165101-50-8|Alexomycin|(4S,4aS,5aS,6S,12aS)-7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carbimidic acid hydrochloride|-范德生物科技公司

Alexomycin

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names：
(4S,4aS,5aS,6S,12aS)-7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carbimidic acid hydrochloride
CAS号：
165101-50-8
MDL Number：
MF(分子式)： C22H24Cl2N2O8 MW(分子量)： 515.34
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Alexomycin
英文别名	165101-50-8
CAS号	165101-50-8
Inchi	InChI=1S/C22H23ClN2O8.ClH/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21;/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31);1H/t7-,8-,15-,21-,22-;/m0./s1
InchiKey	CBHYYLPALVVVEY-MRFRVZCGSA-N
分子式 Formula	C22H24Cl2N2O8
分子量 Molecular Weight	515.34
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Alexomycin(CAS:165101-50-8):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Alexomycin is a thiopeptide; a cyclic peptide antibiotic produced by Streptomyces arginensis isolated from the soil.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Marshall SA, Jones RN. Spectrum and antimicrobial activity of alexomycin (PNU-82, 127), a peptide compound projected for use in animal health. Diagn Microbiol Infect Dis. 1999 Mar;33(3):181-6. PubMed PMID: 10092967.

[2]Ashraf-Khorassani M, Taylor LT, Marr JG. Analysis of the sulfomycin component of alexomycin in animal feed by enhanced solvent extraction and supercritical fluid chromatography. J Biochem Biophys Methods. 2000 Jul 5;43(1-3):147-56. PubMed PMID: 10869673.

[3] Jones RN, Chen YS, Marshall SA. Comparative in vitro activity of alexomycin (U-82127) tested against Escherichia coli, Salmonella spp., and enterococci of animal and human origin. Clin Microbiol Infect. 1998;4(10):601-603. PubMed PMID: 11864251.

[4] Odland BA, Erwin ME, Jones RN. Quality control guidelines for disk diffusion and broth microdilution antimicrobial susceptibility tests with seven drugs for veterinary applications. J Clin Microbiol. 2000 Jan;38(1):453-5. PubMed PMID: 10618141; PubMed Central PMCID: PMC88749.

[5] Cho BY, Strong R, Fate G, Krull IS. High-performance capillary electrophoresis of a fermentation-derived cyclic peptide analog, animal growth promoter. J Chromatogr B Biomed Sci Appl. 1997 Sep 12;697(1-2):163-74. PubMed PMID: 9342666.

6: Cromwell GL, Davis GW, Morrow WE, Primo RA, Rozeboom DW, Sims MD, Stanisiewski EP, Ho CH. Efficacy of the antimicrobial compound U-82,127 as a growth promoter for growing-finishing pigs. J Anim Sci. 1996 Jun;74(6):1284-7. PubMed PMID: 8791200.

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