65372-80-7|AA560|Propanamide, 2-hydroxy-2-methyl-N-(3,4,5-trichlorophenyl)-|-范德生物科技公司

AA560

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names：
Propanamide, 2-hydroxy-2-methyl-N-(3,4,5-trichlorophenyl)-
CAS号：
65372-80-7
MDL Number：
MF(分子式)： C10H10Cl3NO2 MW(分子量)： 282.55
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	AA560
英文别名	AA560; AA-560; AA 560
CAS号	65372-80-7
SMILES	CC(C)(O)C(NC1=CC(Cl)=C(Cl)C(Cl)=C1)=O
Inchi	InChI=1S/C10H10Cl3NO2/c1-10(2,16)9(15)14-5-3-6(11)8(13)7(12)4-5/h3-4,16H,1-2H3,(H,14,15)
InchiKey	FVEPMRZJQUYLRA-UHFFFAOYSA-N
分子式 Formula	C10H10Cl3NO2
分子量 Molecular Weight	282.55
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	AA560(CAS:65372-80-7):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	AA560 is a nonsteroidal antiandrogen. AA560 decreases the uptake of 3H-androgens in the ventral prostate. AA560 decreases the weight of accessory organs.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Shida K, Yamanaka H, Koya A, Wakabayashi K, Mori H, Shibata K, Shimazawa E. Action of a novel nonsteroidal antiandrogen, AA560. Endocrinol Jpn. 1980 Feb;27(1):69-76. PubMed PMID: 6156070.

[2]Yoshida M, Asano M, Kaetsu I, Yamanaka H, Nakai K, Yuasa H, Shida K. Effect of drug-vinyl copolymer delivery composites on the rat prostate. J Biomed Mater Res. 1985 Jul-Aug;19(6):615-29. PubMed PMID: 2416759.

[3] Imai K, Takahashi O, Watanabe K, Nakazawa Y, Nakata S, Yamanaka H. [The effects of antiprostatic agents on the accessory sex organs of rats treated with adrenal androgens]. Hinyokika Kiyo. 1991 Dec;37(12):1669-76. Japanese. PubMed PMID: 1785391.

[4] Yamanaka H, Koya A, Imai K, Nakai K, Yuasa H, Sugiyama Y, Shida K, Wakabayashi K. Effect of AA560 (a nonsteroidal antiandrogen) implantation in the hypothalamus on gonadotropin secretion in male rats. Endocrinol Jpn. 1981 Dec;28(6):819-22. PubMed PMID: 6809452.

[5] Kim SY, Song KA, Kieff E, Kang MS. Small molecule and peptide-mediated inhibition of Epstein-Barr virus nuclear antigen 1 dimerization. Biochem Biophys Res Commun. 2012 Jul 27;424(2):251-6. doi: 10.1016/j.bbrc.2012.06.095. Epub 2012 Jun 23. PubMed PMID: 22735264.

6: Imai K, Watanabe K, Takahashi O, Shimizu N, Nakata S, Kawashima K, Suzuki T, Yamanaka H. [A study of the androgenic activity of anti-androgen]. Nihon Naibunpi Gakkai Zasshi. 1990 Jun 20;66(6):597-606. Japanese. PubMed PMID: 1696915.7: Takahashi O, Imai K, Watanabe K, Nakazawa Y, Nakata S, Kurita M, Saito Y, Kubota H, Yamanaka H. [The effect of sodium-4-[2-(2,3-dimethyl-4-[1-(4- isobutylphenyl)ethoxy]benzolamino)phenoxy] butyrate (ONO-3805) and antiandrogenic agents on the rat accessory sex organs]. Hinyokika Kiyo. 1992 Mar;38(3):305-10. Japanese. PubMed PMID: 1381863.8: Lapierre H, Doepel L, Milne E, Lobley GE. Responses in mammary and splanchnic metabolism to altered lysine supply in dairy cows. Animal. 2009 Mar;3(3):360-71. doi: 10.1017/S1751731108003571. PubMed PMID: 22444306.9: Anand SS, Murthy SN, Vaidya VS, Mumtaz MM, Mehendale HM. Tissue repair plays pivotal role in final outcome of liver injury following chloroform and allyl alcohol binary mixture. Food Chem Toxicol. 2003 Aug;41(8):1123-32. PubMed PMID: 12842180.10: Britt WJ, Jarvis MA, Drummond DD, Mach M. Antigenic domain 1 is required for oligomerization of human cytomegalovirus glycoprotein B. J Virol. 2005 Apr;79(7):4066-79. PubMed PMID: 15767408; PubMed Central PMCID: PMC1061566.1

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