72007-47-7|Crinia-angiotensin|L-Phenylalanine, N-(1-(N-(N-(N-(N-(N(2)-(N-(N-(1-L-alanyl-L-prolyl)glycyl)-L-alpha-aspartyl)-L-arginyl)-L-isoleucyl)-L-tyrosyl)-L-valyl)-L-histidyl)-L-prolyl)-|-范德生物科技公司

Crinia-angiotensin

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names：
L-Phenylalanine, N-(1-(N-(N-(N-(N-(N(2)-(N-(N-(1-L-alanyl-L-prolyl)glycyl)-L-alpha-aspartyl)-L-arginyl)-L-isoleucyl)-L-tyrosyl)-L-valyl)-L-histidyl)-L-prolyl)-
CAS号：
72007-47-7
MDL Number：
MF(分子式)： C60H66N16O15 MW(分子量)： 1271.46
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Crinia-angiotensin
英文别名	Crinia-angiotensin
CAS号	72007-47-7
Inchi	InChI=1S/C60H86N16O15/c1-6-33(4)49(74-50(81)39(15-10-22-65-60(62)63)69-51(82)41(28-47(79)80)68-46(78)30-66-53(84)44-16-11-23-75(44)57(88)34(5)61)56(87)70-40(25-36-18-20-38(77)21-19-36)52(83)73-48(32(2)3)55(86)71-42(27-37-29-64-31-67-37)58(89)76-24-12-17-45(76)54(85)72-43(59(90)91)26-35-13-8-7-9-14-35/h7-9,13-14,18-21,29,31-34,39-45,48-49,77H,6,10-12,15-17,22-28,30,61H2,1-5H3,(H,64,67)(H,66,84)(H,68,78)(H,69,82)(H,70,87)(H,71,86)(H,72,85)(H,73,83)(H,74,81)(H,79,80)(H,90,91)(H4,62,63,65)/t33-,34-,39-,40-,41-,42-,43-,44-,45-,48-,49-/m0/s1
InchiKey	RTJTXSIZQYTCMX-JMUWNTLFSA-N
分子式 Formula	C60H66N16O15
分子量 Molecular Weight	1271.46
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Crinia-angiotensin(CAS:72007-47-7):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Crinia-angiotensin is an Angiotensin II-like undecapeptide from skin of Australian frog Crinia georgiana.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Calabrese AN, Markulic K, Musgrave IF, Guo H, Zhang L, Bowie JH. Structural and activity changes in three bioactive anuran peptides when Asp is replaced by isoAsp. Peptides. 2012 Dec;38(2):427-36. doi: 10.1016/j.peptides.2012.10.00[1]Epub 2012 Oct 13. PubMed PMID: 23069634.

[2]Andreazza HJ, Wang T, Bagley CJ, Hoffmann P, Bowie JH. Negative ion fragmentations of deprotonated peptides. The unusual case of isoAsp: a joint experimental and theoretical study. Comparison with positive ion cleavages. Rapid Commun Mass Spectrom. 2009 Jul;23(13):1993-2002. doi: 10.1002/rcm.4107. PubMed PMID: 19489040.

[3] Denton DA, Blair-West JR, McBurnie M, Osborne PG, Tarjan E, Williams RM, Weisinger RS. Angiotensin and salt appetite of BALB/c mice. Am J Physiol. 1990 Oct;259(4 Pt 2):R729-35. PubMed PMID: 2221138.

[4] Siragy H, Howell N, Rose CE Jr, Khosla MC, Peach MJ, Carey RM. Intrarenal effects of [Ala-Pro-Gly-(Ile3-Val5)] angiotensin II in the conscious dog. Endocrinology. 1988 Jan;122(1):359-63. PubMed PMID: 3275540.

[5] Erspamer V, Erspamer GF, Mazzanti G, Endean R. Active peptides in the skins of one hundred amphibian species from Australia and Papua New Guinea. Comp Biochem Physiol C. 1984;77(1):99-108. PubMed PMID: 6141890.

6: Proto MC, Coviello A, Khosla MC, Bumpus FM. Effects of frog-skin angiotensin II in amphibians. Hypertension. 1983 Nov-Dec;5(6 Pt 3):V101-4. PubMed PMID: 6418648.7: Cantalamessa F, de Caro G, Massi M, Micossi LG. Drinking stimulation by a new angiotensin, crinia-angiotensin II, in rats and pigeons. Pharmacol Biochem Behav. 1982 Oct;17(4):741-7. PubMed PMID: 7178184.8: Khosla MC, Bumpus FM, Yasuhara T, Nakajima T. Synthesis of ala-pro-gly-[Ile3, Val5]angiotensin II isolated from the skin of the australian frog Crinia georgiana. J Med Chem. 1981 Jul;24(7):885-7. PubMed PMID: 7277399.9: Erspamer GF, Nakajima T, Yasuhara T. Pharmacological data on crinia-angiotensin II. J Pharm Pharmacol. 1979 Oct;31(10):720. PubMed PMID: 41055.10: Erspamer V, Melchiorri P, Nakajima T, Yasuhara T, Endean R. Amino acid composition and sequence of crinia-angiotensin, an angiotensin II-like endecapeptide from the skin of the Australian frog Crinia georgiana. Experientia. 1979 Sep 15;35(9):1132-3. PubMed PMID: 488254.

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