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亚油酸
NMR and HPLC COA下载 MSDS下载 - Names：
Linoleic acid
- CAS号：
60-33-3
MDL Number： MFCD00064241 - MF(分子式)： C18H32O2 MW(分子量)： 280.45
- EINECS:200-470-9 Reaxys Number:
- Pubchem ID: Brand:BIOFOUNT
GPR40: EC5050 = 0.54 µM; COX1: IC50 = 13 µM; LO1: IC50 = 1 µM (soybean)
| 货品编码 | 规格 | 纯度 | 价格 (¥) | 现价(¥) | 特价(¥) | 库存描述 | 数量 | 总计 (¥) |
|---|---|---|---|---|---|---|---|---|
| SY0111-100g | 1kg | >97.0%(GC) | ¥ 0.00 | ¥ 0.00 | Instock | ¥ 0.00 | ||
| SY0111-100g | 500g | >97.0%(GC) | ¥ 1180.00 | ¥ 1180.00 | Instock | ¥ 0.00 | ||
| SY0111-100g | 100g | >97.0%(GC) | ¥ 336.00 | ¥ 336.00 | Instock | ¥ 0.00 | ||
| SY0111-25g | 25g | >97.0%(GC) | ¥ 119.00 | ¥ 119.00 | Instock | ¥ 0.00 | ||
| SY0111-5g | 5g | >97.0%(GC) | ¥ 36.00 | ¥ 36.00 | Instock | ¥ 0.00 |
| 中文别名 | 亚油酸;亞麻仁油酸;十八碳-9,12,15-三烯酸维生素F;十八碳二烯酸 (Z,Z)-9,12-十八烷二烯酸 十八碳-9,12-二烯酸 十八烷-9,12-二烯酸 顺,顺-9,12-十八碳二烯酸 |
| 英文别名 | Linoleic acid(CAS:60-33-3);Linoleic Acid; 60-33-3; Linolic Acid; Telfairic Acid; Cis,Cis-Linoleic Acid; (9Z,12Z)-Octadeca-9,12-Dienoic Acid; Linoleate; Cis,Cis-9,12-Octadecadienoic Acid; |
| CAS号 | 60-33-3 |
| Inchi | InChI=1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9- |
| InchiKey | OYHQOLUKZRVURQ-HZJYTTRNSA-N |
| 分子式 Molecular Weight | C18H32O2 |
| 分子量 Formula | 280.45 |
| 溶解度Solubility | Miscible with dimethyl sulfoxide, ethanol, ether, petroleum ether, dimethylformamide, acetone and benzene. Insoluble in water. |
| 性状 | liquid，液体 |
| 储藏条件 Storage conditions | -20℃避光保存 |
1.使用60-33-3实验前需戴好防护眼镜，穿戴防护服和口罩，佩戴手套，避免与皮肤接触。
2.使用60-33-3实验过程中如遇到有毒或者刺激性物质及有害物质产生，必要时实验操作需要手套箱内完成以免对实验人员造成伤害。
3.取样品60-33-3的移液枪头需及时更换，必要时为避免交叉污染尽可能选择滤芯吸头。
4.称量药品时选用称量纸，并无风处取药和称量以免扬撒，试剂的容器使用前务必确保干净，并消毒。
5.取药品60-33-3时尽量采用多个药勺分别使用，使用后清洗干净。
6.实验后产生的废弃物需分类存储，并交于专业生物废气物处理公司处理，以免造成环境污染。
大规格定制：定制产品请将信息发送至sales@bio-fount.com。
Experimental considerations:
1. Wear protective glasses, protective clothing and masks, gloves, and avoid contact with the skin during the experiment.
2. The waste generated after the experiment needs to be stored separately, and handed over to a professional biological waste gas treatment company to avoid environmental pollution.
| 产品说明 | 亚油酸(60-33-3)可通过增加细胞氧化剂状态和诱导线粒体功能障碍来诱导细胞凋亡,亚油酸价格,亚油酸参数见主页。 |
| Introduction | Linoleic Acid is a fatty acid that has been observed to influence the inflammatory process and regulate the functions of neutrophils. |
| Application1 | 亚油酸能与二甲基甲酰胺油脂溶剂和油类混溶，易溶于乙醚，溶于无水乙醇和石油醚，不溶于甘油和水，碘值181.1，硫氰值96.7，有刺激性， |
| Application2 | |
| Application3 |
| rganism | Test Type | Route | Dose | Effect | Reference |
|---|---|---|---|---|---|
| rat | LD50 | intraperitoneal | >50 gm/kg (50000 mg/kg) | Oyo Yakuri. Pharmacometrics., 4(327), 1970 | |
| mouse | LD50 | oral | >50 gm/kg (50000 mg/kg) | United States Patent Document., #3728459 | |
| mouse | LD50 | intraperitoneal | 280 mg/kg (280 mg/kg) | Yakugaku Zasshi. Journal of Pharmacy., 104(793), 1984 [PMID:6502467] |
Research has demonstrated that Linoleic Acid has cytotoxic activity and induces cell apoptosis by augmenting cellular oxidant status and inducing mitochondrial dysfunction. Additionally, the compound has been shown to stimulate the growth of MDA-MB-231 cells, increase the production of thromboxanes and prostaglandins, and reduce the levels of HHT and HETE. Linoleic Acid is an activator of PPAR.
| 警示图 | |
| 危险性 | warning |
| 危险性警示 | Not Available |
| 安全声明 | H303吞入可能有害+H313皮肤接触可能有害+H333吸入可能对身体有害 |
| 安全防护 | P264处理后彻底清洗+P280戴防护手套/穿防护服/戴防护眼罩/戴防护面具+P305如果进入眼睛+P351用水小心冲洗几分钟+P338取出隐形眼镜（如果有）并且易于操作,继续冲洗+P337如果眼睛刺激持续+P313获得医疗建议/护理 |
| 备注 | 避免吸入，误食以及与皮肤接触 |
| Pictogram(s) |  |
|---|---|
| Signal | Warning |
| GHS Hazard Statements |
Of the 8 notification(s) provided by 271 of 2348 companies with hazard statement code(s): H315 (91.51%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (76.01%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (67.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
| Precautionary Statement Codes |
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
| Srivastava, K.C., et al. 1982. Prostaglandins Leukot Med. 9: 669-684. PMID: 6818563 |
| Rose, D.P., et al. 1994. Cancer Res. 54: 6557-6562. PMID: 7987856 |
| Palmitate and oleate modify membrane fluidity and kinase activities of INS-1E β-cells alongside altered metabolism-secretion coupling PMID 31816355; Biochimica et biophysica acta. Molecular cell resea |
| Lu, X., et al. 2010. Lipids Health Dis. 9: 106. PMID: 20868498 |
| Rodrigues, H.G., et al. 2010. Lipids. 45: 809-819. PMID: 20730605 |
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