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弹性蛋白酶
NMR and HPLC COA下载 MSDS下载 - Names：
Elastase
- CAS号：
39445-21-1
MDL Number： MFCD00130998 - MF(分子式)： MW(分子量)：
- EINECS:254-453-6 Reaxys Number:
- Pubchem ID: Brand:BIOFOUNT
弹性蛋白酶(39445-21-1,Elastase)是一种由多个氨基酸组成的单一肽链，能促进结缔组织中蛋白质的消化和分解，包括针对肽键进行的相应结合，加水分解等，弹性蛋白酶还具有明显的蛋白酶作用，能针对磷脂酶进行活化，降低身体血液中的胆固醇，还能改善身体内的血脂血清，进而降低血液中密度脂蛋白，从而能增加身体的血液循环，增加血管弹性。
| 货品编码 | 规格 | 纯度 | 价格 (¥) | 现价(¥) | 特价(¥) | 库存描述 | 数量 | 总计 (¥) |
|---|---|---|---|---|---|---|---|---|
| SS2210-1g | 1g | 生物技术级 | ¥ 678.00 | ¥ 678.00 | 3-5days | ¥ 0.00 |
| 中文别名 | 弹性蛋白酶,弹性蛋白酶(39445-21-1,Elastase);弹性水解酶;弹性硬朊酶;胰肽酶I;弹性蛋白酶,来源猪胰腺;胰酞酶E;弹性蛋白酶(猪胰) |
| 英文别名 | Elastase(39445-21-1);Elastase from porcine pancreas(Lyophilized) |
| CAS号 | 39445-21-1 |
| Inchi | No data available |
| InchiKey | No data available |
| 分子式 Molecular Weight | |
| 分子量 Formula | |
| 溶解度Solubility | Soluble in water |
| 性状 | 白色粉末 |
| 储藏条件 Storage conditions | Store at 4°C,-4℃下存储更优 |
弹性蛋白酶(39445-21-1,Elastase)实验注意事项：
1.实验前需戴好防护眼镜，穿戴防护服和口罩，佩戴手套，避免与皮肤接触。
2.实验过程中如遇到有毒或者刺激性物质及有害物质产生，必要时实验操作需要手套箱内完成以免对实验人员造成伤害。
3.取样品的移液枪头需及时更换，必要时为避免交叉污染尽可能选择滤芯吸头。
4.称量药品时选用称量纸，并无风处取药和称量以免扬撒，试剂的容器使用前务必确保干净，并消毒。
5.取药品时尽量采用多个药勺分别使用，使用后清洗干净后，烘干消毒存放。
6.实验后产生的废弃物需分类存储，并交于专业生物废气物处理公司处理，以免造成环境污染。
Elastase(39445-21-1) Experimental considerations:
1. Wear protective glasses, protective clothing and masks, gloves, and avoid contact with the skin during the experiment.
2. The waste generated after the experiment needs to be stored separately, and handed over to a professional biological waste gas treatment company to avoid environmental pollution.
Tag:弹性蛋白酶(39445-21-1,Elastase),弹性蛋白酶的活性,弹性蛋白酶的作用,弹性蛋白酶的外观,弹性蛋白酶的使用注意事项,弹性蛋白酶的价格,弹性蛋白酶的成分,弹性蛋白酶的生产,弹性蛋白酶的使用条件,弹性蛋白酶的储存
| 产品说明 | 弹性蛋白酶(39445-21-1,Elastase)仅用于科学研究实验使用,弹性蛋白酶MSDS,弹性蛋白酶溶解度见主页。 |
| Introduction | Elastase (39445-21-1,弹性蛋白酶) is used in chemical synthesis intermediates and scientific research use, 39445-21-1 structural formula, MSDS and application see homepage |
| Application1 | |
| Application2 | |
| Application3 |
| 警示图 | |
| 危险性 | warning |
| 危险性警示 | No data available |
| 安全声明 | H315,H319,H335 |
| 安全防护 | P264处理后彻底清洗+P280戴防护手套/穿防护服/戴防护眼罩/戴防护面具+P305如果进入眼睛+P351用水小心冲洗几分钟+P338取出隐形眼镜（如果有）并且易于操作,继续冲洗+P337如果眼睛刺激持续+P313获得医疗建议/护理 |
| 备注 | 避免吸入，误食以及与皮肤接触 |
| Effects of low and standard intra-abdominal pressure on systemic inflammation and immune response in laparoscopic adrenalectomy: A prospective randomised study. |
| Molecular characterization of serine protease inhibitor isoform 3, SmSPI, from Schistosoma mansoni. |
| Proteomic Characterization of Middle Ear Fluid Confirms Neutrophil Extracellular Traps as a Predominant Innate Immune Response in Chronic Otitis Media. |
| The levels of serine proteases in colon tissue interstitial fluid and serum serve as an indicator of colorectal cancer progression. |
1.Effects of low and standard intra-abdominal pressure on systemic inflammation and immune response in laparoscopic adrenalectomy: A prospective randomised study.
Schietroma M1, Pessia B1, Stifini D1, Lancione L1, Carlei F1, Cecilia EM1, Amicucci G1. J Minim Access Surg. 2016 Apr-Jun;12(2):109-17. doi: 10.4103/0972-9941.178513.
BACKGROUND: The advantages of laparoscopic adrenalectomy (LA) over open adrenalectomy are undeniable. Nevertheless, carbon dioxide (CO2) pneumoperitoneum may have an unfavourable effect on the local immune response. The aim of this study was to compare changes in the systemic inflammation and immune response in the early post-operative (p.o.) period after LA performed with standard and low-pressure CO2 pneumoperitoneum.
2.Molecular characterization of serine protease inhibitor isoform 3, SmSPI, from Schistosoma mansoni.
Pakchotanon P1, Molee P1,2, Nuamtanong S1, Limpanont Y3, Chusongsang P3, Limsomboon J3, Chusongsang Y3, Maneewatchararangsri S4, Chaisri U2, Adisakwattana P5,6. Parasitol Res. 2016 Apr 16. [Epub ahead of print]
Serine protease inhibitors, known as serpins, are pleiotropic regulators of endogenous and exogenous proteases, and molecule transporters. They have been documented in animals, plants, fungi, bacteria, and viruses; here, we characterize a serpin from the trematode platyhelminth Schistosoma mansoni. At least eight serpins have been found in the genome of S. mansoni, but only two have characterized molecular properties and functions. Here, the function of S. mansoni serpin isoform 3 (SmSPI) was analyzed, using both computational and molecular biological approaches. Phylogenetic analysis showed that SmSPI was closely related to Schistosoma haematobium serpin and Schistosoma japonicum serpin B10. Structure determined in silico confirmed that SmSPI belonged to the serpin superfamily, containing nine α-helices, three β-sheets, and a reactive central loop. SmSPI was highly expressed in schistosomules, predominantly in the head gland, and in adult male and female with intensive accumulation on the spines, which suggests that it may have a role in facilitating intradermal and intravenous survival.
3.Proteomic Characterization of Middle Ear Fluid Confirms Neutrophil Extracellular Traps as a Predominant Innate Immune Response in Chronic Otitis Media.
Val S1, Poley M1, Brown K2, Choi R1, Jeong S1, Colberg-Poley A2, Rose MC2, Panchapakesan KC2, Devaney JC2, Perez-Losada M2, Preciado D1,3. PLoS One. 2016 Apr 14;11(4):e0152865. doi: 10.1371/journal.pone.0152865. eCollection 2016.
BACKGROUND: Chronic Otitis Media (COM) is characterized by middle ear effusion (MEE) and conductive hearing loss. MEE reflect mucus hypersecretion, but global proteomic profiling of the mucosal components are limited.
4.The levels of serine proteases in colon tissue interstitial fluid and serum serve as an indicator of colorectal cancer progression.
Xie Y1,2, Chen L3, Lv X4, Hou G1,2, Wang Y1,2, Jiang C4, Zhu H3, Xu N3, Wu L1,2, Lou X1,2, Liu S1,2,4,5. Oncotarget. 2016 Apr 11. doi: 10.18632/oncotarget.8693. [Epub ahead of print]
The proteins in tissue interstitial fluids (TIFs) can spread into the blood and have been proposed as an ideal material to find blood biomarkers. The colon TIFs were collected from 8-, 13-, 18-, and 22-week ApcMin/+, a typical mouse model of colorectal cancer (CRC), and wild-type mice. iTRAQ-based quantification proteomics was conducted to survey the TIF proteins whose abundance appeared to depend on tumor progression. A total of 46 proteins that exhibited consecutive changes in abundance were identified, including six serine proteases, chymotrypsin-like elastase 1 (CELA1), chymotrypsin-like elastase 2A (CEL2A), chymopasin, chymotrypsinogen B (CTRB1), trypsin 2 (TRY2), and trypsin 4 (TRY4). The observed increases in the abundance of serine proteases were supported in another quantitative evaluation of the individual colon TIFs using a multiple reaction monitor (MRM) assay. Importantly, the increases in the abundance of serine proteases were also verified in the corresponding sera.
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