121011-80-1|Pseudopterosin E|alpha-L-Galactopyranoside, (1S,3R,7S,9aR)-2,3,7,8,9,9a-hexahydro-6-hydroxy-1,4,7-trimethyl-3-(2-methyl-1-propen-1-yl)-1H-phenalen-5-yl 6-deoxy-|-范德生物科技公司

Pseudopterosin E

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names：
alpha-L-Galactopyranoside, (1S,3R,7S,9aR)-2,3,7,8,9,9a-hexahydro-6-hydroxy-1,4,7-trimethyl-3-(2-methyl-1-propen-1-yl)-1H-phenalen-5-yl 6-deoxy-
CAS号：
121011-80-1
MDL Number：
MF(分子式)： C26H38O6 MW(分子量)： 446.58
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	alpha-L-Galactopyranoside, (1S,3R,7S,9aR)-2,3,7,8,9,9a-hexahydro-6-hydroxy-1,4,7-trimethyl-3-(2-methyl-1-propen-1-yl)-1H-phenalen-5-yl 6-deoxy-
英文别名	Pseudopterosin E
CAS号	121011-80-1
Inchi	InChI=1S/C26H38O6/c1-11(2)9-16-10-13(4)17-8-7-12(3)18-20(17)19(16)14(5)25(22(18)28)32-26-24(30)23(29)21(27)15(6)31-26/h9,12-13,15-17,21,23-24,26-30H,7-8,10H2,1-6H3/t12-,13-,15-,16-,17+,21+,23+,24-,26-/m0/s1
InchiKey	LIAAPIYLHKRUNZ-BRPLUSLASA-N
分子式 Formula	C26H38O6
分子量 Molecular Weight	446.58
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Pseudopterosin E(CAS:121011-80-1):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Pseudopterosin E has an effect against Mycobacterium tuberculosis and other pathogens.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]McCulloch MW, Haltli B, Marchbank DH, Kerr RG. Evaluation of pseudopteroxazole and pseudopterosin derivatives against Mycobacterium tuberculosis and other pathogens. Mar Drugs. 2012 Aug;10(8):1711-28. Epub 2012 Aug 15. PubMed PMID: 23015770; PubMed Central PMCID: PMC3447335.

[2]Newton CG, Sherburn MS. Total synthesis of the pseudopterosin aglycones. Nat Prod Rep. 2015 Jun;32(6):865-76. doi: 10.1039/c5np00008d. Review. PubMed PMID: 25882677.

[3] Newton CG, Drew SL, Lawrence AL, Willis AC, Paddon-Row MN, Sherburn MS. Pseudopterosin synthesis from a chiral cross-conjugated hydrocarbon through a series of cycloadditions. Nat Chem. 2015 Jan;7(1):82-6. doi: 10.1038/nchem.2112. Epub 2014 Nov 17. PubMed PMID: 25515894.

[4] Flachsmann F, Schellhaas K, Moya CE, Jacobs RS, Fenical W. Synthetic pseudopterosin analogues: A novel class of antiinflammatory drug candidates. Bioorg Med Chem. 2010 Dec 1;18(23):8324-33. doi: 10.1016/j.bmc.2010.09.067. Epub 2010 Oct 7. PubMed PMID: 21041093.

[5] Lazerwith SE, Johnson TW, Corey EJ. Syntheses and stereochemical revision of pseudopterosin G-J aglycon and helioporin E. Org Lett. 2000 Jul 27;2(15):2389-92. PubMed PMID: 10930291.

6: Xiong M, Guo Z, Han B, Chen M. Combating multidrug resistance in bacterial infection by targeting functional proteome with natural products. Nat Prod Res. 2015;29(17):1624-9. doi: 10.1080/14786419.2014.991926. Epub 2014 Dec 18. PubMed PMID: 25518752.7: Puyana M, Narvaez G, Paz A, Osorno O, Duque C. Pseudopterosin content variability of the purple sea whip Pseudopterogorgia elisabethae at the islands of San Andres and Providencia (SW Caribbean). J Chem Ecol. 2004 Jun;30(6):1183-201. PubMed PMID: 15303322.8: Day DR, Jabaiah S, Jacobs RS, Little RD. Cyclodextrin formulation of the marine natural product pseudopterosin A uncovers optimal pharmacodynamics in proliferation studies of human umbilical vein endothelial cells. Mar Drugs. 2013 Aug 26;11(9):3258-71. doi: 10.3390/md11093258. PubMed PMID: 24065164; PubMed Central PMCID: PMC3806459.9: Caplan SL, Zheng B, Dawson-Scully K, White CA, West LM. Pseudopterosin A: Protection of Synaptic Function and Potential as a Neuromodulatory Agent. Mar Drugs. 2016 Mar 10;14(3). pii: E55. doi: 10.3390/md14030055. PubMed PMID: 26978375; PubMed Central PMCID: PMC4820309.10: Mayer AM, Jacobson PB, Fenical W, Jacobs RS, Glaser KB. Pharmacological characterization of the pseudopterosins: novel anti-inflammatory natural products isolated from the Caribbean soft coral, Pseudopterogorgia elisabethae. Life Sci. 1998;62(26):PL401-7. PubMed PMID: 9651113.1

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