32838-28-1|Butoctamide semisuccinate|4-((4-((2-ethylhexyl)amino)-4-oxobutan-2-yl)oxy)-4-oxobutanoic acid|-范德生物科技公司

Butoctamide semisuccinate

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names：
4-((4-((2-ethylhexyl)amino)-4-oxobutan-2-yl)oxy)-4-oxobutanoic acid
CAS号：
32838-28-1
MDL Number：
MF(分子式)： C16H29NO5 MW(分子量)： 315.41
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Butoctamide semisuccinate
英文别名	Butoctamide semisuccinate; M-2H; M 2H; M2H; Butoctamide hydrogen succinate;
CAS号	32838-28-1
Inchi	InChI=1S/C16H29NO5/c1-4-6-7-13(5-2)11-17-14(18)10-12(3)22-16(21)9-8-15(19)20/h12-13H,4-11H2,1-3H3,(H,17,18)(H,19,20)
InchiKey	CQONVBIGUJWUFE-UHFFFAOYSA-N
分子式 Formula	C16H29NO5
分子量 Molecular Weight	315.41
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Butoctamide semisuccinate(CAS:32838-28-1):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Butoctamide semisuccinate increases REM sleep in chronically prepared cats.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
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备注

[1]Sasaki K, Furusawa S, Takayanagi G. [Butoctamide enhancement of the antitumor activity of 6-mercaptopurine on Ehrlich solid tumors in mice (author's transl)]. Nihon Yakurigaku Zasshi. 1981 Feb;77(2):131-9. Japanese. PubMed PMID: 6894582.

[2]Mizuki Y, Suetsugi M, Hotta H, Ushijima I, Yamada M. Stimulatory effect of butoctamide hydrogen succinate on REM sleep in normal humans. Prog Neuropsychopharmacol Biol Psychiatry. 1995 May;19(3):385-401. PubMed PMID: 7624490.

[3] Grubar JC, Gigli GL, Colognola RM, Ferri R, Musumeci SA, Bergonzi P. Sleep patterns of Down's syndrome children: effects of butoctamide hydrogen succinate (BAHS) administration. Psychopharmacology (Berl). 1986;90(1):119-22. PubMed PMID: 2945221.

[4] Gigli GL, Grubar JC, Colognola RM, Amata MT, Pollicina C, Ferri R, Musumeci SA, Bergonzi P. Butoctamide hydrogen succinate and intensive learning sessions: effects on night sleep of Down's syndrome patients. Sleep. 1987 Dec;10(6):563-9. PubMed PMID: 2963363.

[5] Hayashi Y, Otomo E, Okudaira N, Endo S. Drug-increased REM sleep in aged subjects: butoctamide hydrogen succinate (BAHS). Psychopharmacology (Berl). 1982;77(4):367-70. PubMed PMID: 6813899.

6: Okudaira N, Torii S, Endo S. The effect of butoctamide hydrogen succinate on nocturnal sleep: all-night polygraphical studies. Psychopharmacology (Berl). 1980;70(2):117-21. PubMed PMID: 6776569.7: Tazaki T, Tada K, Nogami Y, Takemura N, Ishikawa K. Effects of butoctamide hydrogen succinate and nitrazepam on psychomotor function and EEG in healthy volunteers. Psychopharmacology (Berl). 1989;97(3):370-5. PubMed PMID: 2497487.8: Gigli GL, Grubar JC, Bergonzi P, Maschio MC. Long-term administration of butoctamide hydrogen succinate on nocturnal sleep of mentally retarded subjects: a polygraphic study versus placebo. Psychopharmacology (Berl). 1995 Feb;117(4):438-42. PubMed PMID: 7604145.9: Hayashi Y, Watanabe H, Okudaira N, Otomo E, Endo S. [The effects of butoctamide hydrogen succinate (BAHS) on the sleep of the aged people (author's transl)]. No To Shinkei. 1981 Dec;33(12):1243-50. Japanese. PubMed PMID: 7326156.10: Kato S, Wakasa Y, Yanagita T. [Dependence study on butoctamide hydrogen succinate (M-2H) in rhesus monkeys]. Arukoru Kenkyuto Yakubutsu Ison. 1987 Dec;22(4):340-51. Japanese. PubMed PMID: 3449033.1

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