118587-22-7|BBR 2160|3,5-Pyridinedicarboxylic acid, 2-(((2-(formylamino)ethyl)thio)methyl)-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-, 3-ethyl 5-methyl ester|-范德生物科技公司

BBR 2160

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names：
3,5-Pyridinedicarboxylic acid, 2-(((2-(formylamino)ethyl)thio)methyl)-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-, 3-ethyl 5-methyl ester
CAS号：
118587-22-7
MDL Number：
MF(分子式)： C21H25N3O7S MW(分子量)： 463.5
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	BBR 2160
英文别名	BBR 2160; BBR-2160; BBR2160
CAS号	118587-22-7
Inchi	InChI=1S/C21H25N3O7S/c1-4-31-21(27)19-16(11-32-9-8-22-12-25)23-13(2)17(20(26)30-3)18(19)14-6-5-7-15(10-14)24(28)29/h5-7,10,12,18,23H,4,8-9,11H2,1-3H3,(H,22,25)
InchiKey	CLMNTOZRDYXVRT-UHFFFAOYSA-N
分子式 Formula	C21H25N3O7S
分子量 Molecular Weight	463.5
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	BBR 2160(CAS:118587-22-7):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	BBR 2160 is a dihydropyridine derivative belonging to the group of the so-called tiampidine that has calcium-antagonistic properties in cardiac tissue. Intracellular microelectrodes have been used to characterize the electrophysiological properties of BBR 2160 on sheep Purkinje fibres and guinea-pig papillary muscle. BBR 2160 (10(-7) and 10(-6) M) dose dependently decreased the contractility of driven Purkinje fibre and papillary muscle. This effect was associated with a lowering of the plateau phase and a shortening of action potential duration in papillary muscle.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Barbieri M, Masini I, Porciatti F, Cerbai E, Mugelli A. Cardiac electrophysiological effects of a new dihydropyridine calcium antagonist (BBR 2160). Pharmacol Res. 1991 Jan;23(1):87-94. PubMed PMID: 2047363.

[2]Barbieri M, Cerbai E, Masini I, Porciatti F, Visentin S, Mugelli A. Effect of BBR 2160 on ICa recorded from guinea-pig isolated myocytes. Pharmacol Res. 1990 Sep-Oct;22 Suppl

[3]121-2. PubMed PMID: 2097624.

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