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吲哚-3-羧酸
NMR and HPLC COA下载 MSDS下载 - Names：
Indole-3-carboxylic Acid
- CAS号：
771-50-6
MDL Number： MFCD00005624 - MF(分子式)： C9H7NO2 MW(分子量)： 161.16
- EINECS:212-231-6 Reaxys Number:
- Pubchem ID: Brand:BIOFOUNT
| 货品编码 | 规格 | 纯度 | 价格 (¥) | 现价(¥) | 特价(¥) | 库存描述 | 数量 | 总计 (¥) |
|---|---|---|---|---|---|---|---|---|
| JQ2519-500g | 500g | 99% | ¥ 1366.67 | ¥ 1366.67 | 1014 | Instock,1days | ¥ 0.00 | |
| JQ2519-100g | 100g | 99% | ¥ 454.67 | ¥ 454.67 | 339 | Instock,1days | ¥ 0.00 | |
| JQ2519-25g | 25g | 99% | ¥ 136.00 | ¥ 136.00 | 99 | Instock 1days | ¥ 0.00 | |
| JQ2519-5g | 5g | 99% | ¥ 72.00 | ¥ 72.00 | 51 | Instock 1days | ¥ 0.00 | |
| HCM76856-50g | 50g | 95% | ¥ 270.00 | ¥ 270.00 | 3-5days | ¥ 0.00 |
| 中文别名 | 吲哚-3-羧酸(771-50-6,Indole-3-carboxylic Acid);3-羧基吲哚;3-吲哚羧酸;3-甲酸吲哚;吲哚-3-甲酸 |
| 英文别名 | Indole-3-carboxylic Acid(CAS:771-50-6);1H-Indole-3-carboxylic acid;3-Indoleformic acid;3-Carboxyindole |
| CAS号 | 771-50-6 |
| Inchi | InChI=1S/C9H7NO2/c11-9(12)7-5-10-8-4-2-1-3-6(7)8/h1-5,10H,(H,11,12) |
| InchiKey | KMAKOBLIOCQGJP-UHFFFAOYSA-N |
| 分子式 Molecular Weight | C9H7NO2 |
| 分子量 Formula | 161.16 |
| 溶解度Solubility | DMSO : 100 mg/mL (620.50 mM; Need ultrasonic) |
| 性状 | 白色至灰白色固体粉末 |
| 储藏条件 Storage conditions | Store at 4°C,-4℃下存储更优 |
吲哚-3-羧酸(771-50-6,Indole-3-carboxylic Acid)实验注意事项：
1.使用771-50-6实验前需戴好防护眼镜，穿戴防护服和口罩，佩戴手套，避免与皮肤接触。
2.使用771-50-6实验过程中如遇到有毒或者刺激性物质及有害物质产生，必要时实验操作需要手套箱内完成以免对实验人员造成伤害。
3.取样品771-50-6的移液枪头需及时更换，必要时为避免交叉污染尽可能选择滤芯吸头。
4.称量药品时选用称量纸，并无风处取药和称量以免扬撒，试剂的容器使用前务必确保干净，并消毒。
5.取药品771-50-6时尽量采用多个药勺分别使用，使用后清洗干净。
6.实验后产生的废弃物需分类存储，并交于专业生物废气物处理公司处理，以免造成环境污染。
大规格定制：定制产品请将信息发送至sales@bio-fount.com。
Indole-3-carboxylic Acid(CAS:771-50-6) Experimental considerations:
1. Wear protective glasses, protective clothing and masks, gloves, and avoid contact with the skin during the experiment.
2. The waste generated after the experiment needs to be stored separately, and handed over to a professional biological waste gas treatment company to avoid environmental pollution.
Tag:吲哚-3-羧酸(771-50-6,Indole-3-carboxylic Acid),吲哚-3-羧酸试剂,吲哚-3-羧酸的作用,吲哚-3-羧酸的纯度,吲哚-3-羧酸的厂家,吲哚-3-羧酸的外观,吲哚-3-羧酸的溶解度,吲哚-3-羧酸的注意事项,吲哚-3-羧酸的储存条件,吲哚-3-羧酸的MSDS
| 产品说明 | 吲哚-3-羧酸(771-50-6,Indole-3-carboxylic Acid)仅限应用于科学研究中使用。771-50-6的熔点、771-50-6的MSDS等参数见主页。 |
| Introduction | Indole-3-carboxylic acid (771-50-6,吲哚-3-羧酸) is only used in scientific research. The melting point of 771-50-6 and the MSDS of 771-50-6 can be found on the homepage. |
| Application1 | Indole-3-carboxylic acid can be found in the roots of Carpesium abrotanoides. |
| Application2 | Reactant for preparation of:· Anticancer agents· Derivatives of amino acids and peptides· Serotonin 5-HT4 receptor antagonists· Primary acylureas· Inhibitors of Gli1-mediated transcription in the Hedgehog pathway· Serotonin 5-HT6 antagonists· Very Late Antigen-4 (VLA-4) sntagonists· EphB3 receptor tyrosine kinase inhibitors· Potential Therapeutic Agent for Alzheimer′s Disease· Vinyl ester pseudotripeptide proteasome inhibitors |
| Application3 |
| 警示图 | |
| 危险性 | warning |
| 危险性警示 | Not Available |
| 安全声明 | H303吞入可能有害+H313皮肤接触可能有害+H333吸入可能对身体有害 |
| 安全防护 | P264处理后彻底清洗+P280戴防护手套/穿防护服/戴防护眼罩/戴防护面具+P305如果进入眼睛+P351用水小心冲洗几分钟+P338取出隐形眼镜（如果有）并且易于操作,继续冲洗+P337如果眼睛刺激持续+P313获得医疗建议/护理 |
| 备注 | 避免吸入，误食以及与皮肤接触 |
| 象形图 |  |
|---|---|
| 信号 | Warning |
| GHS危险说明 |
Aggregated GHS information provided by 10 companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H302 (40%): Harmful if swallowed [Warning Acute toxicity, oral] H312 (20%): Harmful in contact with skin [Warning Acute toxicity, dermal] H315 (90%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (90%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (80%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
| 防范说明代码 |
P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Lasiodiplodia sp. ME4-2, an endophytic fungus from the floral parts of Viscum coloratum, produces indole-3-carboxylic acid and other aromatic metabolites(BMC Microbiology,2014) |
| Ethylene Induced Changes in Auxin Metabolism in Citrus Leaf Tissues(Biochemical and Physiological Aspects of Ethylene Production in Lower and Higher Plants,1989) |
| Biosynthesis and metabolism of indole-3-ethanol and indole-3-acetic acid by Pinus sylvestris L. needles(Planta,1984) |
| Free radical-scavenging activity of indolic compounds in aqueous and ethanolic media(Analytical and Bioanalytical Chemistry,2003) |
| Synthesis of di- and trisubstituted 1,2,4-triazoles containing indole fragments(Chemistry of Heterocyclic Compounds,1993) |
1.Biosynthesis and metabolism of indole-3-ethanol and indole-3-acetic acid by Pinus sylvestris L. needles.
Sandberg G Planta. 1984 Jul;161(5):398-403. doi: 10.1007/BF00394569.
Combined gas chromatography-mass spectrometry has been used to identify indole-3-ethanol (IEt) in a purified extract from needles of Pinus sylvestris L. Quantitative estimates obtained by high-performance liquid chromatography with fluorescence detection, corrected for samples losses occurring during purification, indicate that Pinus needles contain 46±4 ng g(-1) IEt. This compares with 24.5±6.5 ng g(-1) indole-3-acetic acid (IAA) and 2.3±0.4 ng g(-1) indole-3-carboxylic acid (ICA) (Sandberg et al. 1984, Phytochemistry, 23, 99-102). Metabolism studies with needles incubated in a culture medium in darkness revealed that both [3-(14)C]-tryptophan and [2-(14)C]tryptamine mine are converted to [(14)C]IEt. It was also shown that [3-(14)C]IEt acted as a precursor of [(14)C]IAA. The observed metabolism appears to be enzymic in nature. The [2-(14)C]IAA was not catabolised to [(14)C]ICA in detectable quantities implying that, at best, only a minor portion of the endogenous ICA pool in the Pinus needles originates from IAA.
2.Gas chromatographic analysis of acidic indole auxins in Nicotiana.
Bayer MH Plant Physiol. 1969 Feb;44(2):267-71.
Acidic indole auxins have been extracted from N. glauca, N. langsdorffii and their 2 tumor-prone 4n- and 2n-hybrids. After purification of the extracts and thin-layer chromatography, acidic indoles were subjected to esterification and gas chromatography. The esters of 4 indole acids were detected and determined: indole-3-acetic acid, indole-3-carboxylic acid, indole-3-propionic acid and indole-3-butyric acid. The indolic nature of fractionated samples was confirmed by spectrophotofluorometry and the physiological significance of the indole esters proven in a biotest. A substantial increase in extractable indole-3-butyric acid in the tumor-prone hybrids suggests an additional pathway of auxin synthesis in these tissues.
3.Mutagen formation on nitrite treatment of indole compounds derived from indole-glucosinolate.
Sasagawa C;Matsushima T Mutat Res. 1991 Sep-Oct;250(1-2):169-74.
The mutagenicities of 8 indole compounds (indole-3-acetonitrile, indole-3-carbinol, indole-3-acetamide, indole-3-acetic acid, 3-methylindole, indole-3-aldehyde, indole-3-carboxylic acid and indole) derived from indole glucosinolate were studied by mutation tests on Salmonella typhimurium TA98 and TA100 and Escherichia coli WP2 uvrA/pKM101 with and without S9 mix. None of the 8 indole compounds were mutagenic, but they became mutagenic on these 3 tester strains when treated with nitrite at pH 3. The nitrite-treated indole compounds were mutagenic without metabolic activation system (S9 mix), and their mutagenicities were decreased by the addition of S9 mix.
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