104340-86-5|Leminoprazole|2-(((1H-benzo[d]imidazol-2-yl)sulfinyl)methyl)-N-isobutyl-N-methylaniline|-范德生物科技公司

Leminoprazole

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names：
2-(((1H-benzo[d]imidazol-2-yl)sulfinyl)methyl)-N-isobutyl-N-methylaniline
CAS号：
104340-86-5
MDL Number：
MF(分子式)： C19H23N3OS MW(分子量)： 341.473
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	Leminoprazole
英文别名	Leminoprazole
CAS号	104340-86-5
Inchi	InChI=1S/C19H23N3OS/c1-14(2)12-22(3)18-11-7-4-8-15(18)13-24(23)19-20-16-9-5-6-10-17(16)21-19/h4-11,14H,12-13H2,1-3H3,(H,20,21)
InchiKey	PSIREIZGKQBEEO-UHFFFAOYSA-N
分子式 Formula	C19H23N3OS
分子量 Molecular Weight	341.473
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Leminoprazole(CAS:104340-86-5):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Leminoprazole, an acid pump inhibitor, has a mucosal protective effect against various experimental gastric lesion.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Takahashi S, Okabe S. Mechanism by which orally administered leminoprazole stimulates mucus synthesis in rats. Pharmacology. 1998 Jul;57(1):47-56. PubMed PMID: 9670212.

[2]Takahashi S, Okabe S. The cytoprotective effect of leminoprazole on indomethacin-induced damage to rabbit gastric mucosal cells. J Pharmacol Exp Ther. 1996 Nov;279(2):975-82. PubMed PMID: 8930207.

[3] Okabe S, Amagase K, Fujita H, Iwata K, Satake N, Shibata S. Vasoinhibitory effect of leminoprazole, a H+,K(+)-ATPase inhibitor, on rat aortic rings. Gen Pharmacol. 1996 Jan;27(1):117-21. PubMed PMID: 8742507.

[4] Okabe S, Shimosako K, Harada H. Antisecretory effect of leminoprazole on histamine-stimulated gastric acid secretion in dogs: potent local effect. Jpn J Pharmacol. 1995 Oct;69(2):91-100. PubMed PMID: 8569059.

[5] Takahashi S, Tsukahara T, Okabe S. Effects of acid-degraded products of leminoprazole on acid secretion, mucus secretion and synthesis, and indomethacin-induced damage in cell culture. J Physiol Pharmacol. 1998 Mar;49(1):99-110. PubMed PMID: 9594414.

6: Matsukura H, Masuda M, Uchida A, Kamishiro T. [Effect of a new antiulcer drug, leminoprazole, on the gastric mucosal H+,K(+)-ATPase activity in rats]. Nihon Yakurigaku Zasshi. 1994 Aug;104(2):91-100. Japanese. PubMed PMID: 7927073.7: Tsukimi Y, Nozue C, Okabe S. Effects of leminoprazole, omeprazole and sucralfate on indomethacin-induced delayed healing of kissing gastric ulcers in rats. J Gastroenterol Hepatol. 1996 Apr;11(4):335-40. PubMed PMID: 8713699.8: Takahashi S, Yamazaki T, Okabe S. Leminoprazole protects cultured gastric mucosal cells against damage caused by ethanol, indometacin and taurocholate. Pharmacology. 1997 Mar;54(3):118-26. PubMed PMID: 9127434.9: Takahashi S, Nakamura E, Okabe S. Stimulatory effect of leminoprazole on secretion and synthesis of mucus by rabbit gastric mucosal cells. J Pharmacol Exp Ther. 1995 Dec;275(3):1396-401. PubMed PMID: 8531108.10: Saito E, Matsuo Y. Inhibitory effect of leminoprazole on acid secretion in parietal cells isolated from guinea pig gastric mucosa. Jpn J Pharmacol. 1995 May;68(1):19-23. PubMed PMID: 7494378.

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