64-95-9|Adiphenine|Benzeneacetic acid, alpha-phenyl-, 2-(diethylamino)ethyl ester, (9CI)|-范德生物科技公司

Adiphenine

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names：
Benzeneacetic acid, alpha-phenyl-, 2-(diethylamino)ethyl ester, (9CI)
CAS号：
64-95-9
MDL Number：
MF(分子式)： C20H25NO2 MW(分子量)： 311.43
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Adiphenine
英文别名	Adiphenine;
CAS号	64-95-9
Inchi	InChI=1S/C20H25NO2/c1-3-21(4-2)15-16-23-20(22)19(17-11-7-5-8-12-17)18-13-9-6-10-14-18/h5-14,19H,3-4,15-16H2,1-2H3
InchiKey	JGOAIQNSOGZNBX-UHFFFAOYSA-N
分子式 Formula	C20H25NO2
分子量 Molecular Weight	311.43
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Adiphenine(CAS:64-95-9):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Adiphenine is an inhibitor of nicotinic receptors.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
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[2]Sun N, Zang W, Li W. Bioinformatics analysis reveals potential candidate drugs for psychological stress in ovarian cancer. Eur Rev Med Pharmacol Sci. 2012 Oct;16(10):1362-6. PubMed PMID: 23104652.

[3] Spitzmaul G, Gumilar F, Dilger JP, Bouzat C. The local anaesthetics proadifen and adiphenine inhibit nicotinic receptors by different molecular mechanisms. Br J Pharmacol. 2009 Jul;157(5):804-17. doi: 10.1111/j.1476-5381.2009.00214.x. Epub 2009 Apr 30. PubMed PMID: 19422391; PubMed Central PMCID: PMC2721265.

[4] Ortiz MI, Fernández-Martínez E, Pérez-Hernández N, Macías A, Rangel-Flores E, Ponce-Monter H. Patterns of prescription and self-medication for treating primary dysmenorrhea in a Mexican population. Proc West Pharmacol Soc. 2007;50:165-7. PubMed PMID: 18605257.

[5] Gentry CL, Lukas RJ. Local anesthetics noncompetitively inhibit function of four distinct nicotinic acetylcholine receptor subtypes. J Pharmacol Exp Ther. 2001 Dec;299(3):1038-48. PubMed PMID: 11714893.

6: Free RB, McKay DB. Receptor protection studies to characterize neuronal nicotinic receptors: tubocurarine prevents alkylation of adrenal nicotinic receptors. Brain Res. 2001 Feb 9;891(1-2):176-84. PubMed PMID: 11164821.7: Vargas G, Havel J, Babácková L, Patocka J. Determination of drugs used as anti-Parkinson's disease drugs in urine and serum by capillary electrophoresis. J Capillary Electrophor. 1998 May-Aug;5(3-4):153-8. PubMed PMID: 10797881.8: Lopez I, McKay DB. Effects of antimitotic agents on secretion and detergent extractibility of adrenal nicotinic acetylcholine receptors. Cell Mol Neurobiol. 1997 Oct;17(5):447-54. PubMed PMID: 9353587.9: Hayashi H, Fujii R. Pharmacological profiles of the subtypes of muscarinic cholinoceptors that mediate aggregation of pigment in the melanophores of two species of catfish. Pigment Cell Res. 1994 Jun;7(3):175-83. PubMed PMID: 7971751.10: Tong WQ, Lach JL, Chin TF, Guillory JK. Structural effects on the binding of amine drugs with the diphenylmethyl functionality to cyclodextrins. I. A microcalorimetric study. Pharm Res. 1991 Jul;8(7):951-7. PubMed PMID: 1924150.1

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