38957-41-4|Emorfazone|3(2H)-Pyridazinone, 4-ethoxy-2-methyl-5-morpholino-|-范德生物科技公司

Emorfazone

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names：
3(2H)-Pyridazinone, 4-ethoxy-2-methyl-5-morpholino-
CAS号：
38957-41-4
MDL Number：
MF(分子式)： C11H17N3O3 MW(分子量)： 239.275
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

货品编码	规格	纯度	价格 (¥)	现价(¥)	特价(¥)	库存描述	数量	总计 (¥)
FMK14934-100mg	100mg	>98%	¥ 0.00	¥ 0.00		Get quote	- +	¥ 0.00

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中文别名	Emorfazone
英文别名	Emorfazone; M 73101; M73101
CAS号	38957-41-4
Inchi	InChI=1S/C11H17N3O3/c1-3-17-10-9(8-12-13(2)11(10)15)14-4-6-16-7-5-14/h8H,3-7H2,1-2H3
InchiKey	URJQOOISAKEBKW-UHFFFAOYSA-N
分子式 Formula	C11H17N3O3
分子量 Molecular Weight	239.275
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Emorfazone(CAS:38957-41-4):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Emorfazone has an anti-nociceptive effect.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Piaz VD, Vergelli C, Giovannoni MP, Scheideler MA, Petrone G, Zaratin P. 4-Amino-3(2H)-pyridazinones bearing arylpiperazinylalkyl groups and related compounds: synthesis and antinociceptive activity. Farmaco. 2003 Nov;58(11):1063-7[1]PubMed PMID: 14572856.

[2]Takaya M, Sato M. [Studies on pyridazinone derivatives. XVI. Analgesic-antiinflammatory activities of 3(2H)-pyridazinone derivatives]. Yakugaku Zasshi. 1994 Feb;114(2):94-110. Japanese. PubMed PMID: 8169774.

[3] Khan AA, Malik S, Zuberi NI. Double blind study on emorfazone and ibuprofen in dental pain and inflammation. J Pak Med Assoc. 1992 Jan;42(1):17-8. PubMed PMID: 1545477.

[4] Hiranuma T, Kato S, Hachisu M. Analgesic action of amfenac Na, a non-steroidal anti-inflammatory agent. J Pharmacobiodyn. 1988 Sep;11(9):612-9. PubMed PMID: 3265150.

[5] Maki Y, Shimada K, Sako M, Kitade Y, Hirota K. Photochemical oxidation of 4-ethoxy-2-methyl-5-morpholino-3(2H)-pyridazinone (Emorfazone) by pyrimido[5,4-g]pteridine 5-oxide. An attempt to apply a functional chemical model for biological oxidations to drug-metabolism studies. Chem Pharm Bull (Tokyo). 1988 May;36(5):1714-20. PubMed PMID: 3203412.

6: Yonehara N, Shibutani T, Inoki R. Contribution of substance P to heat-induced edema in rat paw. J Pharmacol Exp Ther. 1987 Sep;242(3):1071-6. PubMed PMID: 2443642.7: Hatano M, Yamada T, Yoshida A, Miyata K, Okusawa S, Hoya I, Miura K, Ishihara M. [Studies on isolated rat hepatocytes (6)]. Josai Shika Daigaku Kiyo. 1984;13(1):156-64. Japanese. PubMed PMID: 6596968.8: Hayashi T, Amino M, Ikoma Y. Changes of metabolism and substrate-binding spectrum of emorfazone between immature and mature guinea-pigs. Xenobiotica. 1983 Aug;13(8):461-6. PubMed PMID: 6649679.9: Hayashi T. Metabolism of 4-ethoxy-2-methyl-5-morpholino-3(2H)-pyridazinone (emorfazone). V. Effect of inducer pretreatment on oxygenation of the morpholino moiety in guinea pigs. Chem Pharm Bull (Tokyo). 1982 Oct;30(10):3748-56. PubMed PMID: 7160018.10: Sato M. Effects of emorfazone on the nociceptive response induced by bradykinin in rats and dogs. Arch Int Pharmacodyn Ther. 1982 Jun;257(2):200-12. PubMed PMID: 6956248.1

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