51484-40-3|Difenpiramide|(1,1'-Biphenyl)-4-acetamide, N-2-pyridinyl- (9CI)|-范德生物科技公司

Difenpiramide

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names：
(1,1'-Biphenyl)-4-acetamide, N-2-pyridinyl- (9CI)
CAS号：
51484-40-3
MDL Number：
MF(分子式)： C19H16N2O MW(分子量)： 288.35
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Difenpiramide
英文别名	Difenpiramide; Z-876
CAS号	51484-40-3
SMILES	C(Nc1ncccc1)(=O)Cc1ccc(cc1)c1ccccc1
Inchi	InChI=1S/C19H16N2O/c22-19(21-18-8-4-5-13-20-18)14-15-9-11-17(12-10-15)16-6-2-1-3-7-16/h1-13H,14H2,(H,20,21,22)
InchiKey	PWHROYKAGRUWDQ-UHFFFAOYSA-N
分子式 Formula	C19H16N2O
分子量 Molecular Weight	288.35
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Difenpiramide(CAS:51484-40-3):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Difenpiramide
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Varin T, Godfrey AG, Masquelin T, Nicolaou CA, Evans DA, Vieth M. Discovery of selective RIO2 kinase small molecule ligand. Biochim Biophys Acta. 2015 Oct;1854(10 Pt B):1630-6. doi: 10.1016/j.bbapap.2015.04.006. Epub 2015 Apr 17. PubMed PMID: 25891899.

[2]Lee DK, Shin JS. [A clinical study on the analgesic effectiveness of diphenpyramide in patients with orofacial pain following oral surgery]. Taehan Chikkwa Uisa Hyophoe Chi. 1987 Sep;25(9):873-83. Korean. PubMed PMID: 3507461.

[3] Jochems OB, Janbroers JM. Diphenpyramide: a review of its pharmacology and anti-inflammatory effects. Pharmatherapeutica. 1986;4(7):429-41. PubMed PMID: 3515370.

[4] Lunghi F, Blasi M, Frasson P, Lunghi M, Giusti P. [Evaluation of the therapeutic activity and tolerability of difenpiramide in otorhinolaryngology]. Clin Ter. 1982 Dec 31;103(6):635-45. Italian. PubMed PMID: 7160146.

[5] Cortini C, Campieri M, Brignola C, Bazzocchi G, Squillantini P. [Gastric tolerance of diphenpyramide after long-term treatment. Evaluation of the electric potential difference in the stomach]. Clin Ter. 1982 Dec 15;103(5):521-5. Italian. PubMed PMID: 7160144.

6: Dovigo L, Tartarini G, Cavalieri GP, Mazzi P, Cavilieri GP, Belluzzi D, Corazza G. [Clinical study of difenpiramide in the treatment of degenerative and inflammatory arthropathies]. Clin Ter. 1982 Apr 30;101(2):137-42. Italian. PubMed PMID: 7094545.7: Lorenzini P. [Clinical aspects and microcirculation findings in the treatment of arthrotic arthropathies with difenpiramide]. Minerva Med. 1981 Nov 14;72(45):3003-12. Italian. PubMed PMID: 7312201.8: Rainaldi P, Santoprete G. [Vertigo in vertebrobasilar insufficiency: experience with combined physical and pharmacological therapy]. Clin Ter. 1981 Aug 15;98(3):289-98. Italian. PubMed PMID: 7285539.9: Signorelli I, Garbarino G. [The use of difenpiramide in local or circumscribed inflammation in obstetrics and gynecology]. Clin Ter. 1981 Jul 15;98(1):37-46. Italian. PubMed PMID: 7249571.10: Trebbi A, Filippi G. Physicochemical profile of a new antiinflammatory drug: difenpiramide. Boll Chim Farm. 1979 Dec;118(12):729-38. PubMed PMID: 552255.1

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