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植物凝胶
NMR and HPLC COA下载 MSDS下载 - Names：
Gellan Gum
- CAS号：
71010-52-1
MDL Number： MFCD00131909 - MF(分子式)： MW(分子量)：
- EINECS:275-117-5 Reaxys Number:
- Pubchem ID: Brand:BIOFOUNT
植物凝胶(71010-52-1,Gellan Gum)在植物组织培养基中工作浓度为1.5-2.5 g/L，植物凝胶在微生物培养基中工作浓度为10 g/L。植物凝胶需要阳离子(特别是二价阳离子)存在才能使胶凝固。
| 货品编码 | 规格 | 纯度 | 价格 (¥) | 现价(¥) | 特价(¥) | 库存描述 | 数量 | 总计 (¥) |
|---|---|---|---|---|---|---|---|---|
| SS6181-25g | 25g | 生物技术级 | ¥ 128.00 | ¥ 128.00 | Instock | ¥ 0.00 | ||
| SS6181-250g | 250g | 生物技术级 | ¥ 618.00 | ¥ 618.00 | Instock | ¥ 0.00 | ||
| SS6181-50g | 50g | 生物技术级 | ¥ 198.00 | ¥ 198.00 | Instock | ¥ 0.00 | ||
| SS6181-5g | 5g | 生物技术级 | ¥ 48.00 | ¥ 48.00 | Instock | ¥ 0.00 |
| 中文别名 | 植物凝胶,植物凝胶(71010-52-1,Gellan Gum);冷结树酯;结冷胶;凯可胶 |
| 英文别名 | Gellan Gum(71010-52-1);Phytagel;Agar substitute gelling agent |
| CAS号 | 71010-52-1 |
| Inchi | No data available |
| InchiKey | No data available |
| 分子式 Molecular Weight | |
| 分子量 Formula | |
| 溶解度Solubility | 溶于水，不溶于乙醇 |
| 性状 | 白色或类白色固体粉末 |
| 储藏条件 Storage conditions | 室温保存 |
植物凝胶(71010-52-1,Gellan Gum)实验注意事项：
1.实验前需戴好防护眼镜，穿戴防护服和口罩，佩戴手套，避免与皮肤接触。
2.实验过程中如遇到有毒或者刺激性物质及有害物质产生，必要时实验操作需要手套箱内完成以免对实验人员造成伤害。
3.取样品的移液枪头需及时更换，必要时为避免交叉污染尽可能选择滤芯吸头。
4.称量药品时选用称量纸，并无风处取药和称量以免扬撒，试剂的容器使用前务必确保干净，并消毒。
5.取药品时尽量采用多个药勺分别使用，使用后清洗干净后，烘干消毒存放。
6.实验后产生的废弃物需分类存储，并交于专业生物废气物处理公司处理，以免造成环境污染。
Gellan Gum(71010-52-1) Experimental considerations:
1. Wear protective glasses, protective clothing and masks, gloves, and avoid contact with the skin during the experiment.
2. The waste generated after the experiment needs to be stored separately, and handed over to a professional biological waste gas treatment company to avoid environmental pollution.
Tag:植物凝胶(71010-52-1,Gellan Gum),植物凝胶的含量,植物凝胶的作用,植物凝胶的保存条件,植物凝胶的外观,植物凝胶的使用注意事项,植物凝胶的厂家,植物凝胶的成分,植物凝胶的价格
| 产品说明 | 植物凝胶(71010-52-1,Gellan Gum)用于科学研究使用,植物凝胶的作用,植物凝胶的价格见主页。 |
| Introduction | Gellan Gum (71010-52-1,植物凝胶) is used in scientific research. See the homepage for the function of Gellan Gum and the price of Gellan Gum. |
| Application1 | 本产品应用于Gellan Gum is an agar substitute and gelling agent, and useful in a wide variety of immobilization matricies.注释Incompatible with oxidizing agents. |
| Application2 | |
| Application3 |
| 警示图 | |
| 危险性 | warning |
| 危险性警示 | No data available |
| 安全声明 | H303吞入可能有害+H313皮肤接触可能有害+H333吸入可能对身体有害 |
| 安全防护 | P264处理后彻底清洗+P280戴防护手套/穿防护服/戴防护眼罩/戴防护面具+P305如果进入眼睛+P351用水小心冲洗几分钟+P338取出隐形眼镜（如果有）并且易于操作,继续冲洗+P337如果眼睛刺激持续+P313获得医疗建议/护理 |
| 备注 | 避免吸入，误食以及与皮肤接触 |
| Ion activated in situ gel of gellan gum containing salbutamol sulphate for nasal administration. |
| Modification of gellan gum with nanocrystalline hydroxyapatite facilitates cell expansion and spontaneous osteogenesis. |
| High-resolution synchrotron X-ray analysis of bioglass-enriched hydrogels. |
| Two new nontoxic, non-pathogenic strains of Sphingomonas elodea for gellan gum production. |
1.Ion activated in situ gel of gellan gum containing salbutamol sulphate for nasal administration.
Salunke SR1, Patil SB2. Int J Biol Macromol. 2016 Jun;87:41-7. doi: 10.1016/j.ijbiomac.2016.02.044. Epub 2016 Feb 17.
Nasal delivery is the promising approach for rapid onset of action and avoids the first pass metabolism. The main aim of present study was to develop a novel mucoadhesive in situ gel of salbutamol sulphate using gellan gum and hydroxylpropyl methyl cellulose (HPMC) for nasal administration. The formulations were prepared so as to have gelation at physiological ion content after nasal administration. Developed formulations were evaluated for gelation, viscosity, drug content, in vitro mucoadhesion, in vitro drug release study, ex vivo permeation, and histopathology. Formulations showed pH in the range of nasal cavity and optimum viscosity for nasal administration. The mucoadhesive force depends upon concentration of HPMC and drug release was found to be 97.34% in 11h. The histopathology did not detect any damage during ex vivo permeation studies. Hence, in situ gel system of gellan gum may be a promising approach for nasal delivery of salbutamol sulphate for therapeutic improvement.
2.Modification of gellan gum with nanocrystalline hydroxyapatite facilitates cell expansion and spontaneous osteogenesis.
Jamshidi P1, Birdi G2, Williams RL2, Cox SC2, Grover LM2. Biotechnol Bioeng. 2015 Dec 24. doi: 10.1002/bit.25915. [Epub ahead of print]
Nanocomposites composed of hydrogels and calcium phosphates are of great interest in the development of bone graft replacements since they may have a structural and compositional resemblance to bone. Culture beads formed from such materials could be used in stirred tank culture and thereby enable cell expansion in a sufficiently efficient manner to allow for the generation of enough large number of cells for large-scale bone reconstruction. Although combinations of materials such as alginate, collagens and various calcium phosphates have been investigated as culture beads, these materials are unsuitable for application since they have been shown to rapidly degrade in physiological conditions and enable relatively little tailoring of mechanical properties. In this study, gellan gum-nano sized hydroxyapatite (nHA) composites, which have been shown to be resistant to degradation and easily modified with respect to modulus, were formulated and characterised as regards their ability to enable cell attachment and proliferation.
3.High-resolution synchrotron X-ray analysis of bioglass-enriched hydrogels.
Gorodzha S1, Douglas TE2, Samal SK3, Detsch R4, Cholewa-Kowalska K5, Braeckmans K3, Boccaccini AR4, Skirtach AG2, Weinhardt V6, Baumbach T7, Surmeneva MA1, Surmenev RA1,8. J Biomed Mater Res A. 2016 May;104(5):1194-201. doi: 10.1002/jbm.a.35642. Epub 2016 Feb 5.
Enrichment of hydrogels with inorganic particles improves their suitability for bone regeneration by enhancing their mechanical properties, mineralizability, and bioactivity as well as adhesion, proliferation, and differentiation of bone-forming cells, while maintaining injectability. Low aggregation and homogeneous distribution maximize particle surface area, promoting mineralization, cell-particle interactions, and homogenous tissue regeneration. Hence, determination of the size and distribution of particles/particle agglomerates in the hydrogel is desirable. Commonly used techniques have drawbacks. High-resolution techniques (e.g., SEM) require drying. Distribution in the dry state is not representative of the wet state. Techniques in the wet state (histology, µCT) are of lower resolution. Here, self-gelling, injectable composites of Gellan Gum (GG) hydrogel and two different types of sol-gel-derived bioactive glass (bioglass) particles were analyzed in the wet state using Synchrotron X-ray radiation, enabling high-resolution determination of particle size and spatial distribution.
4.Two new nontoxic, non-pathogenic strains of Sphingomonas elodea for gellan gum production.
Dolan LC1, Matulka RA2, LeBeau AL2, Boulet JM3. Regul Toxicol Pharmacol. 2016 Apr 11. pii: S0273-2300(16)30070-8. doi: 10.1016/j.yrtph.2016.04.002. [Epub ahead of print]
Two new strains of Sphingomonas elodea (designated as PHP1 and PBAD1) were tested for toxicity and pathogenicity in healthy Sprague-Dawley CD® IGS rats in separate studies. In each study, twelve rats/sex were administered ≥108 viable cells/rat by oral gavage, and four untreated rats/sex served as controls. Blood, feces, and selected organs/tissues collected at various times over the course of the 22 day study were evaluated for the presence of PHP1 or PBAD1 (depending on the study) by a validated method, to determine the potential for survival, propagation, or infectivity of PHP1 and PBAD1 cells in the rat. No mortalities, test substance-related changes in clinical or macroscopic findings, body weight or body weight gain were observed in treated animals compared with controls, indicating a lack of toxicity. PHP1 or PBAD1 were not detected in the tissue, fecal or fluid samples collected from treated animals. Therefore, neither PHP1 nor PBAD1 were pathogenic or acutely toxic under the conditions of the studies.
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