1400742-17-7|QUPIC|1-Pentyl-1H-indole-3-carboxylic acid 8-quinolinyl ester|-范德生物科技公司

QUPIC

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names：
1-Pentyl-1H-indole-3-carboxylic acid 8-quinolinyl ester
CAS号：
1400742-17-7
MDL Number：
MF(分子式)： C23H22N2O2 MW(分子量)： 358.44
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	1-Pentyl-1H-indole-3-carboxylic acid 8-quinolinyl ester
英文别名	QUPIC; PB-22; 1-Pentyl-1H-indole-3-carboxylic acid 8-quinolinyl ester; PB 22; PB22
CAS号	1400742-17-7
Inchi	InChI=1S/C23H22N2O2/c1-2-3-6-15-25-16-19(18-11-4-5-12-20(18)25)23(26)27-21-13-7-9-17-10-8-14-24-22(17)21/h4-5,7-14,16H,2-3,6,15H2,1H3
InchiKey	ZAVGICCEAOUWFM-UHFFFAOYSA-N
分子式 Formula	C23H22N2O2
分子量 Molecular Weight	358.44
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	QUPIC(CAS:1400742-17-7):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	QUPIC is an analogue of JWH 018, the active component of marijuana. QUPIC is discontinued (DEA controlled substance).
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Münster-Müller S, Scheid N, Holdermann T, Schneiders S, Pütz M. Profiling of new psychoactive substances by using stable isotope ratio mass spectrometry: Study of the synthetic cannabinoid 5F-PB-22. Drug Test Anal. 2018 May 2[1]doi: 10.1002/dta.2407. [Epub ahead of print] PubMed PMID: 29782704.

[2]Tang ASY, Loh SWX, Koh HB, Tan S, Yap ATW, Zhang SH. Differentiation and identification of 5F-PB-22 and its isomers. Forensic Sci Int. 2017 Oct;279:53-59. doi: 10.1016/j.forsciint.2017.08.009. Epub 2017 Aug 12. PubMed PMID: 28846913.

[3] Drug Enforcement Administration, Department of Justice. Schedules of Controlled Substances: Placement of PB-22, 5F-PB-22, AB-FUBINACA and ADB-PINACA into Schedule I. Final rule. Fed Regist. 2016 Sep 6;81(172):61130-3. PubMed PMID: 27632803.

[4] Frinculescu A, Lyall CL, Ramsey J, Miserez B. Variation in commercial smoking mixtures containing third-generation synthetic cannabinoids. Drug Test Anal. 2017 Feb;9(2):327-333. doi: 10.1002/dta.1975. Epub 2016 May 10. PubMed PMID: 27161591.

[5] Drug Enforcement Administration, Department of Justice. Schedules of Controlled Substances: Extension of Temporary Placement of PB-22, 5F-PB-22, AB-FUBINACA and ADB-PINACA in Schedule I of the Controlled Substances Act. Final order. Fed Regist. 2016 Feb 5;81(24):6175-7. PubMed PMID: 26859904.

6: Gatch MB, Forster MJ. Δ9-Tetrahydrocannabinol-like effects of novel synthetic cannabinoids found on the gray market. Behav Pharmacol. 2015 Aug;26(5):460-8. doi: 10.1097/FBP.0000000000000150. PubMed PMID: 26061356; PubMed Central PMCID: PMC4497846.7: Gugelmann H, Gerona R, Li C, Tsutaoka B, Olson KR, Lung D. 'Crazy Monkey' poisons man and dog: Human and canine seizures due to PB-22, a novel synthetic cannabinoid. Clin Toxicol (Phila). 2014 Jul;52(6):635-8. doi: 10.3109/15563650.2014.925562. Epub 2014 Jun 6. PubMed PMID: 24905571.8: Takayama T, Suzuki M, Todoroki K, Inoue K, Min JZ, Kikura-Hanajiri R, Goda Y, Toyo'oka T. UPLC/ESI-MS/MS-based determination of metabolism of several new illicit drugs, ADB-FUBINACA, AB-FUBINACA, AB-PINACA, QUPIC, 5F-QUPIC and α-PVT, by human liver microsome. Biomed Chromatogr. 2014 Jun;28(6):831-8. doi: 10.1002/bmc.3155. PubMed PMID: 24861751.9: Drug Enforcement Administration, Department of Justice. Schedules of controlled substances: temporary placement of four synthetic cannabinoids into Schedule I. Final order. Fed Regist. 2014 Feb 10;79(27):7577-82. PubMed PMID: 24605391.

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