127902-33-4|A71378|L-Phenylalaninamide, N-(1-oxo-3-(4-(sulfooxy)phenyl)propyl)-L-norleucylglycyl-L-tryptophyl-L-norleucyl-N-methyl-L-alpha-aspartyl-|-范德生物科技公司

A71378

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names：
L-Phenylalaninamide, N-(1-oxo-3-(4-(sulfooxy)phenyl)propyl)-L-norleucylglycyl-L-tryptophyl-L-norleucyl-N-methyl-L-alpha-aspartyl-
CAS号：
127902-33-4
MDL Number：
MF(分子式)： C48H62N8O13S MW(分子量)： 991.13
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

货品编码	规格	纯度	价格 (¥)	现价(¥)	特价(¥)	库存描述	数量	总计 (¥)
FMK10502-100mg	100mg	>98%	¥ 0.00	¥ 0.00		Get quote	- +	¥ 0.00

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中文别名	A71378
英文别名	A71378; A-71378; A 71378
CAS号	127902-33-4
Inchi	InChI=1S/C48H62N8O13S/c1-4-6-16-36(52-41(57)24-21-30-19-22-33(23-20-30)69-70(66,67)68)45(62)51-29-42(58)53-39(26-32-28-50-35-18-12-11-15-34(32)35)46(63)54-37(17-7-5-2)48(65)56(3)40(27-43(59)60)47(64)55-38(44(49)61)25-31-13-9-8-10-14-31/h8-15,18-20,22-23,28,36-40,50H,4-7,16-17,21,24-27,29H2,1-3H3,(H2,49,61)(H,51,62)(H,52,57)(H,53,58)(H,54,63)(H,55,64)(H,59,60)(H,66,67,68)/t36-,37-,38-,39-,40-/m0/s1
InchiKey	YJRSAZMDFOJHLB-HECCNADXSA-N
分子式 Formula	C48H62N8O13S
分子量 Molecular Weight	991.13
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	A71378(CAS:127902-33-4):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	A71378 is a Cholecystokinin (CCK) receptor agonist with high potency & selectivity for CCK-A receptors.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Davidowa H, Wetzel K, Henklein P. Neostriatal neurons of rats can be influenced by cholecystokinin-A receptor agonists. Neuropeptides. 1997 Jun;31(3):231-5. PubMed PMID: 9243519.

[2]Qian JM, Rowley WH, Jensen RT. Gastrin and CCK activate phospholipase C and stimulate pepsinogen release by interacting with two distinct receptors. Am J Physiol. 1993 Apr;264(4 Pt 1):G718-27. PubMed PMID: 8476056.

[3] Davidowa H, Wetzel K, Vierig G. Effects of cholecystokinin agonists on striatal neurons are reduced by acetylcholine. Peptides. 1997;18(4):541-5. PubMed PMID: 9210173.

[4] Giralt M, Vergara P. Inhibition by CCK of ascending contraction elicited by mucosal stimulation in the duodenum of the rat. Neurogastroenterol Motil. 2000 Apr;12(2):173-80. PubMed PMID: 10877605.

[5] Lin CW, Bianchi BR, Miller TR, Witte DG, Wolfram CA. Both CCK-A and CCK-B/gastrin receptors mediate pepsinogen release in guinea pig gastric glands. Am J Physiol. 1992 Jun;262(6 Pt 1):G1113-20. PubMed PMID: 1616041.

6: Lodge DJ, Lawrence AJ. Comparative analysis of the central CCK system in Fawn Hooded and Wistar Kyoto rats: extended localisation of CCK-A receptors throughout the rat brain using a novel radioligand. Regul Pept. 2001 Jun 15;99(2-3):191-201. PubMed PMID: 11384782.7: Heidel E, Davidowa H. Interactive effects of cholecystokinin-8S and serotonin on spontaneously active neurons in ventromedial hypothalamic slices. Neuropeptides. 1998 Oct;32(5):423-9. PubMed PMID: 9845002.8: Pradhan TK, Qian JM, Sutliff VE, Mantey SA, Jensen RT. Identification of CCK-A receptors on chief cells with use of a novel, highly selective ligand. Am J Physiol. 1995 Apr;268(4 Pt 1):G605-12. PubMed PMID: 7733286.9: Tang LH, Miller MD, Goldenring JR, Modlin IM, Hersey SJ. Partial agonism by gastrin for a cholecystokinin receptor mediating pepsinogen secretion. Am J Physiol. 1993 Nov;265(5 Pt 1):G865-72. PubMed PMID: 8238515.10: Rex A, Fink H. Effects of cholecystokinin-receptor agonists on cortical 5-HT release in guinea pigs on the X-maze. Peptides. 1998;19(3):519-26. PubMed PMID: 9533640.1

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