6980-18-3|Kasugamycin|2-Amino-2-[(2R,3S,5S,6R)-5-amino-2-methyl-6-[(2S,3S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxyoxan-3-yl]iminoacetic acid|-范德生物科技公司

Kasugamycin

NMR下载 COA and HPLC MSDS下载
names：
2-Amino-2-[(2R,3S,5S,6R)-5-amino-2-methyl-6-[(2S,3S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxyoxan-3-yl]iminoacetic acid
CAS号：
6980-18-3
MDL Number：
MF(分子式)： C14H25N3O9 MW(分子量)： 379.36
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Kasugamycin
英文别名	Kasugamycin;
CAS号	6980-18-3
SMILES	O=C(O)/C(N)=N/[C@@H]1[C@@H](C)O[C@H](OC2[C@@H](O)[C@@H](O)C(O)[C@H](O)[C@H]2O)[C@@H](N)C1
Inchi	InChI=1S/C14H25N3O9/c1-3-5(17-12(16)13(23)24)2-4(15)14(25-3)26-11-9(21)7(19)6(18)8(20)10(11)22/h3-11,14,18-22H,2,15H2,1H3,(H2,16,17)(H,23,24)/t3-,4+,5+,6?,7+,8+,9-,10+,11?,14-/m1/s1
InchiKey	PVTHJAPFENJVNC-UQTMRZPGSA-N
分子式 Formula	C14H25N3O9
分子量 Molecular Weight	379.36
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility	Aqueous Base (Slightly), Water (Slightly)
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Kasugamycin(CAS:6980-18-3 ):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Kasugamycin is an antibiotic. It acts by binding within the mRNA channel of the 30S subunit and inhibiting protein synthesis.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Zhang H, Wang C, Li H, Nie Y, Fang L, Chen Z. Simultaneous determination of kasugamycin and validamycin-A residues in cereals by consecutive solid-phase extraction combined with liquid chromatography-tandem mass spectrometry. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2017 Dec 6. doi: 10.1080/19440049.2017.1411615. [Epub ahead of print] PubMed PMID: 29210618.

[2]Usachev KS, Ayupov RK, Validov SZ, Khusainov IS, Yusupov MM. NMR assignments of the N-terminal domain of Staphylococcus aureus hibernation promoting factor (SaHPF). Biomol NMR Assign. 2017 Oct 4. doi: 10.1007/s12104-017-9783-2. [Epub ahead of print] PubMed PMID: 28980143.

[3] Shiver AL, Osadnik H, Kritikos G, Li B, Krogan N, Typas A, Gross CA. Correction: A Chemical-Genomic Screen of Neglected Antibiotics Reveals Illicit Transport of Kasugamycin and Blasticidin S. PLoS Genet. 2017 Jul 21;13(7):e1006902. doi: 10.1371/journal.pgen.1006902. eCollection 2017 Jul. PubMed PMID: 28732023; PubMed Central PMCID: PMC5521741.

[4] Fan C, Guo M, Liang Y, Dong H, Ding G, Zhang W, Tang G, Yang J, Kong D, Cao Y. Pectin-conjugated silica microcapsules as dual-responsive carriers for increasing the stability and antimicrobial efficacy of kasugamycin. Carbohydr Polym. 2017 Sep 15;17

[5]322-331. doi: 10.1016/j.carbpol.2017.05.050. Epub 2017 May 21. PubMed PMID: 28606541.

5: Kasuga K, Sasaki A, Matsuo T, Yamamoto C, Minato Y, Kuwahara N, Fujii C, Kobayashi M, Agematu H, Tamura T, Komatsu M, Ishikawa J, Ikeda H, Kojima I. Heterologous production of kasugamycin, an aminoglycoside antibiotic from Streptomyces kasugaensis, in Streptomyces lividans and Rhodococcus erythropolis L-88 by constitutive expression of the biosynthetic gene cluster. Appl Microbiol Biotechnol. 2017 May;101(10):4259-4268. doi: 10.1007/s00253-017-8189-5. Epub 2017 Feb 27. PubMed PMID: 28243709.

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