5034-76-4|Indoxole|2,3-bis(4-methoxyphenyl)-1H-indole|-范德生物科技公司

Indoxole

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names：
2,3-bis(4-methoxyphenyl)-1H-indole
CAS号：
5034-76-4
MDL Number：
MF(分子式)： C22H19NO2 MW(分子量)： 329.399
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	Indoxole
英文别名	Indoxole; U 22020; U-22020; U22020
CAS号	5034-76-4
Inchi	InChI=1S/C22H19NO2/c1-24-17-11-7-15(8-12-17)21-19-5-3-4-6-20(19)23-22(21)16-9-13-18(25-2)14-10-16/h3-14,23H,1-2H3
InchiKey	SRETXDDCKMOQNE-UHFFFAOYSA-N
分子式 Formula	C22H19NO2
分子量 Molecular Weight	329.399
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Indoxole(CAS:5034-76-4):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Indoxole is an anti-inflammatory drug effective against carrageenin-induced edema in intact and adrenalectomized rats and in mice and gerbils.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Lednicer D. Tracing the origins of COX-2 inhibitors' structures. Curr Med Chem. 2002 Aug;9(15):1457-6[1]Review. PubMed PMID: 12173976.

[2]Collier HO, James GW, Piper PJ. Antagonism by fenamates and like-acting drugs of bronchoconstriction induced by bradykinin or antigen in the guinea-pig. Br J Pharmacol. 1968 Sep;34(1):76-87. PubMed PMID: 5676040; PubMed Central PMCID: PMC1703405.

[3] Spinelli HM, Krohn DL. Inhibition of prostaglandin-induced iritis. Topical indoxole vs indomethacin therapy. Arch Ophthalmol. 1980 Jun;98(6):1106-9. PubMed PMID: 7387517.

[4] Smolin G, Okumoto M, Hall JM, Friedlaender M. The effect of indoxole on the corneal immunologic response. Ann Ophthalmol. 1979 Feb;11(2):227-232. PubMed PMID: 86318.

[5] Podos SM, Becker B. Comparison of ocular prostaglandin synthesis inhibitors. Invest Ophthalmol. 1976 Oct;15(10):841-4. PubMed PMID: 977253.

6: Schaeffer HE, Krohn DL. Liposomes in topical drug delivery. Invest Ophthalmol Vis Sci. 1982 Feb;22(2):220-7. PubMed PMID: 7056633.7: Glenn EM, Bowman BJ, Kooyers W, Koslowske T, Myers ML. The pharmacology of 2,3-bis-(p-methoxyphenyl)-indole (indoxole). J Pharmacol Exp Ther. 1967 Jan;155(1):157-66. PubMed PMID: 6017336.8: Whitehouse MW. Evaluation of potential antirheumatic drugs in vitro using lymphocytes and epithelial cells. The selective action of indoxole, methyl glyoxal and chloroquine. J Pharm Pharmacol. 1967 Sep;19(9):590-5. PubMed PMID: 4383451.9: Wagner JG, Gerard ES, Kaiser DG. The effect of the dosage form on serum levels of indoxole. Clin Pharmacol Ther. 1966 Sep-Oct;7(5):610-9. PubMed PMID: 5957166.10: Kaiser DG, Bowman BJ, Forist AA. Fluorometric determination of indoxole [2,3-bis-(p-methoxyphenyl)-indole] in biological specimens. Anal Chem. 1966 Jul;38(8):977-80. PubMed PMID: 5941080.1

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