RS 42358-197|(S)-2-(quinuclidin-3-yl)-2,4,5,6-tetrahydro-1H-benzo[de]isoquinolin-1-one hydrochloride|135729-55-4|-范德生物科技公司

RS 42358-197

RS 42358-197
NMR and HPLC COA下载 MSDS下载
Names：
(S)-2-(quinuclidin-3-yl)-2,4,5,6-tetrahydro-1H-benzo[de]isoquinolin-1-one hydrochloride
CAS号：
135729-55-4
MDL Number：
MF(分子式)： C19H23ClN2O MW(分子量)： 330.85
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

货品编码	规格	纯度	价格 (¥)	现价(¥)	特价(¥)	库存描述	数量	总计 (¥)
FMK18879-15mg	15mg	>98%	¥ 19180.00	¥ 19180.00		2 Weeks	- +	¥ 0.00

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中文别名	(S)-2-(quinuclidin-3-yl)-2,4,5,6-tetrahydro-1H-benzo[de]isoquinolin-1-one hydrochloride
英文别名	RS 42358-197; RS42358-197; RS-42358-197;
CAS号	135729-55-4
SMILES	O=C1N([C@@H]2CN3CCC2CC3)C=C4C5=C1C=CC=C5CCC4.[H]Cl
Inchi	InChI=1S/C19H22N2O.ClH/c22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-21(19)17-12-20-9-7-13(17)8-10-20;/h2,4,6,11,13,17H,1,3,5,7-10,12H2;1H/t17-;/m1./s1
InchiKey	PEMWWRCTBNOHCX-UNTBIKODSA-N
分子式 Molecular Weight	C19H23ClN2O
分子量 Formula	330.85
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility	Soluble in DMSO
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	RS 42358-197(CAS:135729-55-4):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	RS 42358-197 is the S-isomer of the novel 5-HT3 receptor antagonist RS-42358.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Costall B, Domeney AM, Kelly ME, Tomkins DM, Naylor RJ, Wong EH, Smith WL, Whiting RL, Eglen RM. The effect of the 5-HT3 receptor antagonist, RS-42358-197, in animal models of anxiety. Eur J Pharmacol. 1993 Mar 30;234(1):91-9. PubMed PMID: 8097165.

[2]Eglen RM, Lee CH, Smith WL, Johnson LG, Whiting RL, Hegde SS. RS 42358-197, a novel and potent 5-HT3 receptor antagonist, in vitro and in vivo. J Pharmacol Exp Ther. 1993 Aug;266(2):535-43. PubMed PMID: 8355189.

[3] Wong EH, Bonhaus DW, Wu I, Stefanich E, Eglen RM. Labelling of 5-hydroxytryptamine3 receptors with a novel 5-HT3 receptor ligand, [3H]RS-42358-197. J Neurochem. 1993 Mar;60(3):921-30. PubMed PMID: 8436978.

[4] Bonhaus DW, Wong EH, Stefanich E, Kunysz EA, Eglen RM. Pharmacological characterization of 5-hydroxytryptamine3 receptors in murine brain and ileum using the novel radioligand [3H]RS-42358-197: evidence for receptor heterogeneity. J Neurochem. 1993 Nov;61(5):1927-32. PubMed PMID: 8229003.

[5] Wong EH, Bonhaus DW, Eglen RM. The identification of heterogeneity of 5-HT3 receptors with [3H]RS-42358-197. Adv Exp Med Biol. 1995;36

3:97-108. PubMed PMID: 7618534.

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