34970-69-9|Burimamide|Burimamide|-范德生物科技公司

Burimamide

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names：
Burimamide
CAS号：
34970-69-9
MDL Number：
MF(分子式)： C9H16N4S MW(分子量)： 212.315
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Burimamide
英文别名	Burimamide
CAS号	34970-69-9
SMILES	S=C(NC)NCCCCC1=CNC=N1
Inchi	InChI=1S/C9H16N4S/c1-10-9(14)12-5-3-2-4-8-6-11-7-13-8/h6-7H,2-5H2,1H3,(H,11,13)(H2,10,12,14)
InchiKey	HXRBAVXGYZUSED-UHFFFAOYSA-N
分子式 Formula	C9H16N4S
分子量 Molecular Weight	212.315
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Burimamide(CAS:34970-69-9):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Burimamide is an antagonist of histamine that appears to block both H2 and H3 histamine receptors. It has been used in the treatment of ulcers.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Allan G, Eakins KE, Kulkarni PS, Levi R. Inhibition of thromboxane A2 biosynthesis in human platelets by burimamide. Br J Pharmacol. 1980;71(1):157-64. PubMed PMID: 6781572; PubMed Central PMCID: PMC2044402.

[2]Hough LB, Nalwalk JW, Leurs R, Menge WM, Timmerman H. Antinociceptive activity of derivatives of improgran and burimamide. Pharmacol Biochem Behav. 2000 Jan 1;65(1):61-6. PubMed PMID: 10638637.

[3] Harris DW, Smy JR, Reed JD, Venables CW. The effects of burimamide and metiamide on basal gastric function in the cat. Br J Pharmacol. 1975 Feb;53(2):293-7. PubMed PMID: 238700; PubMed Central PMCID: PMC1666291.

[4] Nowak JZ, Pilc A. The influence of mepyramine and burimamide on histamine induced catalepsy in the rat. Acta Physiol Pol. 1975 Sep-Oct;26(5):529-32. PubMed PMID: 1241504.

[5] Harris D, Smy JR, Reed JD, Venables CW. The effects of burimamide and metiamide on gastric secretion in the conscious cat. Agents Actions. 1974 Dec;4(5):311-3. PubMed PMID: 4463719.

6: Molinder HK. The development of cimetidine: 1964-1976. A human story. J Clin Gastroenterol. 1994 Oct;19(3):248-54. PubMed PMID: 7806839.7: Preiss DU, Code CF. Effect of the H2-receptor antagonists (burimamide and metiamide) on gastric secretion stimulated by histamine and its methyl derivatives. J Pharmacol Exp Ther. 1975 May;193(2):614-20. PubMed PMID: 238026.8: Ganellin CR, Owen DA. The pressor activity of burimamide: a relationship between chemical constitution and pressor activity of burimamide and related histamine H2-receptor antagonists. Agents Actions. 1977 Mar;7(1):93-6. PubMed PMID: 16463.9: Brandon JM, Wallis RM. Effect of mepyramine, a histamine H1-, and burimamide, a histamine H2-receptor antagonist, on ovum implantation in the rat. J Reprod Fertil. 1977 Jul;50(2):251-4. PubMed PMID: 881662.10: Brimblecombe RW, Duncan WA, Owen DA, Parsons ME. The pharmacology of burimamide and metiamide, two histamine H2-receptor antagonists. Fed Proc. 1976 Jun;35(8):1931-4. PubMed PMID: 5313.1

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