77167-93-2|L 640035|3-(hydroxymethyl)dibenzo[b,f]thiepine 5,5-dioxide|-范德生物科技公司

L 640035

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names：
3-(hydroxymethyl)dibenzo[b,f]thiepine 5,5-dioxide
CAS号：
77167-93-2
MDL Number：
MF(分子式)： C15H12O3S MW(分子量)： 272.31
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	L 640035
英文别名	L 640035; L-640035; L640035; L-640,035; L 640,035; L640,035;
CAS号	77167-93-2
Inchi	InChI=1S/C15H12O3S/c16-10-11-5-6-13-8-7-12-3-1-2-4-14(12)19(17,18)15(13)9-11/h1-9,16H,10H2
InchiKey	NYFDVYBQHBRTNS-UHFFFAOYSA-N
分子式 Formula	C15H12O3S
分子量 Molecular Weight	272.31
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	L 640035(CAS:77167-93-2):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	L 640035 inhibits human platelet aggregation induced by arachidonic acid, collagen & prostaglandin endoperoxide analog of U44069.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
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备注

[1]Swayne GT, Maguire J, Dolan J, Raval P, Dane G, Greener M, Owen DA. Evidence for homogeneity of thromboxane A2 receptor using structurally different antagonists. Eur J Pharmacol. 1988 Aug 2;152(3):311-9. PubMed PMID: 2975605.

[2]Khirabadi BS, Foegh ML, Goldstein HA, Ramwell PW. The effect of prednisolone, thromboxane, and platelet-activating factor receptor antagonists on lymphocyte and platelet migration in experimental cardiac transplantation. Transplantation. 1987 May;43(5):626-30. PubMed PMID: 3033853.

[3] Ganey PE, Roth RA. Thromboxane does not mediate pulmonary vascular response to monocrotaline pyrrole. Am J Physiol. 1987 Apr;252(4 Pt 2):H743-8. PubMed PMID: 2952022.

[4] Melki TS, Foegh ML, Ramwell PW. Implication of thromboxane in frusemide diuresis in rats. Clin Sci (Lond). 1986 Dec;71(6):647-50. PubMed PMID: 3791866.

[5] Foegh ML, Khirabadi BS, Ramwell PW. Platelet deposition in rat heart allografts and the effect of a thromboxane receptor antagonist. J Heart Transplant. 1986 Jul-Aug;5(4):338-9. PubMed PMID: 2957473.

6: Foegh ML, Khirabadi B, Ramwell PW. Prolongation of experimental cardiac allograft survival with thromboxane-related drugs. Transplantation. 1985 Aug;40(2):124-5. PubMed PMID: 3161224.7: Chan CC, Ford-Hutchinson A. Potentiation of the inhibitory effect of a thromboxane A2 antagonist (L-640,035) on arterial thrombosis formation in rabbit by the angiotensin converting enzyme inhibitor enalapril. Eur J Pharmacol. 1985 Apr 16;110(3):323-8. PubMed PMID: 2988983.8: Slobodzian DK, Hsieh JY, Bayne WF. High-performance liquid chromatographic determination of 3-hydroxymethyl-dibenzo[b,f]thiepin 5,5-dioxide and its acid metabolite in human plasma and urine. J Chromatogr. 1985 Feb 27;338(1):253-8. PubMed PMID: 4019653.9: Foegh ML, Alijani MR, Helfrich GB, Khirabadi BS, Goldman MH, Lower RR, Ramwell PW. Thromboxane and leukotrienes in clinical and experimental transplant rejection. Adv Prostaglandin Thromboxane Leukot Res. 1985;1

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