110325-85-4|Gdpflrfamide|(S)-4-((S)-2-(((S)-1-(((S)-1-(((S)-1-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamoyl)pyrrolidin-1-yl)-3-(2-aminoacetamido)-4-oxobutanoic acid|-范德生物科技公司

Gdpflrfamide

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names：
(S)-4-((S)-2-(((S)-1-(((S)-1-(((S)-1-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamoyl)pyrrolidin-1-yl)-3-(2-aminoacetamido)-4-oxobutanoic acid
CAS号：
110325-85-4
MDL Number：
MF(分子式)： C41H59N11O9 MW(分子量)： 849.99
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Gdpflrfamide
英文别名	Gdpflrfamide; Gly-asp-pro-phe-leu-arg-phe-amide;
CAS号	110325-85-4
Inchi	InChI=1S/C41H59N11O9/c1-24(2)19-29(37(58)48-27(15-9-17-46-41(44)45)36(57)49-28(35(43)56)20-25-11-5-3-6-12-25)50-38(59)30(21-26-13-7-4-8-14-26)51-39(60)32-16-10-18-52(32)40(61)31(22-34(54)55)47-33(53)23-42/h3-8,11-14,24,27-32H,9-10,15-23,42H2,1-2H3,(H2,43,56)(H,47,53)(H,48,58)(H,49,57)(H,50,59)(H,51,60)(H,54,55)(H4,44,45,46)/t27-,28-,29-,30-,31-,32-/m0/s1
InchiKey	CZDLNUYGHZETAQ-JNRWAQIZSA-N
分子式 Formula	C41H59N11O9
分子量 Molecular Weight	849.99
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Gdpflrfamide(CAS:110325-85-4):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Gdpflrfamide is a neuropeptide found in the snail Lymnaea stagnalis.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Skingsley DR, Bright K, Santama N, van Minnen J, Brierley MJ, Burke JF, Benjamin PR. A molecularly defined cardiorespiratory interneuron expressing SDPFLRFamide/GDPFLRFamide in the snail Lymnaea: monosynaptic connections and pharmacology. J Neurophysiol. 1993 Mar;69(3):915-27. PubMed PMID: 8096540.

[2]Saunders SE, Bright K, Kellett E, Benjamin PR, Burke JF. Neuropeptides Gly-Asp-Pro-Phe-Leu-Arg-Phe-amide (GDPFLRFamide) and Ser-Asp-Pro-Phe-Leu-Arg-Phe-amide (SDPFLRFamide) are encoded by an exon 3' to Phe-Met-Arg-Phe-NH2 (FMRFamide) in the snail Lymnaea stagnalis. J Neurosci. 1991 Mar;11(3):740-5. PubMed PMID: 2002360.

[3] Ebberink RH, Price DA, van Loenhout H, Doble KE, Riehm JP, Geraerts WP, Greenberg MJ. The brain of Lymnaea contains a family of FMRFamide-like peptides. Peptides. 1987 May-Jun;8(3):515-22. PubMed PMID: 3658814.

[4] Nesic OB, Magoski NS, McKenney KK, Syed NI, Lukowiak K, Bulloch AG. Glutamate as a putative neurotransmitter in the mollusc, Lymnaea stagnalis. Neuroscience. 1996 Dec;75(4):1255-69. PubMed PMID: 8938758.

[5] Richmond JE, Funte LR, Smith WL, Price DA, Haydon PG. Activation of a peptidergic synapse locally modulates postsynaptic calcium influx. J Exp Biol. 1991 Nov;16[5]257-71. PubMed PMID: 1684615.

6: Madrid KP, Price DA, Greenberg MJ, Khan HR, Saleuddin AS. FMRFamide-related peptides from the kidney of the snail, Helisoma trivolvis. Peptides. 1994 Jan;15(1):31-6. PubMed PMID: 7912428.7: Salzet M, Bulet P, Wattez C, Malecha J. FMRFamide-related peptides in the sex segmental ganglia of the Pharyngobdellid leech Erpobdella octoculata. Identification and involvement in the control of hydric balance. Eur J Biochem. 1994 Apr 1;221(1):269-75. PubMed PMID: 8168516.8: De Lange RP, Joosse J, Van Minnen J. Multi-messenger innervation of the male sexual system of Lymnaea stagnalis. J Comp Neurol. 1998 Jan 26;390(4):564-77. PubMed PMID: 9450536.9: Bright K, Kellett E, Saunders SE, Brierley M, Burke JF, Benjamin PR. Mutually exclusive expression of alternatively spliced FMRFamide transcripts in identified neuronal systems of the snail Lymnaea. J Neurosci. 1993 Jun;13(6):2719-29. PubMed PMID: 8501534.10: Buckett KJ, Dockray GJ, Osborne NN, Benjamin PR. Pharmacology of the myogenic heart of the pond snail Lymnaea stagnalis. J Neurophysiol. 1990 Jun;63(6):1413-25. PubMed PMID: 1694238.1

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