85287-61-2|Cefpimizole sodium|Pyridinium, 1-((2-carboxy-7-(((((5-carboxy-1H-imidazol-4-yl)carbonyl)amino)phenylacetyl)amino)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-4-(2-sulfoethyl)-, hydroxide, inner salt, monosodium salt, (6R-(6alpha,7beta(R*)))-|-范德生物科技公司

Cefpimizole sodium

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names：
Pyridinium, 1-((2-carboxy-7-(((((5-carboxy-1H-imidazol-4-yl)carbonyl)amino)phenylacetyl)amino)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-4-(2-sulfoethyl)-, hydroxide, inner salt, monosodium salt, (6R-(6alpha,7beta(R*)))-
CAS号：
85287-61-2
MDL Number：
MF(分子式)： C28H25N6NaO10S2 MW(分子量)： 692.65
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	Cefpimizole sodium
英文别名	Cefpimizole sodium; AC 1370 sodium; AC 1370; AC-1370; AC1370
CAS号	85287-61-2
SMILES	O=S(CCC1=CC=[N+](CC(CS[C@@]2([H])[C@H]3NC(C(NC(C4=C(C([O-])=O)NC=N4)=O)C5=CC=CC=C5)=O)=C(C(O)=O)N2C3=O)C=C1)([O-])=O.[Na+]
Inchi	InChI=1S/C28H26N6O10S2.Na/c35-23(18(16-4-2-1-3-5-16)31-24(36)19-20(27(38)39)30-14-29-19)32-21-25(37)34-22(28(40)41)17(13-45-26(21)34)12-33-9-6-15(7-10-33)8-11-46(42,43)44;/h1-7,9-10,14,18,21,26H,8,11-13H2,(H5-,29,30,31,32,35,36,38,39,40,41,42,43,44);/q;+1/p-1/t18?,21-,26-;/m0./s1
InchiKey	JLUNZNNMKVKUOH-YKGHYQGCSA-M
分子式 Formula	C28H25N6NaO10S2
分子量 Molecular Weight	692.65
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Cefpimizole sodium(CAS:85287-61-2):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Cefpimizole sodium is a Semisynthetic cephalosporin. It is an Antibacterial.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Periti P. Immunopharmacology of oral betalactams. J Chemother. 1998 Apr;10(2):91-6. Review. PubMed PMID: 9603632.

[2]Toyoguchi T, Nakagawa Y. [Nephrotoxicity and drug interaction of vancomycin (2)]. Nihon Yakurigaku Zasshi. 1996 May;107(5):225-35. Japanese. PubMed PMID: 8690304.

[3] Araki A, Sendo F. Reduced anti-Pseudomonas aeruginosa activity of a cephalosporin, cefodizime, in rats whose neutrophils were selectively depleted by a monoclonal antibody. Microbiol Immunol. 1996;40(5):333-8. PubMed PMID: 8999285.

[4] Ueta E, Yoneda K, Yamamoto T, Osaki T. Upregulatory effects of cefpimizole natrium on human leukocytes. Int J Immunopharmacol. 1992 Jul;14(5):877-85. PubMed PMID: 1324894.

[5] Nagano T, Ueno T, Mukai K, Yano S. [Case posing a therapeutic problem due to gastrointestinal hemorrhage caused by a factor VIII inhibitor following antibiotic administration]. Nihon Naika Gakkai Zasshi. 1991 Apr 10;80(4):619-20. Japanese. PubMed PMID: 1905741.

6: Ito K, Hayasaki M, Tamaya T. Pharmacokinetics of cephem antibiotics in exudate of pelvic retroperitoneal space after radical hysterectomy and pelvic lymphadenectomy. Antimicrob Agents Chemother. 1990 Jun;34(6):1160-4. PubMed PMID: 2393276; PubMed Central PMCID: PMC171777.7: Oishi K, Matsumoto K, Yamamoto M, Morito T, Yoshida T. Stimulatory effect of cefodizime on macrophage-mediated phagocytosis. J Antibiot (Tokyo). 1989 Jun;42(6):989-92. PubMed PMID: 2737956.8: Raad II, Sherertz RJ, Loveless MO, Carillo C, O'Connor RP, Miller M, Mostow SR. Comparison of cefpimizole with cefotaxime and penicillin G for treatment of uncomplicated gonorrhea. Sex Transm Dis. 1988 Apr-Jun;15(2):73-7. PubMed PMID: 3041630.9: Sato K, Saito H, Tomioka H. [In vitro and in vivo antimycobacterial activities of cefpimizole (AC-1370) and its effect on oxygen metabolism of host macrophages]. Kekkaku. 1988 Jan;63(1):19-25. Japanese. PubMed PMID: 3361739.10: Koga H. High-performance liquid chromatography measurement of antimicrobial concentrations in polymorphonuclear leukocytes. Antimicrob Agents Chemother. 1987 Dec;31(12):1904-8. PubMed PMID: 3439800; PubMed Central PMCID: PMC175825.1

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