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684283-16-7
  • names:

    cis-PPDA, GluN2C/GluN2D NMDA antagonist

  • CAS号:

    684283-16-7

    MDL Number:
  • MF(分子式): C21H18N2O5 MW(分子量): 378.384
  • EINECS: Reaxys Number:
  • Pubchem ID:20811874 Brand:BIOFOUNT
cis-PPDA
cis-PPDA(684283-16-7)是一种强效 GluN2C/GluN2D(以前称为 NR2C / NR2D)NMDA 受体拮抗剂。
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中文别名 cis-PPDA(684283-16-7);(2S*,3R*)-1-(Phenanthren-2-carbonyl)piperazine-2,3-dicarboxylic acid;GluN2C NMDA拮抗剂;GluN2D NMDA 拮抗剂
英文别名 cis-PPDA, GluN2C/GluN2D NMDA antagonist(684283-16-7);PPDA
CAS号 684283-16-7
SMILES O=C([C@H]1N(C(C2=CC=C3C4=CC=CC=C4C=CC3=C2)=O)CCN[C@H]1C(O)=O)O
Inchi InChI=1S/C21H18N2O5/c24-19(23-10-9-22-17(20(25)26)18(23)21(27)28)14-7-8-16-13(11-14)6-5-12-3-1-2-4-15(12)16/h1-8,11,17-18,22H,9-10H2,(H,25,26)(H,27,28)/t17-,18+/m1/s1
InchiKey IWWXIZOMXGOTPP-MSOLQXFVSA-N
分子式 Formula C21H18N2O5
分子量 Molecular Weight 378.384
闪点 FP No data available
熔点 Melting point no data available
沸点 Boiling point no data available
Polarizability极化度 No data available
密度 Density No data available
蒸汽压 Vapor Pressure No data available
溶解度Solubility
性状 Solid powder
储藏条件 Storage conditions Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

cis-PPDA(684283-16-7)功能研究:
cis-PPDA(684283-16-7)是一种强效 GluN2C/GluN2D(以前称为 NR2C / NR2D)NMDA 受体拮抗剂。(重组大鼠受体的 Ki 值为 0.096 (NR2C)、0.125 (NR2D)、0.55 (NR2A) 和 0.31 μM (NR2B))。

cis-PPDA(684283-16-7)使用注意事项:
1.实验前需戴好防护眼镜,穿戴防护服和口罩,佩戴手套,避免与皮肤接触。
2.实验过程中如遇到有毒或者刺激性物质及有害物质产生,必要时实验操作需要手套箱内完成以免对实验人员造成伤害。
3.取样品的移液枪头需及时更换,必要时为避免交叉污染尽可能选择滤芯吸头。
4.称量药品时选用称量纸,并无风处取药和称量以免扬撒,试剂的容器使用前务必确保干净,并消毒。
5.取药品时尽量采用多个药勺分别使用,使用后清洗干净。
6.实验后产生的废弃物需分类存储,并交于专业生物废气物处理公司处理,以免造成环境污染。
大规格定制:定制产品请将信息发送至sales@bio-fount.com。
Experimental considerations:
1. Wear protective glasses, protective clothing and masks, gloves, and avoid contact with the skin during the experiment.
2. The waste generated after the experiment needs to be stored separately, and handed over to a professional biological waste gas treatment company to avoid environmental pollution.
产品说明 PPDA(CAS:684283-16-7):仅限应用于工业或者科学研究过程中非医疗目的,不应用于人类或动物的临床诊断以及治过程疗,该产品非药用,非食用。
IntroductionPPDA is a subtype-selective NMDA receptor antagonist that preferentially binds to NR2C/NR2D-containing receptors.
Application1
Application2
Application3
[1]Kishimoto S, Matsumoto T, Maruhashi T, Iwamoto Y, Kajikawa M, Oda N, Matsui S, Hashimoto H, Hidaka T, Kihara Y, Chayama K, Goto C, Aibara Y, Yusoff FBM, Nakashima A, Noma K, Higashi Y. Reactive hyperemia-peripheral arterial tonometry is useful for assessment of not only endothelial function but also stenosis of the digital artery. Int J Cardiol. 2018 Jun 1;260:178-183. doi: 10.1016/j.ijcard.2017.10.069. PubMed PMID: 29622435.
[2]Targhoo A, Amiri A, Baghayeri M. Magnetic nanoparticles coated with poly(p-phenylenediamine-co-thiophene) as a sorbent for preconcentration of organophosphorus pesticides. Mikrochim Acta. 2017 Dec 5;185(1):15. doi: 10.1007/s00604-017-2560-1. PubMed PMID: 29594381.
[3] Zhang X, Zhan Z, Liang X, Chen C, Liu X, Jia Y, Hu M. Lanthanide-MOFs constructed from mixed dicarboxylate ligands as selective multi-responsive luminescent sensors. Dalton Trans. 2018 Mar 6;47(10):3272-3282. doi: 10.1039/c7dt02966g. PubMed PMID: 29431809.
[4] Byrne AW, Graham J, Brown C, Donaghy A, Guelbenzu-Gonzalo M, McNair J, Skuce RA, Allen A, McDowell SW. Modelling the variation in skin-test tuberculin reactions, post-mortem lesion counts and case pathology in tuberculosis-exposed cattle: Effects of animal characteristics, histories and co-infection. Transbound Emerg Dis. 2018 Jan 23. doi: 10.1111/tbed.12814. [Epub ahead of print] PubMed PMID: 29363285.
[5] Parsons SDC, Morar-Leather D, Buss P, Hofmeyr J, McFadyen R, Rutten VPMG, van Helden PD, Miller MA, Michel AL. The Kinetics of the Humoral and Interferon-Gamma Immune Responses to Experimental Mycobacterium bovis Infection in the White Rhinoceros (Ceratotherium simum). Front Immunol. 2017 Dec 22;8:1831. doi: 10.3389/fimmu.2017.01831. eCollection 2017. PubMed PMID: 29312328; PubMed Central PMCID: PMC5743672.
6: Joharian M, Abedi S, Morsali A. Sonochemical synthesis and structural characterization of a new nanostructured Co(II) supramolecular coordination polymer with Lewis base sites as a new catalyst for Knoevenagel condensation. Ultrason Sonochem. 2017 Nov;39:897-907. doi: 10.1016/j.ultsonch.2017.06.009. Epub 2017 Jun 15. PubMed PMID: 28733021.7: Lu W, Yang H, Li X, Wang C, Zhan X, Qi D, Bian Y, Jiang J. Chiral Discrimination of Diamines by a Binaphthalene-Bridged Porphyrin Dimer. Inorg Chem. 2017 Jul 17;56(14):8223-8231. doi: 10.1021/acs.inorgchem.7b00920. Epub 2017 Jun 24. PubMed PMID: 28648063.8: Mikics E, Toth M, Biro L, Bruzsik B, Nagy B, Haller J. The role of GluN2B-containing NMDA receptors in short- and long-term fear recall. Physiol Behav. 2017 Aug 1;177:44-48. doi: 10.1016/j.physbeh.2017.04.005. Epub 2017 Apr 8. PubMed PMID: 28400283.9: Williams JC, Nguyen BN, McCorkle L, Scheiman D, Griffin JS, Steiner SA 3rd, Meador MA. Highly Porous, Rigid-Rod Polyamide Aerogels with Superior Mechanical Properties and Unusually High Thermal Conductivity. ACS Appl Mater Interfaces. 2017 Jan 18;9(2):1801-1809. doi: 10.1021/acsami.6b13100. Epub 2017 Jan 6. PubMed PMID: 28060486.10: Xu Z, Xue P, Gao YE, Liu S, Shi X, Hou M, Kang Y. pH-responsive polymeric micelles based on poly(ethyleneglycol)-b-poly(2-(diisopropylamino) ethyl methacrylate) block copolymer for enhanced intracellular release of anticancer drugs. J Colloid Interface Sci. 2017 Mar 15;490:511-519. doi: 10.1016/j.jcis.2016.11.091. Epub 2016 Nov 27. PubMed PMID: 27918989.1
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