232617-15-1|D-Ribose-L-cysteine|(4R)-2-((1R,2R,3R)-1,2,3,4-tetrahydroxybutyl)thiazolidine-4-carboxylic acid|-范德生物科技公司

D-Ribose-L-cysteine

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names：
(4R)-2-((1R,2R,3R)-1,2,3,4-tetrahydroxybutyl)thiazolidine-4-carboxylic acid
CAS号：
232617-15-1
MDL Number：
MF(分子式)： C8H15NO6S MW(分子量)： 253.26
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	D-Ribose-L-cysteine
英文别名	D-Ribose-L-cysteine; Ribcys; J424.013H; Riboceine; D Ribose L cysteine; DRiboseLcysteine;
CAS号	232617-15-1
Inchi	InChI=1S/C8H15NO6S/c10-1-4(11)5(12)6(13)7-9-3(2-16-7)8(14)15/h3-7,9-13H,1-2H2,(H,14,15)/t3-,4+,5+,6+,7?/m0/s1
InchiKey	AGZXTDUDXXPCMJ-HZYAIORGSA-N
分子式 Formula	C8H15NO6S
分子量 Molecular Weight	253.26
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	D-Ribose-L-cysteine(CAS:232617-15-1):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	D-Ribose-L-cysteine is a precursor to the antioxidant glutathione.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Falana B, Adeleke O, Orenolu M, Osinubi A, Oyewopo A. Effect of D-ribose-L-cysteine on aluminum induced testicular damage in male Sprague-Dawley rats. JBRA Assist Reprod. 2017 Jun 1;21(2):94-100. doi: 10.5935/1518-0557.20170023. PubMed PMID: 28609275; PubMed Central PMCID: PMC5473701.

[2]Saltman AE. D-ribose-L-cysteine supplementation enhances wound healing in a rodent model. Am J Surg. 2015 Jul;210(1):153-8. doi: 10.1016/j.amjsurg.2014.11.014. Epub 2015 Mar 27. PubMed PMID: 25935230.

[3] Kader T, Porteous CM, Williams MJ, Gieseg SP, McCormick SP. Ribose-cysteine increases glutathione-based antioxidant status and reduces LDL in human lipoprotein(a) mice. Atherosclerosis. 2014 Dec;237(2):725-33. doi: 10.1016/j.atherosclerosis.2014.10.101. Epub 2014 Nov 1. PubMed PMID: 25463112.

[4] Im GY, Kazi S, Thung SN, Perumalswami PV. A maxed-out liver: a case of acute-on-chronic liver failure. Semin Liver Dis. 2011 Nov;31(4):420-6. doi: 10.1055/s-0031-1297930. Epub 2011 Dec 21. PubMed PMID: 22189981.

[5] Jurkowska H, Uchacz T, Roberts J, Wróbel M. Potential therapeutic advantage of ribose-cysteine in the inhibition of astrocytoma cell proliferation. Amino Acids. 2011 Jun;41(1):131-9. doi: 10.1007/s00726-010-0593-4. Epub 2010 Apr 23. PubMed PMID: 20414692.

6: Oz HS, Chen TS, Nagasawa H. Comparative efficacies of 2 cysteine prodrugs and a glutathione delivery agent in a colitis model. Transl Res. 2007 Aug;150(2):122-9. Epub 2007 May 23. PubMed PMID: 17656332; PubMed Central PMCID: PMC1991291.7: Slitt AM, Dominick PK, Roberts JC, Cohen SD. Effect of ribose cysteine pretreatment on hepatic and renal acetaminophen metabolite formation and glutathione depletion. Basic Clin Pharmacol Toxicol. 2005 Jun;96(6):487-94. PubMed PMID: 15910414.8: Waldren CA, Vannais DB, Ueno AM. A role for long-lived radicals (LLR) in radiation-induced mutation and persistent chromosomal instability: counteraction by ascorbate and RibCys but not DMSO. Mutat Res. 2004 Jul 13;551(1-2):255-65. PubMed PMID: 15225598.9: Lenarczyk M, Ueno A, Vannais DB, Kraemer S, Kronenberg A, Roberts JC, Tatsumi K, Hei TK, Waldren CA. The "pro-drug" RibCys decreases the mutagenicity of high-LET radiation in cultured mammalian cells. Radiat Res. 2003 Nov;160(5):579-83. PubMed PMID: 14565824.10: Ueno A, Vannais D, Lenarczyk M, Waldren CA. Ascorbate, added after irradiation, reduces the mutant yield and alters the spectrum of CD59- mutations in A(L) cells irradiated with high LET carbon ions. J Radiat Res. 2002 Dec;43 Suppl:S245-9. PubMed PMID: 12793767.1

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