2058-52-8|Clothiapine|Dibenzo(b,f)(1,4)thiazepine, 2-chloro-11-(4-methyl-1-piperazinyl)-|-范德生物科技公司

Clothiapine

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names：
Dibenzo(b,f)(1,4)thiazepine, 2-chloro-11-(4-methyl-1-piperazinyl)-
CAS号：
2058-52-8
MDL Number：
MF(分子式)： C18H18ClN3S MW(分子量)： 343.873
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Clothiapine
英文别名	Clothiapine; HF 2159; HF-2159; HF2159; LW 2159; S-805C; W 130; Entumine
CAS号	2058-52-8
Inchi	InChI=1S/C18H18ClN3S/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3
InchiKey	KAAZGXDPUNNEFN-UHFFFAOYSA-N
分子式 Formula	C18H18ClN3S
分子量 Molecular Weight	343.873
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Clothiapine(CAS:2058-52-8):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Clothiapine, also known as Entumine, is an atypical antipsychotic of the dibenzothiazepine chemical class. It was first introduced in a few European countries (namely, Belgium, Italy, Spain and Switzerland), Argentina, Taiwan and Israel in 1970.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Mazhari S, Esmailian S, Shah-Esmaeili A, Goughari AS, Bazrafshan A, Zare M. Chlorpromazine versus clotiapine for schizophrenia. Cochrane Database Syst Rev. 2017 Apr 7;

4:CD011810. doi: 10.1002/14651858.CD011810.pub2. Review. PubMed PMID: 28387925.

[3]Claeys J, Bervoets C, De Fruyt J. [Clotiapine in the treatment of acutely agitated patients: hardly any evidence]. Tijdschr Psychiatr. 2017;59(3):175-180. Dutch. PubMed PMID: 28350145.

[4]Busardò FP, Mannocchi G, Pugnetti P, Santurro A, Maggiordomo A, Zaami S. A Very Unusual Accidental Mechanical Asphyxia of Choking with a Whole Solea Solea. J Forensic Sci. 2017 Mar;62(2):511-514. doi: 10.1111/1556-4029.13261. Epub 2016 Dec 6. PubMed PMID: 27921301.

[5] Lurie Y, Gopher A, Hoffmann Y, Bentur Y. Pediatric clotiapine poisoning: clinical manifestations and toxicokinetics. Am J Emerg Med. 2016 Dec;34(12):2469.e1-2469.e2. doi: 10.1016/j.ajem.2016.06.059. Epub 2016 Jun 16. PubMed PMID: 27567425.

5: Morini L, Vignali C, Tricomi P, Groppi A. Analytical Challenge in Postmortem Toxicology Applied to a Human Body Found into a Lake after Three Years Immersion. J Forensic Sci. 2015 Sep;60(5):1383-6. doi: 10.1111/1556-4029.12815. Epub 2015 Aug 10. PubMed PMID: 26258895.

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