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L-半胱氨酸盐酸盐
NMR and HPLC COA下载 MSDS下载 - Names：
L-Cysteine hydrochloride，anhydrous
- CAS号：
52-89-1
MDL Number： MFCD00064553 - MF(分子式)： C3H7NO2S·HCI MW(分子量)： 157.62
- EINECS:200-157-7 Reaxys Number:
- Pubchem ID: Brand:BIOFOUNT
L-半胱氨酸盐酸盐(52-89-1,L-Cysteine hydrochloride) 是一种条件必需氨基酸，是硫化氢 (H2S)、谷胱甘肽和牛磺酸等生物活性分子的前体。L-Cysteine hydrochloride 能抑制胃饥饿素，降低啮齿动物和人类的食欲。
| 货品编码 | 规格 | 纯度 | 价格 (¥) | 现价(¥) | 特价(¥) | 库存描述 | 数量 | 总计 (¥) |
|---|---|---|---|---|---|---|---|---|
| SS3300-500g | 500g | 98% | ¥ 368.00 | ¥ 368.00 | 3-5days | ¥ 0.00 | ||
| SS3300-100g | 100g | 98% | ¥ 128.00 | ¥ 128.00 | 3-5days | ¥ 0.00 | ||
| SS3300-25g | 25g | 98% | ¥ 52.00 | ¥ 52.00 | 3-5days | ¥ 0.00 |
| 中文别名 | L-半胱氨酸盐酸盐(52-89-1);盐酸半胱氨酸;L-半胱氨酸盐酸盐(无水物);L-半胱氨酸盐酸盐无水物;L-半胱氨酸盐酸盐;L-2-氨基-3-巯基丙酸盐酸盐;半胱氨酸;盐酸半胱氨酸;半胱氨酸;半胱氨酸;半胱氨酸;半胱氨酸;半胱氨酸锌;（r）-半胱氨酸盐酸盐；（R）-半胱氨酸盐酸盐；3-巯基丙氨酸盐酸盐; 半胱氨酸氯化物；半胱氨酸水合物；半胱氨酸氯水合物; 半胱氨酸盐酸盐L-; 半胱氨酸水合物; |
| 英文别名 | L-Cysteine hydrochloride,anhydrous(52-89-1);L-Cysteine hydrochloride;anhydrous;Cysteine Cysteine Hydrochloride Half Cystine Half-CystineL Cysteine;L-Cysteine;Zinc Cysteinate; (r)-cysteinehydrochloride; (R)-Cysteine-hydrochloride; 3-Mercaptoalanine hydrochloride; Cystein chloride; Cysteine chlorhydrate;Cysteine chlorohydrate; Cysteine, hydrochloride, L-; cysteinechlorhydrate; |
| CAS号 | 52-89-1 |
| Inchi | InChI=1S/C3H7NO2S.ClH/c4-2(1-7)3(5)6;/h2,7H,1,4H2,(H,5,6);1H/t2-;/m0./s1 |
| InchiKey | IFQSXNOEEPCSLW-DKWTVANSSA-N |
| 分子式 Molecular Weight | C3H7NO2S·HCI |
| 分子量 Formula | 157.62 |
| 溶解度Solubility | Soluble in water. (580 g/L at 20°C)，H2O: 1M at?20?°C, clear, colorless。 |
| 性状 | White to light brown Solid |
| 储藏条件 Storage conditions | 充氩保存，Store at RT. |
L-半胱氨酸盐酸盐(52-89-1,L-Cysteine hydrochloride)毒理性质：
| 生物 | 测试类型 | 路线 | 剂量 | 影响 | 参考 |
| mouse | LD50 | intraperitoneal | 1250 mg/kg (1250 mg/kg) | National Technical Information Service., AD691-490 | |
| mouse | LD50 | intravenous | 771 mg/kg (771 mg/kg) | Japanese Journal of Antibiotics., 38(137), 1985 [PMID:3157807] | |
| mouse | LD50 | unreported | 3 gm/kg (3000 mg/kg) | British Journal of Cancer., 6(160), 1952 [PMID:14954086] |
L-半胱氨酸盐酸盐(52-89-1,L-Cysteine hydrochloride)实验注意事项：
1.使用52-89-1实验前需戴好防护眼镜，穿戴防护服和口罩，佩戴手套，避免与皮肤接触。
2.使用52-89-1实验过程中如遇到有毒或者刺激性物质及有害物质产生，必要时实验操作需要手套箱内完成以免对实验人员造成伤害。
3.取样品52-89-1的移液枪头需及时更换，必要时为避免交叉污染尽可能选择滤芯吸头。
4.称量药品时选用称量纸，并无风处取药和称量以免扬撒，试剂的容器使用前务必确保干净，并消毒。
5.取药品52-89-1时尽量采用多个药勺分别使用，使用后清洗干净。
6.实验后产生的废弃物需分类存储，并交于专业生物废气物处理公司处理，以免造成环境污染。
大规格定制：定制产品请将信息发送至sales@bio-fount.com。
L-半胱氨酸盐酸盐(52-89-1,L-Cysteine hydrochloride)Experimental considerations:
1. Wear protective glasses, protective clothing and masks, gloves, and avoid contact with the skin during the experiment.
2. The waste generated after the experiment needs to be stored separately, and handed over to a professional biological waste gas treatment company to avoid environmental pollution.
Tags：52-89-1试剂,52-89-1杂质,52-89-1密度,52-89-1溶解度,52-89-1旋光度,52-89-1闪点,52-89-1熔点,52-89-1购买,52-89-1结构式,52-89-1MSDS,
| 产品说明 | L-半胱氨酸盐酸盐(52-89-1)强酸味无臭仅有痕量亚硫酸盐气味,L-半胱氨酸盐酸盐溶解度,L-半胱氨酸盐酸盐msds详见主页. |
| Introduction | L-半胱氨酸盐酸盐(52-89-1,L-Cysteine hydrochloride)is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S) |
| Application1 | L-Cysteine hydrochloride is glutathione and taurine. L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents and humans |
| Application2 | L-半胱氨酸盐酸盐(52-89-1,L-Cysteine hydrochloride)是NMDA 谷氨酸能受体激动剂，在高浓度时，也是AMPA谷氨酸能受体激动剂 |
| Application3 | L-半胱氨酸氢氯化物被作为培养基补充剂，研究 Drosophila melanogaster代谢和睡眠表型。 |
L-半胱氨酸盐酸盐(52-89-1,L-Cysteine hydrochloride)药理学：
1、L-半胱氨酸盐酸盐是L-半胱氨酸的盐形式，可作为组氨酸氨裂解酶抑制剂。L-Cysteine hydrochloride是保健产品中的蛋白质补充剂。
2、L-Cysteine hydrochloride 是一种条件必需氨基酸，是硫化氢 (H2S)、谷胱甘肽和牛磺酸等生物活性分子的前体。L-Cysteine hydrochloride 能抑制胃饥饿素，降低啮齿动物和人类的食欲。
1、L-半胱氨酸盐酸盐是L-半胱氨酸的盐形式，可作为组氨酸氨裂解酶抑制剂。L-Cysteine hydrochloride是保健产品中的蛋白质补充剂。
2、L-Cysteine hydrochloride 是一种条件必需氨基酸，是硫化氢 (H2S)、谷胱甘肽和牛磺酸等生物活性分子的前体。L-Cysteine hydrochloride 能抑制胃饥饿素，降低啮齿动物和人类的食欲。
| 警示图 | |
| 危险性 | warning |
| 危险性警示 | LD50 intraperitoneal in mouse: 1250mg/kg |
| 安全声明 | H315,H319,H335 |
| 安全防护 | P261,P305+P351+P338 |
| 备注 | 避免吸入，误食以及与皮肤接触 |
L-半胱氨酸盐酸盐(52-89-1,L-Cysteine hydrochloride)危害标识：
| 象形图 |  |
| 信号 | Warning |
| GHS危险说明 | Aggregated GHS information provided by 1553 companies from 20 notifications to the ECHA C&L Inventory. |
| Reported as not meeting GHS hazard criteria by 28 of 1553 companies. For more detailed information, please visit ECHA C&L website | |
| Of the 19 notification(s) provided by 1525 of 1553 companies with hazard statement code(s): | |
| H319 (98.36%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] | |
| Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. | |
| 防范说明代码 | P264, P280, P305+P351+P338, and P337+P313 |
| (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| McGavigan AK, et al. L-cysteine suppresses ghrelin and reduces appetite in rodents and humans. Int J Obes (Lond). 2015 Mar;39(3):447-55. |
| Effect of reducing agents on oxidation-reduction potential and the outgrowth of Clostridium botulinum type E spores PMID 384903; Applied and environmental microbiology 1979 May; 37(5):978-84 Name matc |
| Effect of sodium chloride and pH on the outgrowth of spores of type E Clostridium botulinum at optimal and suboptimal temperatures PMID 5330680; Applied microbiology 1966 Jan; 14(1):49-54 Name matches |
| Transdermal patches loaded with L-cysteine HCL as a strategy for protection from mobile phone emitting electromagnetic radiation hazards PMID 30662314; Saudi pharmaceutical journal : SPJ : the officia |
| New solid medium for enhanced growth of Pasteurella tularensis PMID 13897160; Journal of bacteriology 1961 Oct; 82(?):564-9 Name matches: sodium thioglycolate cysteine-hcl |
L-半胱氨酸盐酸盐(52-89-1,L-Cysteine hydrochloride)参考文献：
1、High-potential use of L-Cysh modified bentonite for efficient removal of U(VI) from aqueous solution
Huai Chen, Quan Shui Chen, Bin Huang, Shi Wei Wang & Ling Yu Wang
Abstract In this work, a brand new organic superficial active sorbent L-Cysteine hydrochloride modified bentonite (LCMB) has been developed and proposed for treatment of contaminated water containing uranium. Correlation between different factors such as pH, contact time, temperature, initial concentration of U(VI) and efficiency of LCMB for uranium absorption are discussed. At uranium content in water from 25 to 250 mg L−1, the sorption capacity for LCMB reached 208.3 mg g−1 that is essentially higher in comparison with other sorbents and notably improved from 77 mg g−1 after modification.
2、In Vivo Bioluminescence Imaging of Intratumoral Bacteria
Michelle CroninAli R. AkinKevin P. FrancisMark Tangney
Abstract This chapter describes the use of whole-body bioluminescent imaging (BLI) for the study of bacterial trafficking in live mice, with an emphasis on the use of bacteria in therapy of cancer. Bacteria present an attractive class of vector for cancer therapy, possessing a natural ability to grow preferentially within tumors following systemic administration. Bacteria engineered to express the lux gene cassette permit BLI detection of the bacteria and tumor sites concurrently. The location and levels of bacteria within tumors over time can be readily examined, visualized in two or three dimensions. The method is applicable to a wide range of bacterial species and tumor xenograft types. This article describes the protocol for analysis of bioluminescent bacteria within subcutaneous tumor-bearing mice. This powerful, and inexpensive, real-time imaging strategy represents an ideal method for the study of bacteria in vivo in the context of cancer research. This protocol outlines the procedure for studying lux-tagged Escherichia coli and Bifidobacterium breve in mice, demonstrating the spatial and temporal readout from 2D and 3D BLI achievable with whole-body in vivo luminescence imaging.
3、Preconcentration of inorganic mercury and organic mercury with solvent extraction for neutron activation analysis
J. -G. Lo & J. -Y. Yang
Abstract A preconcentration method combined with neutron activation technique for the analysis of organic and inorganic mercury in waste water samples at ppb levels is presented. The inorganic mercury is extracted in CCl4 solution with lead diethyldithiocarbamate reagent and the organic mercury is extracted in C6H6 solution. Interfering activities of sodium and bromine are removed from the irradiated samples by this procedure. Two different solvent extraction procedures are also described in detail.
4、Synthesis and Antimicrobial Screening of Fused Heterocyclic Pyridines
Mahmoud A. A. El‐Remaily O. M. Elhady Eman M. M. Abdel‐Raheem
Abstract In an attempt to find a new class of antimicrobial agents, a series of pyridoxazepine, pyridothiazepine, triazepine, naphthyridine, pyridopyrimidine, and other related products containing pyridine moiety were synthesized via the reaction of 2‐amino‐6‐chloro‐3,5‐dicyanopyridine 1 with nucleophilic chemical reagents. These compounds were screened for cytotoxicity and their antimicrobial activity. Most of products showed inhibitory effect.
1、High-potential use of L-Cysh modified bentonite for efficient removal of U(VI) from aqueous solution
Huai Chen, Quan Shui Chen, Bin Huang, Shi Wei Wang & Ling Yu Wang
Abstract In this work, a brand new organic superficial active sorbent L-Cysteine hydrochloride modified bentonite (LCMB) has been developed and proposed for treatment of contaminated water containing uranium. Correlation between different factors such as pH, contact time, temperature, initial concentration of U(VI) and efficiency of LCMB for uranium absorption are discussed. At uranium content in water from 25 to 250 mg L−1, the sorption capacity for LCMB reached 208.3 mg g−1 that is essentially higher in comparison with other sorbents and notably improved from 77 mg g−1 after modification.
2、In Vivo Bioluminescence Imaging of Intratumoral Bacteria
Michelle CroninAli R. AkinKevin P. FrancisMark Tangney
Abstract This chapter describes the use of whole-body bioluminescent imaging (BLI) for the study of bacterial trafficking in live mice, with an emphasis on the use of bacteria in therapy of cancer. Bacteria present an attractive class of vector for cancer therapy, possessing a natural ability to grow preferentially within tumors following systemic administration. Bacteria engineered to express the lux gene cassette permit BLI detection of the bacteria and tumor sites concurrently. The location and levels of bacteria within tumors over time can be readily examined, visualized in two or three dimensions. The method is applicable to a wide range of bacterial species and tumor xenograft types. This article describes the protocol for analysis of bioluminescent bacteria within subcutaneous tumor-bearing mice. This powerful, and inexpensive, real-time imaging strategy represents an ideal method for the study of bacteria in vivo in the context of cancer research. This protocol outlines the procedure for studying lux-tagged Escherichia coli and Bifidobacterium breve in mice, demonstrating the spatial and temporal readout from 2D and 3D BLI achievable with whole-body in vivo luminescence imaging.
3、Preconcentration of inorganic mercury and organic mercury with solvent extraction for neutron activation analysis
J. -G. Lo & J. -Y. Yang
Abstract A preconcentration method combined with neutron activation technique for the analysis of organic and inorganic mercury in waste water samples at ppb levels is presented. The inorganic mercury is extracted in CCl4 solution with lead diethyldithiocarbamate reagent and the organic mercury is extracted in C6H6 solution. Interfering activities of sodium and bromine are removed from the irradiated samples by this procedure. Two different solvent extraction procedures are also described in detail.
4、Synthesis and Antimicrobial Screening of Fused Heterocyclic Pyridines
Mahmoud A. A. El‐Remaily O. M. Elhady Eman M. M. Abdel‐Raheem
Abstract In an attempt to find a new class of antimicrobial agents, a series of pyridoxazepine, pyridothiazepine, triazepine, naphthyridine, pyridopyrimidine, and other related products containing pyridine moiety were synthesized via the reaction of 2‐amino‐6‐chloro‐3,5‐dicyanopyridine 1 with nucleophilic chemical reagents. These compounds were screened for cytotoxicity and their antimicrobial activity. Most of products showed inhibitory effect.
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