70384-91-7|Lortalamine|(4aS,10S,10aS)-8-chloro-2-methyl-1,2,3,4,10,10a-hexahydro-4a,10-(epiminoethano)chromeno[3,2-c]pyridin-12-one|-范德生物科技公司

Lortalamine

NMR下载 COA and HPLC MSDS下载
names：
(4aS,10S,10aS)-8-chloro-2-methyl-1,2,3,4,10,10a-hexahydro-4a,10-(epiminoethano)chromeno[3,2-c]pyridin-12-one
CAS号：
70384-91-7
MDL Number：
MF(分子式)： C15H17ClN2O2 MW(分子量)： 292.76
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

货品编码	规格	纯度	价格 (¥)	现价(¥)	特价(¥)	库存描述	数量	总计 (¥)

大包装询价提供各种包装，敬请垂询
收藏商品商品点评加入购物车立即购买

快速询价

收起

你想询价的产品

*产品名称：

CAS号：

产品编号：

需求描述：

请准确填写您的联系方式，以便为您提供最好的服务。

*公司名称：

*电子邮箱：

联系人：

*电话：

*验证码：

询价

中文别名	Lortalamine
英文别名	Lortalamine; LM-1404; LM 1404; LM1404;
CAS号	70384-91-7
Inchi	InChI=1S/C15H17ClN2O2/c1-18-5-4-15-12(8-18)10(7-14(19)17-15)11-6-9(16)2-3-13(11)20-15/h2-3,6,10,12H,4-5,7-8H2,1H3,(H,17,19)/t10-,12-,15+/m1/s1
InchiKey	MJRPHRMGEKCADU-HCKVZZMMSA-N
分子式 Formula	C15H17ClN2O2
分子量 Molecular Weight	292.76
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Lortalamine(CAS:70384-91-7):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Lortalamine is an antidepressant which was synthesized in the early 1980s. It acts as a potent and highly selective norepinephrine reuptake inhibitor.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Depin JC, Betbeder-Matibet A, Bonhomme Y, Muller AJ, Berthelon JJ. Pharmacology of lortalamine, a new potent non-tricyclic antidepressant. Arzneimittelforschung. 1985;35(11):1655-62. PubMed PMID: 4091869.

[2]Mally C, Thiebault JJ. Ocular toxicity in beagle dogs with lortalamine, a non tricyclic antidepressant compound. Drug Chem Toxicol. 1990;13(4):309-23. PubMed PMID: 2279460.

[3] Ding YS, Lin KS, Logan J, Benveniste H, Carter P. Comparative evaluation of positron emission tomography radiotracers for imaging the norepinephrine transporter: (S,S) and (R,R) enantiomers of reboxetine analogs ([11C]methylreboxetine, 3-Cl-[11C]methylreboxetine and [18F]fluororeboxetine), (R)-[11C]nisoxetine, [11C]oxaprotiline and [11C]lortalamine. J Neurochem. 2005 Jul;94(2):337-51. PubMed PMID: 15998285.

[4] Elsom LF, Biggs SR, Chasseaud LF, Hawkins DR, Pulsford J, Darragh A. Metabolism of the anti-depressant lortalamine. Eur J Drug Metab Pharmacokinet. 1985 Jul-Sep;10(3):209-15. PubMed PMID: 4085522.

[5] Lin KS, Ding YS. Synthesis and C-11 labeling of three potent norepinephrine transporter selective ligands ((R)-nisoxetine, lortalamine, and oxaprotiline) for comparative PET studies in baboons. Bioorg Med Chem. 2005 Aug 1;13(15):4658-66. PubMed PMID: 15914010.

6: Ding YS, Lin KS, Logan J. PET imaging of norepinephrine transporters. Curr Pharm Des. 2006;12(30):3831-45. Review. PubMed PMID: 17073682.7: Belleville M, Grand M, Briet P. Plasma levels, elimination and metabolic fate of 4a-amino-8-chloro-2-methyl-1,2,3,4,4a,10a-hexahydro-10H-benzopyrano[3,2-c]pyridin -10-ylacetic acid lactam, a new antidepressive agent, in rats and dogs. Drug Metab Dispos. 1981 May-Jun;9(3):233-9. PubMed PMID: 6113932.

对不起，暂无产品评价！

MSDS

SDS 1.0 中文

展开

SDS 1.0 英文

展开