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-
DTT
NMR and HPLC COA下载 MSDS下载 - Names：
DTT(二硫苏糖醇)
- CAS号：
3483-12-3
MDL Number： MFCD00004877 - MF(分子式)： C4H10O2S2 MW(分子量)： 154.25
- EINECS:222-468-7 Reaxys Number:
- Pubchem ID: Brand:BIOFOUNT
| 货品编码 | 规格 | 纯度 | 价格 (¥) | 现价(¥) | 特价(¥) | 库存描述 | 数量 | 总计 (¥) |
|---|---|---|---|---|---|---|---|---|
| SS1741-25g | 25g | 99% | ¥ 680.00 | ¥ 680.00 | Instock | ¥ 0.00 | ||
| SS1741-5g | 5g | 99% | ¥ 166.00 | ¥ 166.00 | Instock | ¥ 0.00 | ||
| SS1741-1g | 1g | 99% | ¥ 68.00 | ¥ 68.00 | Instock | ¥ 0.00 | ||
| HCM000375-2kg | 2kg | 98% | ¥ 17000.00 | ¥ 17000.00 | Backorder | ¥ 0.00 | ||
| HCM000375-500g | 500g | 98% | ¥ 4500.00 | ¥ 4500.00 | Backorder | ¥ 0.00 | ||
| HCM000375-25g | 25g | 98% | ¥ 650.00 | ¥ 650.00 | Instock | ¥ 0.00 | ||
| HCM000375-5g | 5g | 98% | ¥ 166.00 | ¥ 166.00 | Instock | ¥ 0.00 | ||
| HCM000375-1g | 1g | 98% | ¥ 48.00 | ¥ 48.00 | Instock | ¥ 0.00 |
| 中文别名 | 二硫苏糖醇,二硫苏糖醇(3483-12-3,DL-Dithiothreitol);1,4-二硫代-DL-苏糖醇;DL-二硫苏糖醇;DL-1,4-二硫苏糖醇; DTT |
| 英文别名 | DL-Dithiothreitol(3483-12-3);DTT;DL-1,4-Dithiothreitol;Dithiothreitol;dl-Dithiothreitol |
| CAS号 | 3483-12-3 |
| Inchi | InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m1/s1 |
| InchiKey | VHJLVAABSRFDPM-QWWZWVQMSA-N |
| 分子式 Molecular Weight | C4H10O2S2 |
| 分子量 Formula | 154.25 |
| 溶解度Solubility | H2O: soluble 50 mg/mL, clear, colorless to very faintly yellow； water 15.42,最高浓度 mM100 |
| 性状 | 白色固体粉末 |
| 储藏条件 Storage conditions | 极易氧化，2-8℃密闭保存 |
| 生物 | 测试类型 | 路线 | 报告剂量（标准化剂量） | 影响 | 参考 |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 179 mg/kg (179 mg/kg) | Journal of Medicinal Chemistry., 15(600), 1972 |
Cleland试剂，也称为二硫苏糖醇或DTT，是巯基的水溶性保护剂。 它减少了二硫键与蛋白质和酶中游离巯基的连接。二硫苏糖醇是用于蛋白质分离和纯化方案的缓冲液的组成部分。
二硫苏糖醇(3483-12-3,DL-Dithiothreitol)配制储备液：
| 浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 6.48 mL | 32.41 mL | 64.83 mL |
| 5 mM | 1.3 mL | 6.48 mL | 12.97 mL |
| 10 mM | 0.65 mL | 3.24 mL | 6.48 mL |
| 50 mM | 0.13 mL | 0.65 mL | 1.3 mL |
二硫苏糖醇(3483-12-3,DL-Dithiothreitol)实验注意事项：
1.实验前需戴好防护眼镜，穿戴防护服和口罩，佩戴手套，避免与皮肤接触。
2.实验过程中如遇到有毒或者刺激性物质及有害物质产生，必要时实验操作需要手套箱内完成以免对实验人员造成伤害。
3.取样品的移液枪头需及时更换，必要时为避免交叉污染尽可能选择滤芯吸头。
4.称量药品时选用称量纸，并无风处取药和称量以免扬撒，试剂的容器使用前务必确保干净，并消毒。
5.取药品时尽量采用多个药勺分别使用，使用后清洗干净后，烘干消毒存放。
6.实验后产生的废弃物需分类存储，并交于专业生物废气物处理公司处理，以免造成环境污染。
DL-Dithiothreitol(3483-12-3) Experimental considerations:
1. Wear protective glasses, protective clothing and masks, gloves, and avoid contact with the skin during the experiment.
2. The waste generated after the experiment needs to be stored separately, and handed over to a professional biological waste gas treatment company to avoid environmental pollution.
Tags:二硫苏糖醇溶解度,二硫苏糖醇密度,二硫苏糖醇pbs缓冲液内溶解度,二硫苏糖醇物理性状,二硫苏糖醇外观,二硫苏糖醇规格,二硫苏糖醇厂家,二硫苏糖醇手性异构体,二硫苏糖醇手性分子,二硫苏糖醇水溶解性,二硫苏糖醇有机溶剂溶解性,二硫苏糖醇DMSO溶解性,二硫苏糖醇储备液,
| 产品说明 | 二硫苏糖醇(3483-12-3,DL-Dithiothreitol)仅做科学研究使用,二硫苏糖醇的毒性,二硫苏糖醇的作用,二硫苏糖醇的配制等其他参数见主页 |
| Introduction | DL-Dithiothreitol (3483-12-3,二硫苏糖醇) is only used for scientific research, the function of 3483-12-3, the preparation of 3483-12-3 and other parameters can be found on the homepage |
| Application1 | DTT和巯基乙醇相比，作用相似，但DTT的刺激性气味要小很多，毒性也比巯基乙醇低很多 |
| Application2 | 二硫苏糖醇常用还原剂，有抗氧化作用 |
| Application3 | DTT is a component of buffers used in protocols for the isolation and purification of proteins. |
| 警示图 | |
| 危险性 | warning |
| 危险性警示 | No data available |
| 安全声明 | H302,H315,H319,H335 |
| 安全防护 | P261-P264b-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P330-P362-P403+P233-P501c |
| 备注 | 实验过程中防止吸入、食入，做好安全防护 |
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth. Take off contaminated clothing and wash before reuse. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/ container to an approved waste disposal plant
| 象形图 |  |
|---|---|
| 信号 | Warning |
| GHS危险说明 |
Aggregated GHS information provided by 239 companies from 16 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (96.23%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
| 防范说明代码 |
P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Sears et al (1977) Relative susceptibilities of the interchain disulfides of an immunoglobulin G molecule to reduction by dithiothreitol. Biochemistry 16 2031 PMID: 403938 |
| Jabusch et al (1978) The effect of thiodiglycol and dithiothreitol on the alkaline hydrolysis products of certain amino acid phenylthiohydantoins. Anal.Biochem. 91 532 PMID: 9762140 |
| Suppression of GABAB receptor function in vivo by disulfide reducing agent, dl-dithiothreitol (DTT)(Psychopharmacology,2004) |
| Improving the Bacterial Recovery by Using Dithiothreitol with Aerobic and Anaerobic Broth in Biofilm-Related Prosthetic and Joint Infections |
| Cellular Oxygen Utilization and Hypoxia: Interaction of Dithiols with Cellular Electron Transfer Systems(Oxygen Transport to Tissue VIII,1986) |
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