	InChI=1S/C10H12N5O5PS.C6H15N/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(19-10)1-18-21(17,22)20-7;1-4-7(5-2)6-3/h2-4,6-7,10,16H,1H2,(H,17,22)(H2,11,12,13);4-6H2,1-3H3/p+1/t4?,6-,7?,10+,21+;/m0./s1
InchiKey	OXIPZMKSNMRTIV-FCRSUSRCSA-O
分子式 Formula	C16H28N6O5PS
分子量 Molecular Weight	447.47
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Rp-cAMPS TEA salt(CAS:71774-13-5):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Rp-cAMPS TEA salt is an activator of cAMP-dependent protein kinase (PKA).
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

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[2]Hess G. Synaptic plasticity of local connections in rat motor cortex. Acta Neurobiol Exp (Wars). 2004;64(2):271-6. Review. PubMed PMID: 15366258.

[3] Grzegorzewska M, Przybylo M, Litynska A, Hess G. Chemically-induced long-term potentiation in rat motor cortex involves activation of extracellular signal-regulated kinase cascade. Brain Res. 2004 Sep 24;1021(2):192-9. PubMed PMID: 15342267.

[4] Hayashi M, Kunii C, Takahata T, Ishikawa T. ATP-dependent regulation of SK4/IK1-like currents in rat submandibular acinar cells: possible role of cAMP-dependent protein kinase. Am J Physiol Cell Physiol. 2004 Mar;286(3):C635-46. Epub 2003 Nov 5. PubMed PMID: 14602578.

[5] Huang Y, Chan FL, Lau CW, Tsang SY, Chen ZY, He GW, Yao X. Roles of cyclic AMP and Ca2+-activated K+ channels in endothelium-independent relaxation by urocortin in the rat coronary artery. Cardiovasc Res. 2003 Mar;57(3):824-33. PubMed PMID: 12618244.

6: Haug T, Storm JF. Protein kinase A mediates the modulation of the slow Ca(2+)-dependent K(+) current, I(sAHP), by the neuropeptides CRF, VIP, and CGRP in hippocampal pyramidal neurons. J Neurophysiol. 2000 Apr;83(4):2071-9. PubMed PMID: 10758117.7: Lee AK, Tse A. Mechanism underlying corticotropin-releasing hormone (CRH) triggered cytosolic Ca2+ rise in identified rat corticotrophs. J Physiol. 1997 Oct 15;504 ( Pt 2):367-78. PubMed PMID: 9365911; PubMed Central PMCID: PMC1159917.8: Maggi CA, Giuliani S. Characterization of the apamin- and L-nitroarginine-resistant NANC inhibitory transmission to the circular muscle of guinea-pig colon. J Auton Pharmacol. 1996 Jun;16(3):131-45. PubMed PMID: 8884460.9: Haynes J Jr, Robinson J, Saunders L, Taylor AE, Strada SJ. Role of cAMP-dependent protein kinase in cAMP-mediated vasodilation. Am J Physiol. 1992 Feb;262(2 Pt 2):H511-6. PubMed PMID: 1311530.

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