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苯甲酸
NMR and HPLC COA下载 MSDS下载 - Names：
Benzoic acid
- CAS号：
65-85-0
MDL Number： MFCD00002398 - MF(分子式)： C7H6O2 MW(分子量)： 122.12
- EINECS:200-618-2 Reaxys Number:
- Pubchem ID: Brand:BIOFOUNT
苯甲酸(65-85-0,Benzoic acid)是白色至灰白色固体，也称为苯甲酸酯或E210，属于称为苯甲酸的有机化合物。 苯甲酸以固体，微溶（在水中）和弱酸性化合物（基于其pKa）存在。 在大多数人体组织中均发现了苯甲酸，并且在包括唾液，粪便，尿液和汗液在内的大多数生物流体中也发现了苯甲酸。 在细胞内，苯甲酸主要位于细胞质和内质网中。 从酵母到人类，所有真核生物中均存在苯甲酸。 苯甲酸还是其他转化产物的母体化合物，包括但不限于4-（2-羧苯基）-2-氧代丁-3-烯酸，4-羟基-3-辛烯基苯甲酸和羟基苯甲酸。 苯甲酸是一种潜在的有毒化合物。
| 货品编码 | 规格 | 纯度 | 价格 (¥) | 现价(¥) | 特价(¥) | 库存描述 | 数量 | 总计 (¥) |
|---|---|---|---|---|---|---|---|---|
| HCM73825-1g | 1g | 95% | ¥ 0.00 | ¥ 0.00 | Get quote | ¥ 0.00 | ||
| JT22946-250g | 250g | ≥99% | ¥ 52.00 | ¥ 52.00 | 3-6days | ¥ 0.00 |
| 中文别名 | 苯甲酸(65-85-0,Benzoic acid);安息香酸;安息酸;苯酸 |
| 英文别名 | Benzoic acid(65-85-0);Dracylic acid;benzenecarboxylic acid;Carboxybenzene |
| CAS号 | 65-85-0 |
| Inchi | InChI=1S/C7H6O2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H,8,9) |
| InchiKey | WPYMKLBDIGXBTP-UHFFFAOYSA-N |
| 分子式 Molecular Weight | C7H6O2 |
| 分子量 Formula | 122.12 |
| 溶解度Solubility | DMSO : ≥ 100 mg/mL (818.87 mM) H2O : 7.14 mg/mL (58.47 mM; Need ultrasonic) |
| 性状 | 白色至灰白色固体粉末 |
| 储藏条件 Storage conditions | storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years) |
苯甲酸(65-85-0,Benzoic acid)毒性测试：
| 生物 | 测试类型 | 路线 | 报告剂量（标准化剂量） | 影响 | 参考 |
|---|---|---|---|---|---|
| frog | LDLo | subcutaneous | 100mg/kg (100mg/kg) | "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 5, Pg. 23, 1959. | |
| guinea pig | LDLo | intraperitoneal | 1400mg/kg (1400mg/kg) | "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 5, Pg. 23, 1959. | |
| guinea pig | LDLo | oral | 2gm/kg (2000mg/kg) | Muenchener Medicinische Wochenschrift. Vol. 77, Pg. 13, 1930. | |
| human | TDLo | skin | 6mg/kg (6mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA SKIN AND APPENDAGES (SKIN): "DERMATITIS, ALLERGIC: AFTER SYSTEMIC EXPOSURE" |
Journal of Allergy. Vol. 16, Pg. 195, 1945. |
| man | LDLo | oral | 500mg/kg (500mg/kg) | Food and Cosmetics Toxicology. Vol. 17, Pg. 715, 1979. | |
| mouse | LD50 | intraperitoneal | 1460mg/kg (1460mg/kg) | Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 160, Pg. 1097, 1966. | |
| mouse | LD50 | oral | 1940mg/kg (1940mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION GASTROINTESTINAL: OTHER CHANGES |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 15, Pg. 359, 1984. |
| rabbit | LD50 | skin | > 10gm/kg (10000mg/kg) | BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 28-4/1973, | |
| rabbit | LDLo | oral | 2gm/kg (2000mg/kg) | "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 5, Pg. 23, 1959. | |
| rabbit | LDLo | subcutaneous | 2gm/kg (2000mg/kg) | "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 5, Pg. 23, 1959. | |
| rat | LC50 | inhalation | > 26mg/m3/1H (26mg/m3) | SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) |
BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 28-4/1973, |
| rat | LD50 | intraperitoneal | 1600mg/kg (1600mg/kg) | Bollettino Chimico Farmaceutico. Vol. 112, Pg. 53, 1973. | |
| rat | LD50 | intravenous | 1700mg/kg (1700mg/kg) | Acta Physiologica Polonica. Vol. 12, Pg. 173, 1961. | |
| rat | LD50 | oral | 1700mg/kg (1700mg/kg) | International Polymer Science and Technology. Vol. 3, Pg. 93, 1976. |
苯甲酸(65-85-0,Benzoic acid)实验注意事项：
1.使用65-85-0实验前需戴好防护眼镜，穿戴防护服和口罩，佩戴手套，避免与皮肤接触。
2.使用65-85-0实验过程中如遇到有毒或者刺激性物质及有害物质产生，必要时实验操作需要手套箱内完成以免对实验人员造成伤害。
3.取样品65-85-0的移液枪头需及时更换，必要时为避免交叉污染尽可能选择滤芯吸头。
4.称量药品时选用称量纸，并无风处取药和称量以免扬撒，试剂的容器使用前务必确保干净，并消毒。
5.取药品65-85-0时尽量采用多个药勺分别使用，使用后清洗干净。
6.实验后产生的废弃物需分类存储，并交于专业生物废气物处理公司处理，以免造成环境污染。
大规格定制：定制产品请将信息发送至sales@bio-fount.com。
Benzoic acid(65-85-0) Experimental considerations:
1. Wear protective glasses, protective clothing and masks, gloves, and avoid contact with the skin during the experiment.
2. The waste generated after the experiment needs to be stored separately, and handed over to a professional biological waste gas treatment company to avoid environmental pollution.
Tag:苯甲酸(65-85-0,Benzoic acid),苯甲酸试剂,苯甲酸抑制剂,苯甲酸的价格,苯甲酸的外观,苯甲酸的纯度,苯甲酸的合成,苯甲酸的溶解度,苯甲酸的成分,苯甲酸的厂家,苯甲酸的作用,苯甲酸的毒性,苯甲酸的注意事项,苯甲酸的MSDS,苯甲酸的生产
| 产品说明 | 苯甲酸(65-85-0)是一种白色至灰白色结晶固体,是一种简单的芳香族羧酸,苯甲酸用作食品防腐剂.苯甲酸溶解度,苯甲酸msds,苯甲酸结构式详见主页. |
| Introduction | Benzoic acid (65-85-0,苯甲酸) is a white to off-white crystalline solid. It is a simple aromatic carboxylic acid used as a food preservative. |
| Application1 | 苯甲酸(65-85-0,Benzoic acid)通过抑制细菌和真菌作为防腐剂。 |
| Application2 | 苯甲酸是EC 3.1.1.3（三酰甘油脂肪酶）抑制剂，也是EC 1.13.11.33（花生四烯酸15-脂加氧酶）抑制剂 |
| Application3 | 苯甲酸(65-85-0,Benzoic acid)可以用作碘定量标准，碱定量标准等 |
Benzoic acid (65-85-0,苯甲酸), also known as benzoate or E210, belongs to the class of organic compounds known as benzoic acids. These are organic Compounds containing a benzene ring which bears at least one carboxyl group. Benzoic acid exists as a solid, slightly soluble (in water), and a weakly acidic compound (based on its pKa). Benzoic acid has been found throughout most human tissues, and has also been detected in most biofluids, including saliva, feces, urine, and sweat. Within the cell, benzoic acid is primarily located in the cytoplasm and endoplasmic reticulum. Benzoic acid exists in all eukaryotes, ranging from yeast to humans. Benzoic acid is also a parent compound for other transformation products, including but not limited to, 4-(2-carboxyphenyl)-2-oxobut-3-enoic acid, 4-hydroxy-3-octaprenylbenzoic acid, and hydroxybenzoic acid. Benzoic acid is a potentially toxic compound.
| 警示图 | |
| 危险性 | warning |
| 危险性警示 | Not Available |
| 安全声明 | H302,H319 |
| 安全防护 | P305+P351+P338 |
| 备注 | 避免吸入，误食以及与皮肤接触 |
| 象形图 |    |
|---|---|
| 信号警告 | Danger |
| GHS危险说明 |
H315: Causes skin irritation [Warning Skin corrosion/irritation] H318: Causes serious eye damage [Danger Serious eye damage/eye irritation] H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] |
| 防范说明代码 |
P260, P264, P270, P280, P302+P352, P305+P351+P338, P310, P314, P321, P332+P313, P362, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Magnetism and white-light-emission bifunctionality simultaneously assembled into flexible Janus nanofiber via electrospinning(Journal of Materials Science,2015) |
| Facile electrospinning construction and characteristics of coaxial nanobelts with simultaneously tunable magnetism and color-tuned photoluminescence bifunctionality |
| One-pot facile electrospinning construct of flexible Janus nanofibers with tunable and enhanced magnetism–photoluminescence bifunctionality |
| A novel scheme to obtain tunable fluorescent colors based on electrospun composite nanofibers(Journal of Materials Science: Materials in Electronics,2014) |
| Dy3+ and Eu3+ complexes co-doped flexible composite nanofibers to achieve tunable fluorescent color(Journal of Materials Science: Materials in Electronics,2015) |
Induction of functional cytochrome P450 and its involvement in degradation of benzoic acid by Phanerochaete chrysosporium
Abstract:The white rot fungus Phanerochaete chrysosporium has the largest cytochrome P450 contingent known to date in fungi, but the study on the function of these P450s is limited. In this study, induction of functional P450 in P. chrysosporium was first shown and P450-mediate degradation of benzoic acid was demonstrated in this fungus. Carbon monoxide difference spectra indicated significant induction of P450 by benzoic acid, m-chlorobenzoic acid, p-chlorobenzoic acid and n-hexane, and showed the effect of inducer concentration and nutrient condition on the induction of P450. The high contents of P450 in the microsomal fractions facilitated the study on the function of P450. While the n-hexane-induced P450 could not interact with benzoic acid, the microsomal P450 induced by benzoic acid produced type I substrate binding spectra upon the addition of benzoic acid. The benzoic acid degradation by the microsomal P450 was NADPH-dependent at a specific rate of 194 ± 14 min−1, and significantly inhibited by piperonyl butoxide (a P450 inhibitor). However, inhibition of benzoic acid degradation by piperonyl butoxide was slight or not detectable in the cultures of this fungus, suggesting presumable involvement of other enzyme in benzoic acid degradation. The extracellular ligninolytic enzymes, lignin peroxidase and manganese-dependent peroxidase, were not involved in initial metabolism of benzoic acid under the test conditions.
Online dynamic pH junction–sweeping for the determination of benzoic and sorbic acids in food products by capillary electrophoresis
Abstract:A simple, low-cost, and efficient online focusing method that combines a dynamic pH junction and sweeping by capillary electrophoresis with polymer solutions was developed and optimized for the simultaneous determination of benzoic acid (BA) and sorbic acid (SA). A sample solution consisting of 2.5 mM phosphate at pH 3.0 and a buffer solution containing 15 mM tetraborate (pH 9.2), 40 mM sodium dodecyl sulfate, and 0.100 % (w/v) poly(ethylene oxide) were utilized to realize dynamic pH junction–sweeping for BA and SA. Under the optimized conditions, the entire analysis process was completed in 7 min, and a 900-fold sensitivity enhancement was achieved with limits of detection (S/N = 3) as low as 8.2 and 6.1 nM for BA and SA, respectively. The linear ranges were between 20 nM and 20 μM for BA and 20 nM and 10 μM for SA, with correlation coefficients greater than 0.992. The recoveries of the proposed method ranged from 90 to 113 %. These satisfactory results indicate that this method has the potential to be an effective analytical tool for the rapid screening of BA and SA in different food products.???????
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